Results 171 to 180 of about 636,708 (294)

Beyond prion-like spreading in neurodegenerative disease. [PDF]

Alzheimers Dement
Meisl G, Rowe JB, Klenerman D.
europepmc   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Transsaccadic working memory in healthy ageing and neurodegenerative disease. [PDF]

Elife
Zhao S, Parr T, Udale R, Klar V, Davis Jones G, Scholcz A, Toniolo S, Manohar SG, Husain M.   +8 more
europepmc   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Design Strategies and Emerging Applications of High‐Performance Flexible Piezoresistive Pressure Sensors

Advanced Functional Materials, EarlyView.
Flexible piezoresistive pressure sensors underpin wearable and soft electronics. This review links sensing physics, including contact resistance modulation, quantum tunneling and percolation, to unified materials/structure design. We highlight composite and graded architectures, interfacial/porous engineering, and microstructured 3D conductive networks
Feng Luo, Artur Ciesielski, Paolo Samorì   +2 more
wiley   +1 more source

The Fragile Balance: Autophagy's Role in Neurodegenerative Disease Progression. [PDF]

Curr Neuropharmacol
Bhushan B, Dhanawat M, Garima, Wilson K, Gupta S, Chauhan S.   +5 more
europepmc   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Artificial Intelligence in Neuro-Ophthalmology for Optic Disc Pathologies and Neurodegenerative Disease. [PDF]

Eye Brain
Ahuja AS, Paredes Iii AA, Eisel MLS, Miller C, Truong N, Falardeau J.   +5 more
europepmc   +1 more source

Rev-erbs and glia—implications for neurodegenerative diseases [PDF]

, 2019
Dimitry, Julie M., Griffin, Percy, Musiek, Erik S.   +2 more
core   +1 more source