Multi-omics analysis constructs a novel neuroendocrine prostate cancer classifier and classification system. [PDF]
Shen J +9 more
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New insights into markers for distinguishing neuroendocrine prostate cancer: evidence from single-cell analysis. [PDF]
Luo H +6 more
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A highly sensitive screening system to evaluate the reversibility of neuroendocrine prostate cancer to prostate adenocarcinoma. [PDF]
Fukui T +13 more
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Identification of the specific characteristics of neuroendocrine prostate cancer: Immune status, hub genes and treatment. [PDF]
Wang J +8 more
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RB1 and p53 are diagnostic markers for treatment-related neuroendocrine prostate cancer: a clinical and pathological analysis of 23 cases. [PDF]
Zhang Y +5 more
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Immunogenomic Landscape of Neuroendocrine Prostate Cancer
Clinical Cancer Research, 2023Abstract Purpose: Patients with neuroendocrine prostate cancer (NEPC) are often managed with immunotherapy regimens extrapolated from small-cell lung cancer (SCLC). We sought to evaluate the tumor immune landscape of NEPC compared with other prostate cancer types and SCLC.
Bhavneet Bhinder +12 more
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Prostate Cancer and Neuroendocrine Differentiation
International Urology and Nephrology, 1999A retrospective study was conducted in 41 patients with adenocarcinoma of the prostate to investigate the correlation between pathological stage, Gleason score and neuroendocrine differentiation in order to evaluate the prognostic significance of neuroendocrine differentiation. Patients' ages ranged from 50 to 84 (mean 69.1) years. Clinical staging was
ÇELİK, BÜLENT +5 more
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Treatment Outcomes in Neuroendocrine Prostate Cancer
Anticancer Research, 2022Neuroendocrine prostate cancer (NEPC) is rare and has a poor prognosis; its clinical course and treatment outcomes are also unclear. This study investigated the clinical characteristics, clinical course, and treatment outcomes of patients with NEPC.This retrospective study investigated 14 patients histologically diagnosed with NEPC at Kanazawa ...
Hiroaki, Iwamoto +9 more
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Neuroendocrine Cells in Prostate Cancer
Critical Reviews in Eukaryotic Gene Expression, 2004Neuroendocrine (NE) cells are found in prostate tumors, and their incidence is considered a promising prognostic indicator for the development of androgen-independent disease. NE cells are derived from non-NE prostate cancer cells and secrete factors that can act in a paracrine manner to stimulate the survival, growth, motility, and metastatic ...
George P, Amorino, Sarah J, Parsons
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Neuroendocrine Target Therapies for Prostate Cancer
Urologia Journal, 2011It is important to determine whether an increase in Chromogranin A levels and neuroendocrine (NE) cell activation are associated with progression towards on hormone-independent prostate-cancer. We proposed a combination of estrogens and somatostatin analogues as therapy of NE activation in hormone-independent prostate cancer. The combined therapy with
SCIARRA, Alessandro +8 more
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