Results 191 to 200 of about 362,652 (233)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Flavonoids and phenolic compounds: a promising avenue for neurodegenerative disease therapy. [PDF]

Turk J Biol
Şahin TÖ, Cemali Ö, Özdemir M, Ayten Ş, Ağagündüz D.   +4 more
europepmc   +1 more source

Noradrenergic therapies in neurodegenerative disease: from symptomatic to disease modifying therapy? [PDF]

Brain Commun
Durcan R, O'Callaghan C, Rowe JB.
europepmc   +1 more source

HDACs in the Brain: From Chromatin Remodeling to Neurodegenerative Disease. [PDF]

Cells
Diniz LP, Pinheiro PSM, Franco LS, Gomes FCA.   +3 more
europepmc   +1 more source

Mitochondrial DNA Instability and Neuroinflammation: Connecting the Dots Between Base Excision Repair and Neurodegenerative Disease. [PDF]

Genes (Basel)
Pittman MN, Nelsen MB, Thompson MK, Prakash A.   +3 more
europepmc   +1 more source

Regional and Socioeconomic Disparities in Frailty Across Tasmania: Evidence From Island Study Linking Ageing and Neurodegenerative Disease. [PDF]

Australas J Ageing
Lou Z, Roccati E, Alty JE, Callisaya ML, Vickers JC, Gordon EH, Hubbard RE, Ward DD.   +7 more
europepmc   +1 more source