Results 181 to 190 of about 4,989,359 (237)

Synthesis of O-glycolyl-linked neuraminic acids through a spirocyclic intermediate.

Organic Letters, 2002
[reaction: see text] The neuraminic acid derivative 5 is readily converted in several steps to the neuraminic acid dimer 12, linked through the hydroxyl of a 5-N-glycolyl group in an alpha-2,5 glycosidic linkage.
J. Mcauliffe, David Rabuka, O. Hindsgaul
semanticscholar   +1 more source

Determination of neuraminic acid in cerebral tissues

Analytical Biochemistry, 1960
Abstract The concentration of neuraminic acid was determined in the gray matter of the insular and temporal cortex as well as of the basal ganglia, and in the white matter of normal autopsy human brains. Samples from the cerebral tissues were separated into two fractions: a water-soluble lipid and a lipid-free residue.
openaire   +3 more sources

Circular dichroism of oligosaccharides containing neuraminic acid

Biochemistry, 1975
In order to test the usefulness of circular dichroism in stereochemical and structural studies of oligosaccharides of glycoproteins, we measured the circular dichroism (CD) for N-acetylneuraminic acid (NAcNA) and several derivates. By acidic mathanolysis, we have prepared the deacetylated methyl ester, methyl glycoside of NAcNA, as well as a saponified
Bush Ca, Dickinson Hr
openaire   +3 more sources

Characterization of visna virus envelope neuraminic acid

Journal of Virology, 1977
Visna virus particles inhibit influenza virus hemagglutination in an assay for neuraminic acid-containing viruses. Pretreatment of visna virus with neuraminidase abolished hemagglutination inhibition activity but did not significantly affect attachment, infectivity, or virus-induced cell fusion in sheep choroid plexus cell monolayers.
Richard W. Compans, Donald H. Harter, M J August   +2 more
openaire   +3 more sources

Dialysable Neuraminic Acid in Human Cerebrospinal Fluid

Nature, 1962
BECAUSE of the presence of interfering sugars in great excess, it has not been possible heretofore to determine with any certainty in other laboratories as well as our own1 whether neuraminic acid occurs in dialysable form in cerebrospinal fluid. Recent methods developed in this laboratory for the quantitative fractionation of all the carbohydrate ...
Peter Evans, Samuel Bogoch
openaire   +2 more sources

Inhibition of neuraminidase with neuraminic acid C -glycosides

Bioorganic & Medicinal Chemistry Letters, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Qun Wang, Michael W. Wolff, Yuguo Du, Robert J. Linhardt, Tülay Polat   +4 more
openaire   +4 more sources

Analogues of Sialic Acids as Potential Sialidase Inhibitors Synthesis of 2‐C‐Hydroxymethyl Derivatives of N‐Acetyl‐6‐amino‐2,6‐dideoxy‐neuraminic Acid

, 1990
The intramolecular cycloaddition of the previously described azidoalkene 16, the related diacetates 7 and 13, and the monoacetate 8 led diastereoselectivity to the (2R)- and (2S)-configurated hydropyridotriazoles 17, 9 and 11, 14 and 15, and 10 and 12 ...
B. Bernet, A. B. Murty, A. Vasella
semanticscholar   +1 more source

Cerebrospinal Fluid Neuraminic Acid Deficiency in Schizophrenia

Archives of Neurology And Psychiatry, 1958
With the thought that metabolic disturbances nuclear to the schizophrenic process might best be studied in the central nervous system itself, the attention of this laboratory has been directed to certain little-known chemical constituents of the brain and cerebrospinal fluid.
openaire   +3 more sources

Zur Histochemie der Neuramins�ure [PDF]

Histochemie, 1969
Bei der Methylierung mit methanolischer Salzsaure wird ein Grosteil der Neuraminsaure aus dem Gewebe freigesetzt. Da in gleicher Weise bei der Methylierung die schwefelsauren Gruppen der sauren Mucopolysaccharide abgespalten werden, ist ein histotopochemischer Nachweis der Neuraminsaure aus der Herabsetzung der Alcianblaufarbbarkeit nach Methylierung ...
openaire   +3 more sources

Analysis of O-Acetylated Sialic Acids in Dried Blood Spots.

Analytical Chemistry, 2019
Sialic acid is a family of N- and O-substitutions of neuraminic acid. Plasma or serum sialic acid has been established as a potential disease marker. For example, the presence of 9- O-acetyl on the sialic acid of some glycans and glycoconjugates (e.g., 9-
Qiwei Zhang, Yawei Wang, Qi Zheng, Jianjun Li   +3 more
semanticscholar   +1 more source