Results 141 to 150 of about 4,357 (193)
Some of the next articles are maybe not open access.
Oral contraceptives and neuroactive steroids
Pharmacology Biochemistry and Behavior, 2006A deregulation in the peripheral and brain concentrations of neuroactive steroids has been found in certain pathological conditions characterized by emotional or affective disturbances, including major depression and anxiety disorders. In this article we summarize data pertaining to the modulatory effects of oral contraceptive treatment on neuroactive ...
Giovanni Biggio, A Concas
exaly +5 more sources
Neuroactive steroids and seizure susceptibility
Epilepsy Research, 2001There is increasing clinical and experimental evidence that hormones, in particular sex steroid hormones, influence neuronal excitability and other brain functions. The term 'neuroactive steroids' has been coined for steroids that interact with neurotransmitter receptors.
Birgit Stoffel-Wagner +2 more
exaly +3 more sources
Neuroactive steroids and PTSD treatment
Neuroscience Letters, 2017This review highlights early efforts to translate pre-clinical and clinical findings regarding the role of neuroactive steroids in stress adaptation and PTSD into new therapeutics for PTSD. Numerous studies have demonstrated PTSD-related alterations in resting levels or the reactivity of neuroactive steroids and their targets.
Ann M Rasmusson +2 more
exaly +3 more sources
Neuroactive Steroids and Neuroinflammation
, 2016 Neuroinflammatory condition is a common characteristic shared by different neurodegenerative diseases. To date, therapeutic interventions able to stop neuroinflammation and promote repair is still lacking. Neuroactive steroids are cholesterol-derived molecules that exert their functions acting on the central nervous system.
Giatti S., Melcangi R. C.
openaire +2 more sources
Neuroactive steroids as modulators of depression and anxiety
Expert Review of Endocrinology & Metabolism, 2006 In addition to the well-known genomic effects of steroid molecules, certain neuroactive steroids control neurotransmission through the modulation of specific neurotransmitter receptors. Preclinical studies suggested that neuroactive steroids may modulate anxiety and depression-related behavior and may contribute to the therapeutic effects of ...
Daniela, Eser +5 more
openaire +3 more sources
Neuroactive steroids and peripheral myelin proteins
Brain Research Reviews, 2001 The present review summarizes observations obtained in our laboratories which underline the importance of neuroactive steroids (i.e., progesterone (PROG), dihydroprogesterone (5alpha-DH PROG), tetrahydroprogesterone (3alpha, 5alpha-TH PROG), testosterone (T), dihydrotestosterone (DHT) and 5alpha-androstan-3alpha,17beta-diol (3alpha-diol)) in the ...
V. Magnaghi +4 more
openaire +3 more sources
Neuroactive steroids: new biomarkers of cognitive aging
Journal of Steroid Biochemistry and Molecular Biology, 2003 International audienceIntensive studies in animals established that neuroactive steroids display neuronal actions and influence behavioral functions. We describe here investigations on the role of neuroactive steroids in learning and memory processes ...
Monique Vallée +2 more
exaly +2 more sources
The FASEB Journal, 1992
Neuroactive steroids are natural or synthetic steroids that rapidly alter the excitability of neurons by binding to membrane‐bound receptors such as those for inhibitory and (or) excitatory neurotransmitters. The best‐studied neuroactive steroids are a series of sedative‐hypnotic 3 α ‐hydroxy
S M, Paul, R H, Purdy
openaire +2 more sources
Neuroactive steroids are natural or synthetic steroids that rapidly alter the excitability of neurons by binding to membrane‐bound receptors such as those for inhibitory and (or) excitatory neurotransmitters. The best‐studied neuroactive steroids are a series of sedative‐hypnotic 3 α ‐hydroxy
S M, Paul, R H, Purdy
openaire +2 more sources
Neuroactive Steroids and Ethanol
Alcoholism: Clinical and Experimental Research, 2005This article presents the proceedings of a symposium presented at the International Society for Biomedical Research on Alcoholism 12th World Congress on Biomedical Alcohol Research, held in Heidelberg/Mannheim, Germany, from September 29 to October 2, 2004. The organizer and chairperson was Robert H. Purdy.
Robert H, Purdy +5 more
openaire +2 more sources
Neuropsychopharmacology, 2005 There is evidence that both cerebrospinal fluid (CSF) and plasma concentrations of 3 alpha-reduced neuroactive steroids are decreased in major depressive disorder.
Cornelius Schule +2 more
exaly +2 more sources