Results 291 to 300 of about 9,572,367 (390)

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Editorial: Non-neuronal cells in neurodegenerative diseases and psychiatric disorders. [PDF]

Front Cell Neurosci
Estudillo E, Pérez-Sánchez G, Pavón L, Jiménez A.   +3 more
europepmc   +1 more source

5.Cellular transplantation for neurodegenerative diseases

, 2001
Douglas Kondziolka, Lawrence R. Wechsler, Carolyn C. Meltzer, Christian Achim   +3 more
openalex   +2 more sources

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Amyotrophic lateral sclerosis and neurodegenerative diseases: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lei C, Chen J, Chen Z, Xiao Y, Chen J, Ma C, Yang M, Wu D, Xie L.   +8 more
europepmc   +1 more source

Abstracts from the 1st International Conference on Alzheimer's disease and Related Neurodegenerative Disorders Wuhan, China

, 2002
Khalid Iqbal, Alejandra del C. Alonso, Chang Gong, Niloufar Haque, S. Khatoon, Juan Pei, A. Sengupta, Ichiro Tsujio, Jiebiao Wang, Inge Grundke‐Iqbal, Mamoru Takeda, George Perry, Rudolph J. Castellani, Peggy L.R. Harris, Sandra L. Siedlak, Mariarosaria Taddeo, Akihiko Nunomura, Hisashi Fujioka, Mark A. Smith, Abha Chauhan, Ved Chauhan   +20 more
openalex   +2 more sources

New dimensions in palliative care: a palliative approach to neurodegenerative diseases and final illness in older people [PDF]

, 2003
Linda J. Kristjanson, Christine Toye, Sky Dawson   +2 more
openalex   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Airborne Cyanobacterial Toxins and Their Links to Neurodegenerative Diseases. [PDF]

Molecules
Morris ZJ, Stommel EW, Metcalf JS.
europepmc   +1 more source