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Epigenetics in Neurodegenerative Diseases
Healthy brain functioning requires a continuous fine-tuning of gene expression, involving changes in the epigenetic landscape and 3D chromatin organization. Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) are three multifactorial neurodegenerative diseases (NDDs) that are partially explained by genetics (Brigitte, van Zundert, Martin, Montecino
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Receptors in neurodegenerative diseases
Pharmaceutica Acta Helvetiae, 2000The ability of trophic factors to regulate developmental neuronal survival and adult nervous system plasticity suggests the use of these molecules to treat neurodegeneration associated with human diseases, such as Alzheimer's, Huntington's and Parkinson's disease, of amyotrophic lateral sclerosis and peripheral sensory neuropathies.
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Fluorescent Diagnostic Probes in Neurodegenerative Diseases
Advanced Materials, 2020Jin Zhou, Paramesh Jangili, Subin Son
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NDDRF: A risk factor knowledgebase for personalized prevention of neurodegenerative diseases
Journal of Advanced Research, 2022Cheng Bi, Shengrong Zhou, Manhong Shi
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Prion-like transmission of protein aggregates in neurodegenerative diseases
Nature Reviews Molecular Cell Biology, 2010Patrik Brundin +2 more
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Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases
Nature Reviews Drug Discovery, 2011Daniel W Neef +2 more
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Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
Nature Medicine, 2014Jing L Guo +2 more
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