Results 31 to 40 of about 87,065 (293)

The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth

open access: yesFrontiers in Cellular Neuroscience, 2014
Activity-dependent neurite outgrowth is a highly complex, regulated process with important implications for neuronal circuit remodeling in development as well as in seizure-induced sprouting in epilepsy.
Sarah M Wilson   +7 more
doaj   +1 more source

Tropomodulins are negative regulators of neurite outgrowth [PDF]

open access: yesEuropean Journal of Cell Biology, 2011
Regulation of the actin cytoskeleton is critical for neurite formation. Tropomodulins (Tmods) regulate polymerization at actin filament pointed ends. Previous experiments using a mouse model deficient for the neuron specific isoform Tmod2 suggested a role for Tmods in neuronal function by impacting processes underlying learning and memory. However, the
Fath, T.   +4 more
openaire   +3 more sources

Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells

open access: yesJournal of Pharmacological Sciences, 2007
Donepezil is a potent and selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer’s disease. To elucidate whether donepezil causes neuronal differentiation, we examined its effect on nerve growth factor (NGF)-induced neurite ...
Toru Oda   +5 more
doaj   +1 more source

Magnaporthe Rab5 homologs show distinct functions in nerve growth factor (NGF)-mediated neurite outgrowth and cell differentiation

open access: yesJournal of Integrative Agriculture, 2015
Nerve growth factor (NGF) binds to TrkA and forms a NGF/TrkA complex at the cell surface, which is then internalized into signaling endosomes and promotes neuronal survival and neurite outgrowth.
Yao-yao QI   +5 more
doaj   +1 more source

CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. [PDF]

open access: yesPLoS ONE, 2016
Electrical stimulation (ES)-triggered up-regulation of brain-derived neurotrophic factor (BDNF) and neurite outgrowth in cultured rat postnatal dorsal root ganglion neurons (DRGNs) is calcium (Ca2+)-dependent.
Xiaodong Yan   +7 more
doaj   +1 more source

Effect of Thai medicinal plants Acanthus ebracteatus Vahl. Carthamus tinctorius L. and Streblus asper Lour. on neurite outgrowth activity in Neuro-2A cells

open access: yesJournal of Associated Medical Sciences, 2023
Background: Neurite outgrowth is an important process in neural reorganization and repair after neuronal injury. Neurite outgrowth is one of the important mechanisms to maintain normal physiological neuronal function.
Varaporn Rakkhitawatthana   +4 more
doaj   +1 more source

Automated Screening of Neurite Outgrowth

open access: yesSLAS Discovery, 2003
Outgrowth of neurites in culture is used for assessing neurotrophic activity. Neurite measurements have been performed very slowly using manual methods or more efficiently with interactive image analysis systems. In contrast, medium-throughput and noninteractive image analysis of neurite screens has not been well described.
Peter, Ramm   +5 more
openaire   +2 more sources

Synthesis, biological evaluation and surface applications of neuritogenic compounds [PDF]

open access: yes, 2013
: This thesis is divided into five main chapters which all lay their focus on controlling neuronal cell differentiation using the tools of chemical biology.
Burch, Patrick
core   +1 more source

1800 MHz Radiofrequency Electromagnetic Field Impairs Neurite Outgrowth Through Inhibiting EPHA5 Signaling

open access: yesFrontiers in Cell and Developmental Biology, 2021
The increasing intensity of environmental radiofrequency electromagnetic fields (RF-EMF) has increased public concern about its health effects. Of particular concern are the influences of RF-EMF exposure on the development of the brain. The mechanisms of
Chunhai Chen   +22 more
doaj   +1 more source

Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.

open access: yesPLoS ONE, 2018
Rivastigmine (Riv) is a potent and selective cholinesterase (acetylcholinesterase, AChE and butyrylcholinesterase, BuChE) inhibitor developed for the treatment of Alzheimer's disease (AD).
Kazuki Terada   +9 more
doaj   +1 more source

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