Results 11 to 20 of about 348,117 (269)
Aquaporins and Neurodegenerative Diseases [PDF]
Current Neuropharmacology, 2010 Aquaporins (AQPs) are a family of widely distributed membrane-inserted water channel proteins providing a pathway for osmotically-driven water, glycerol, urea or ions transport through cell membranes and mechanisms to control particular aspects of homeostasis.
Foglio E, RODELLA, Luigi Fabrizio
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Epilepsy in neurodegenerative diseases
Epileptic Disorders, 2022 AbstractAlthough epilepsy as a comorbidity in neurodegenerative disorders is increasingly recognized, its incidence is still underestimated and the features of epilepsy in the different neurodegenerative conditions are still poorly defined. Improved health care, resulting in increased longevity, will unavoidably lead to an increment of epilepsy cases ...
Neri, Sabrina +4 more
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Mitoepigenetics and Neurodegenerative Diseases [PDF]
Frontiers in Endocrinology, 2019 Mitochondrial impairment and increased oxidative stress are common features in neurodegenerative disorders, leading researchers to speculate that epigenetic changes in the mitochondrial DNA (mitoepigenetics) could contribute to neurodegeneration.
Coppede F., Stoccoro A.
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Advances in Neurodegenerative Diseases
Neurology International, 2022 A multitude of diseases presenting a wide variety of phenotypic appearances are included in neurodegenerative disorders [...]
Vasileios Siokas, Efthimios Dardiotis
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Biomarkers in Neurodegenerative Diseases [PDF]
Biomedicines, 2022 An increasing number of people are affected by various neurodegenerative diseases each year, impacting the quality of life of millions of people worldwide [...]
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TREM2 in Neurodegenerative Diseases [PDF]
Molecular Neurodegeneration, 2017 TREM2 variants have been identified as risk factors for Alzheimer's disease (AD) and other neurodegenerative diseases (NDDs). Because TREM2 encodes a receptor exclusively expressed on immune cells, identification of these variants conclusively demonstrates that the immune response can play an active role in the pathogenesis of NDDs.
Jay, Taylor R. +2 more
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The lysosome and neurodegenerative diseases [PDF]
Acta Biochimica et Biophysica Sinica, 2009 It has long been believed that the lysosome is an important digestive organelle. There is increasing evidence that the lysosome is also involved in pathogenesis of a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.
Lisha, Zhang, Rui, Sheng, Zhenghong, Qin
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Sphingolipids in neurodegenerative diseases
Frontiers in Neuroscience, 2023 Neurodegenerative Diseases (NDDs) are a group of disorders that cause progressive deficits of neuronal function. Recent evidence argues that sphingolipid metabolism is affected in a surprisingly broad set of NDDs. These include some lysosomal storage diseases (LSDs), hereditary sensory and autonomous neuropathy (HSAN), hereditary spastic paraplegia ...
Xueyang Pan +8 more
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Scientific Reports, 2022 Most current models of recognition memory fail to separately model item and person heterogeneity which makes it difficult to assess ability at the latent construct level and prevents the administration of adaptive tests.
Jeremie Güsten +3 more
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Caudo‐rostral brain spreading of α‐synuclein through vagal connections
EMBO Molecular Medicine, 2013 α‐Synuclein accumulation and pathology in Parkinson's disease typically display a caudo‐rostral pattern of progression, involving neuronal nuclei in the medulla oblongata at the earliest stages.
Ayse Ulusoy +6 more
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