Results 41 to 50 of about 87,065 (293)
An Integrated Cytoskeletal Model of Neurite Outgrowth [PDF]
Frontiers in Cellular Neuroscience, 2018 Neurite outgrowth underlies the wiring of the nervous system during development and regeneration. Despite a significant body of research, the underlying cytoskeletal mechanics of growth and guidance are not fully understood, and the relative contributions of individual cytoskeletal processes to neurite growth are controversial.
Kyle E. Miller +4 more
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Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants
Brain Sciences, 2020 Background: The spatial gap between cochlear implants (CIs) and the auditory nerve limits frequency selectivity as large populations of spiral ganglion neurons (SGNs) are electrically stimulated synchronously.
Claudia Frick +12 more
doaj +1 more source
Outgrowth of neurites is a dual process
Communicative & Integrative Biology, 2010 In neurons and neurosecretory (nerve) cells, neurite outgrowth requires the enlargement of the plasma membrane sustained by the exocytosis of specific vesicles. The well known, slow canonical form of outgrowth induced in pheochromocytoma PC12 cells by NGF, as well as the outgrowth taking place in neurons, involve vesicles positive for the vSNARE Ti ...
Rosalba D’Alessandro +2 more
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Controlling neurite outgrowth with patterned substrates [PDF]
Journal of Biomedical Materials Research Part A, 2011 AbstractIn vivo, neurons form neurites, one of which develops into the axon while others become dendrites. While this neuritogenesis process is well programmed in vivo, there are limited methods to control the number and location of neurite extension in vitro.
In Hong, Yang +2 more
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Clutching at Guidance Cues: The Integrin–FAK Axis Steers Axon Outgrowth
Biology, 2023 Integrin receptors are essential contributors to neurite outgrowth and axon elongation. Activated integrins engage components of the extracellular matrix, enabling the growth cone to form point contacts, which connect the extracellular substrate to ...
Mathew Davis-Lunn +2 more
doaj +1 more source
, 2011 Graphene has been demonstrated in many biomedical applications and its potentials for neural interfacing. Emerging concerns on graphene, as a biomedical material, are its biocompatibility and how biologically targeted tissue/cells respond to it ...
Tang, ML (reprint author), Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, 398 Ruoshui Rd, Suzhou Ind Pk 215123, Peoples R China +10 more
core +2 more sources
Biology Open, 2014 Small GTPase Rab35 is an important molecular switch for endocytic recycling that regulates various cellular processes, including cytokinesis, cell migration, and neurite outgrowth. We previously showed that active Rab35 promotes nerve growth factor (NGF)-
Hotaka Kobayashi +3 more
doaj +1 more source
Chimeric ZHHH neuroglobin acts as a cell membrane‐penetrating inducer of neurite outgrowth
FEBS Open Bio, 2017 Neuroglobin (Ngb) is a heme protein expressed in the vertebrate brain. We previously engineered a chimeric Ngb protein, in which module M1 of human Ngb is replaced by that of zebrafish Ngb, and showed that the chimeric ZHHH Ngb has a cell membrane ...
Nozomu Takahashi +3 more
doaj +1 more source
Neurite Outgrowth-Promoting Compounds from Cockscomb Hydrolysate
, 2022 Cockscomb hydrolysate was found to have neurite outgrowth-promoting activity in PC12 cells. To investigate the neurite outgrowth-promoting compounds derived from cockscomb hydrolysate, bioassay-guided purification was carried out.
Takeru Koga, Akihiro Tai
core +1 more source
Journal of Pharmacological Sciences, 2003 : The mechanism to enhance nerve growth factor (NGF, 2 ng/ml)-induced neurite outgrowth from PC12D cells by nardosinone isolated from Nardostachys chinensis was examined.
Ping Li +4 more
doaj +1 more source