Results 31 to 40 of about 87,065 (293)
Activity-dependent neurite outgrowth is a highly complex, regulated process with important implications for neuronal circuit remodeling in development as well as in seizure-induced sprouting in epilepsy.
Sarah M Wilson +7 more
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Tropomodulins are negative regulators of neurite outgrowth [PDF]
Regulation of the actin cytoskeleton is critical for neurite formation. Tropomodulins (Tmods) regulate polymerization at actin filament pointed ends. Previous experiments using a mouse model deficient for the neuron specific isoform Tmod2 suggested a role for Tmods in neuronal function by impacting processes underlying learning and memory. However, the
Fath, T. +4 more
openaire +3 more sources
Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells
Donepezil is a potent and selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer’s disease. To elucidate whether donepezil causes neuronal differentiation, we examined its effect on nerve growth factor (NGF)-induced neurite ...
Toru Oda +5 more
doaj +1 more source
Nerve growth factor (NGF) binds to TrkA and forms a NGF/TrkA complex at the cell surface, which is then internalized into signaling endosomes and promotes neuronal survival and neurite outgrowth.
Yao-yao QI +5 more
doaj +1 more source
CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. [PDF]
Electrical stimulation (ES)-triggered up-regulation of brain-derived neurotrophic factor (BDNF) and neurite outgrowth in cultured rat postnatal dorsal root ganglion neurons (DRGNs) is calcium (Ca2+)-dependent.
Xiaodong Yan +7 more
doaj +1 more source
Background: Neurite outgrowth is an important process in neural reorganization and repair after neuronal injury. Neurite outgrowth is one of the important mechanisms to maintain normal physiological neuronal function.
Varaporn Rakkhitawatthana +4 more
doaj +1 more source
Automated Screening of Neurite Outgrowth
Outgrowth of neurites in culture is used for assessing neurotrophic activity. Neurite measurements have been performed very slowly using manual methods or more efficiently with interactive image analysis systems. In contrast, medium-throughput and noninteractive image analysis of neurite screens has not been well described.
Peter, Ramm +5 more
openaire +2 more sources
Synthesis, biological evaluation and surface applications of neuritogenic compounds [PDF]
: This thesis is divided into five main chapters which all lay their focus on controlling neuronal cell differentiation using the tools of chemical biology.
Burch, Patrick
core +1 more source
The increasing intensity of environmental radiofrequency electromagnetic fields (RF-EMF) has increased public concern about its health effects. Of particular concern are the influences of RF-EMF exposure on the development of the brain. The mechanisms of
Chunhai Chen +22 more
doaj +1 more source
Rivastigmine (Riv) is a potent and selective cholinesterase (acetylcholinesterase, AChE and butyrylcholinesterase, BuChE) inhibitor developed for the treatment of Alzheimer's disease (AD).
Kazuki Terada +9 more
doaj +1 more source

