Results 31 to 40 of about 581,379 (326)
Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2014 [PDF]
, 2015 Epidemiological studies suggest that high dietary intake of phytochemicals and in particular of polyphenols is associated with decreased risk of a multitude of diseases states including cardiovascular disease, cancer, and neurodegenerative diseases.
Angeloni, Cristina +3 more
core +5 more sources
Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress [PDF]
, 2014 Accepted: 8 January 2014 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acknowledgments
Alfonso, Amparo +9 more
core +4 more sources
Regulation of Mitochondrial Dynamics and Neurodegenerative Diseases [PDF]
, 2011 Mitochondria are important cellular organelles in most metabolic processes and have a highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance between fission and fusion plays critical roles in mitochondrial functions. In recent
Fujimura, Atsushi +6 more
core +1 more source
Anti-aggregant tau mutant promotes neurogenesis
Molecular Neurodegeneration, 2017 Background The microtubule-associated protein Tau plays a role in neurodegeneration as well as neurogenesis. Previous work has shown that the expression of the pro-aggregant mutant Tau repeat domain causes strong aggregation and pronounced neuronal loss ...
Maria Joseph +4 more
doaj +1 more source
Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease [PDF]
, 2019 The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs.
Antonella Amato +2 more
core +1 more source
Neurodegenerative Disease Tauopathies
Annual Review of Pathology: Mechanisms of DiseaseTauopathies are a diverse group of progressive and fatal neurodegenerative diseases characterized by aberrant tau inclusions in the central nervous system. Tau protein forms pathologic fibrillar aggregates that are typically closely associated with neuronal cell death, leading to varied clinical phenotypes including dementia, movement disorders, and ...
Creekmore, Benjamin C. +2 more
openaire +2 more sources
Nuclear Receptors as Therapeutic Targets for Neurodegenerative Diseases: Lost in Translation [PDF]
, 2019 Neurodegenerative diseases are characterized by a progressive loss of neurons that leads to a broad range of disabilities, including severe cognitive decline and motor impairment, for which there are no effective therapies.
Codocedo, Juan F. +3 more
core +1 more source
Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]
, 2015 Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C +9 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Alzheimer’s Research & Therapy, 2018 Background Neuroinflammation has gained increasing attention as a potential contributing factor in Alzheimer’s disease (AD) pathology. A clinical cerebrospinal fluid biomarker capable of monitoring this process during the course of the disease has yet to
Frederic Brosseron +7 more
doaj +1 more source