Results 41 to 50 of about 134,617 (294)

Semi-automatic quantification of neurite fasciculation in high-density neurite images by the neurite directional distribution analysis (NDDA) [PDF]

Journal of Neuroscience Methods, 2014
Bundling of neurite extensions occur during nerve development and regeneration. Understanding the factors that drive neurite bundling is important for designing biomaterials for nerve regeneration toward the innervation target and preventing nociceptive collateral sprouting.
Amy M, Hopkins, Brandon, Wheeler, Cristian, Staii, David L, Kaplan, Timothy J, Atherton   +4 more
openaire   +2 more sources

Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism. [PDF]

PLoS ONE, 2015
Neurodegenerative diseases are linked to neuronal cell death and impairment of neurite outgrowth. An edible mushroom, Pleurotus giganteus was found to stimulate neurite outgrowth in vitro but the chemical constituents and the underlying mechanism is yet ...
Chia-Wei Phan, Pamela David, Kah-Hui Wong, Murali Naidu, Vikineswary Sabaratnam   +4 more
doaj   +1 more source

CircRtn4 Acts as the Sponge of miR-24-3p to Promote Neurite Growth by Regulating CHD5

Frontiers in Molecular Neuroscience, 2021
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules. After derived from precursor mRNA back-splicing, circRNAs play important roles in many biological processes.
Yue Qi, Nana Ma, Xiaofan Chen, Yue Wang, Wei Zhang, Wei Zhang, Jun Wan, Jun Wan, Jun Wan   +8 more
doaj   +1 more source

Binding between the neural cell adhesion molecules axonin-1 and Nr- CAM/Bravo is involved in neuron-glia interaction [PDF]

, 1995
Neural cell adhesion molecules of the immunoglobulin superfamily mediate cellular interactions via homophilic binding to identical molecules and heterophilic binding to other family members or structurally unrelated cell-surface glycoproteins.
Buchstaller, Andrea, Dreyer, William J., Giger, Roman J., Pollerberg, G. Elisabeth, Sonderegger, Peter, Suter, Daniel M.   +5 more
core   +4 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The lncRNA MALAT1/miR-30/Spastin Axis Regulates Hippocampal Neurite Outgrowth

Frontiers in Cellular Neuroscience, 2020
Spastin, a microtubule-severing enzyme, is important for neurite outgrowth. However, the mechanisms underlying the post-transcriptional regulation of spastin during microtubule-related processes are largely unknown.
Tao Jiang, Tao Jiang, Zhenbin Cai, Zhisheng Ji, Jianyu Zou, Zhi Liang, Guowei Zhang, Yaozhong Liang, Hongsheng Lin, Minghui Tan   +9 more
doaj   +1 more source

Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]

, 2011
Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L, Conovaloff, Aaron W, Irazoqui, Pedro P, Panitch, Alyssa   +3 more
core   +1 more source

Molecular mechanisms of neurite extension [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1999
The extension of neurites is a major task of developing neurons, requiring a significant metabolic effort to sustain the increase in molecular synthesis necessary for plasma membrane expansion. In addition, neurite extension involves changes in the subsets of expressed proteins and reorganization of the cytomatrix.
VALTORTA, FLAVIA, Leoni, C.
openaire   +3 more sources

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Multi-scale engineering for neuronal cell growth and differentiation [PDF]

, 2011
In this paper we investigate the role of micropatterning and molecular coating for cell culture and differentiation of neuronal cells (Neuro2a cell line) on a polydimethylsiloxane substrate.
Béduer, Amélie, Flahaut, Emmanuel, Loubinoux, Isabelle, Seichepine, Florent, Vaysse, Laurence, Vieu, Christophe   +5 more
core   +4 more sources