Results 181 to 190 of about 470,350 (340)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Testicular inflammation in male reproductive system

Exploration of Immunology
The control of the immune system, neuroendocrine system, and energy metabolism is essential for the physiological process of male reproduction. The hypothalamic-pituitary-testicular (HPT) axis regulates the generation of gonadal steroid hormones in the ...
Prity Yadav, Pratap Chand Mali
doaj   +1 more source

Pancreatic neuroendocrine tumors

Intractable & Rare Diseases Research, 2017
Pancreatic neuroendocrine neoplasms (pNENs) are a heterogeneous group of tumors including well differentiated pancreatic neuroendocrine tumors (pNETs) and neuroendocrine carcinomas (pNECs). The incidence of pNENs has increased over the past few decades.
openaire   +3 more sources

Carbonyl reductase 4 suppresses colorectal cancer progression through the DNMT3B/CBR4/FASN/mTOR axis

Cancer Cell International
Lipid metabolism is implicated in the initiation and progression of human colorectal cancer (CRC). Carbonyl reductase 4 (CBR4), a member of the carbonyl reductase family, plays a role in the biosynthesis of fatty acids.
Jingjing Zhang, Tiaotiao Chen, Wencheng Wu, Chunhua Hu, Bangting Wang, Xiaofeng Jia, Mujie Ye   +6 more
doaj   +1 more source

Precision modulation of tumor excitability: Targeting cell phenotypic heterogeneity for next‐generation cancer therapy

BMEMat, EarlyView.
This Perspective introduces tumor electrical excitability as a previously overlooked dimension of cancer biology. It proposes that tumor–neural interactions enable malignant cells to acquire neuron‐like properties and form bidirectional chemical and electrical communications with nerves.
Zonghao Liu, Xingwu Jiang, Gang Liu, Jian Chen, Kun Song, Xu Li, Siew Yee Wong, Ruicheng Shi, Yanyan Liu, Wenbo Bu   +9 more
wiley   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Sunitinib malate for the treatment of pancreatic neuroendocrine tumors.

New England Journal of Medicine, 2011
E. Raymond, L. Dahan, J. Raoul, Y. Bang, I. Borbath, C. Lombard-Bohas, J. Valle, P. Metrakos, Denis Smith, A. Vinik, Jen‐Shi Chen, D. Hörsch, P. Hammel, B. Wiedenmann, E. Van Cutsem, S. Patyna, D. Lu, C. Blanckmeister, R. Chao, P. Ruszniewski   +19 more
semanticscholar   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Whole-genome landscape of pancreatic neuroendocrine tumours

Nature, 2017
A. Scarpa, D. Chang, K. Nones, V. Corbo, A. Patch, Peter Bailey, R. Lawlor, A. Johns, David K. Miller, A. Mafficini, B. Rusev, M. Scardoni, D. Antonello, S. Barbi, K. Sikora, S. Cingarlini, C. Vicentini, S. McKay, M. Quinn, T. Bruxner, Angelika N. Christ, Ivon Harliwong, S. Idrisoglu, S. McLean, C. Nourse, Ehsan Nourbakhsh, P. J. Wilson, M. Anderson, L. Fink, F. Newell, N. Waddell, O. Holmes, S. Kazakoff, C. Leonard, S. Wood, Qinying Xu, Shivashankar H. Nagaraj, E. Amato, I. Dalai, S. Bersani, I. Cataldo, A. D. Dei Tos, P. Capelli, M. Davi’, L. Landoni, A. Malpaga, Marco Miotto, V. Whitehall, B. Leggett, Janelle L. Harris, Jonathan Harris, Marc D. Jones, J. Humphris, L. Chantrill, V. Chin, A. Nagrial, M. Pajic, C. Scarlett, Andreia V. Pinho, I. Rooman, C. Toon, Jianmin Wu, M. Pinese, M. Cowley, A. Barbour, A. Mawson, Emily S. Humphrey, E. Colvin, A. Chou, Jessica A. Lovell, N. Jamieson, F. Duthie, M. Gingras, W. Fisher, Rebecca A. Dagg, L. Lau, Michael Lee, H. Pickett, R. Reddel, J. Samra, J. Kench, N. Merrett, K. Epari, N. Nguyen, N. Zeps, M. Falconi, M. Simbolo, G. Butturini, G. Van Buren, S. Partelli, M. Fassan, K. Khanna, A. Gill, D. Wheeler, R. Gibbs, E. Musgrove, C. Bassi, G. Tortora, P. Pederzoli, J. Pearson, Nicola Waddell, A. Biankin, S. Grimmond   +102 more
semanticscholar   +1 more source