Results 11 to 20 of about 87,065 (293)
Bio-Protocol, 2016 Neurite outgrowth in culture provides an easy way to determine the effects of a particular substrate or exogenous factor on neuron behavior. Dissociated neurons can be plated on a variety of substrates and the length of the longest neurite outgrowth can ...
Angela Filous, Jerry Silver
doaj +3 more sources
Two distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowth. [PDF]
PLoS ONE, 2010 BACKGROUND: The process of neurite outgrowth is the initial step in producing the neuronal processes that wire the brain. Current models about neurite outgrowth have been derived from classic two-dimensional (2D) cell culture systems, which do not ...
Kyung-Jin Jang +5 more
doaj +4 more sources
Proteoglycans: Road Signs for Neurite Outgrowth [PDF]
Neural Regeneration Research, 2014 Proteoglycans in the central nervous system play integral roles as "traffic signals" for the direction of neurite outgrowth. This attribute of proteoglycans is a major factor in regeneration of the injured central nervous system. In this review, the structures of proteoglycans and the evidence suggesting their involvement in the response following ...
Beller, Justin A., Snow, Diane M.
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Characterization of BASP1‐mediated neurite outgrowth
Journal of Neuroscience Research, 2008 AbstractThe brain acid‐soluble protein BASP1 (CAP‐23, NAP‐22) belongs to the family of growth‐associated proteins, which also includes GAP‐43, a protein recently shown to regulate neural cell adhesion molecule (NCAM)‐mediated neurite outgrowth. Here, the effects of BASP1 overexpression were investigated in PC12E2 cells and primary hippocampal neurons ...
Korshunova, Irina +5 more
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Matrix interactions modulate neurotrophin-mediated neurite outgrowth and pathfinding
Neural Regeneration Research, 2015 Both matrix biochemistry and neurotrophic factors are known to modulate neurite outgrowth and pathfinding however, the interplay between these two factors is less studied.
Christopher M Madl, Sarah C Heilshorn
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An organized 3D in vitro model for peripheral nerve studies [PDF]
, 2013 Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
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Neurite Outgrowth: A Flick of the Wrist [PDF]
Current Biology, 2007 A new study has shown that, near the tip of a growing axon, dephosphorylation of the microtubule-associated protein Doublecortin is controlled by protein phosphatase 1 and its regulator spinophilin. This results in spatially regulated microtubule bundling within the axon and more efficient axon outgrowth.
Dehmelt, L., Halpain, S.
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TSH enhances neurite outgrowth. [PDF]
Front Endocrinol (Lausanne)Extra-thyroidal effects of TSH have been reported in various tissues expressing the TSH receptor (TSHR) including several areas of the brain. However, the influence of TSH on neuronal phenotypes has not been examined. Using a well-characterized human neuroblastoma cell line (SH-SY5Y), we have examined TSH signaling effects on the phenotype of these ...
Mansoori M +4 more
europepmc +4 more sources
Glycomimetic Cyclic Peptides Stimulate Neurite Outgrowth
Angewandte Chemie International Edition, 2006 Baechle D, Loers G, Guthöhrlein EW, Schachner M, Sewald N. Glycomimetic cyclic peptides stimulate neurite outgrowth. Angewandte Chemie International Edition.
Baechle, Dirk +4 more
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Effects of MAP4K inhibition on neurite outgrowth. [PDF]
Mol Brain, 2023 AbstractProtein kinases are responsible for protein phosphorylation and are involved in important intracellular signal transduction pathways in various cells, including neurons; however, a considerable number of poorly characterized kinases may be involved in neuronal development.
Lasham DJ +7 more
europepmc +4 more sources