Results 151 to 160 of about 5,310,608 (313)
Biometals in neurodegenerative diseases : mechanisms and therapeutics /
, 2017 Cover; Title page; Copyright page; Contents; Contributors; Preface; Chapter 1 -- Biometals and Alzheimer's Disease; Introduction; The Role of Copper in AD; The Role of Zinc in AD; The Role of Iron in AD; Therapeutic Targeting of Biometals in AD ...
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Selected neurodegenerative disease and their therapeutic approaches.
, 2020 This thesis is about neurodegenerative diseases, which is debilitating and incurable, I focused on Alzheimer’s and Parkinson’s diseases which are the most prevalent, affecting millions of people around the globe.
Abdulrasheed, Fatima Alimi
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microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities, and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification.
Sung‐A Kim +2 more
wiley +1 more source
Neurobiology Research on Neurodegenerative Disorders
The aim of the following Special Issue was to call for research in the field of neurodegenerative disorders (NDDs) [...
Grażyna Lietzau
core +1 more source
The activity of amyloid beta binding alcohol dehydrogenase in Alzheimer's disease [PDF]
, 2012 The mitochondria are a vibrant hub for many problems that occur in Alzheimer’s disease. The enzyme amyloid-ß binding alcohol dehydrogenase (ABAD) and Cyclophilin D (CypD) are two key mitochondrial proteins that have essential functions in Alzheimer’s ...
Allen, Zoe Eleanor
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Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
Advanced Functional Materials, EarlyView.A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Neurotensin as Modulator of Glutamatergic Signalling: Relevance in Neurodegenerative Diseases
, 2009 Rationale: Neurotensin (NT) is a tridecapeptide widely distributed in mammalian brain, where acts as a neurotransmitter or neuromodulator of classical neurotransmitters, mainly through the activation of its receptor NTS1.
Mazza, Roberta
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Identification and evaluation of biomarkers for Huntington’s disease [PDF]
, 2009 Huntington’s disease (HD) is a devastating, incurable inherited neurodegenerative disorder that commonly affects adults in mid-life. Despite encouraging results from in vitro and animal trials, disease-modifying therapeutic trials in HD are limited by ...
Wild, E.J.
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Advanced Functional Materials, EarlyView.A sequential dual‐alignment strategy independently programs the orientation of conductive metal‐organic framework (c‐MOF) microrods and liquid crystals within a composite film. This approach creates an asymmetric bilayer structure that enables precise, multi‐responsive actuation.
Taegyun Hong +5 more
wiley +1 more source