Results 51 to 60 of about 102,686 (380)

Metastasizing esthesioneuroblastoma in a dog [PDF]

, 2014
A 7-year-old Afghan hound presented with a history of disorientation, loss of vision, and seizures. Magnetic resonance imaging helped identify a mass at the level of the main olfactory bulb that compressed and displaced adjacent tissues in the cribriform
Herden, Christiane, Klingler, Melanie, Schmidt, Martin J., Siudak, Krystyna   +3 more
core   +1 more source

Alpha‐Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure

Annals of Neurology, 2021
To explore the role of alpha‐synuclein (αSyn) oligomers and neurofilament light chain (NfL) in cerebrospinal fluid (CSF) of patients with pure autonomic failure (PAF) as markers of future phenoconversion to multiple system atrophy (MSA).
W. Singer, A. Schmeichel, M. Shahnawaz, J. Schmelzer, D. Sletten, T. Gehrking, Jade A. Gehrking, A. D. Olson, Mariana D. Suarez, Pinaki Misra, C. Soto, P. Low   +11 more
semanticscholar   +1 more source

Age-dependent increase of cytoskeletal components in sensory axons in human skin

Frontiers in Cell and Developmental Biology, 2022
Aging is a complex process characterized by several molecular and cellular imbalances. The composition and stability of the neuronal cytoskeleton is essential for the maintenance of homeostasis, especially in long neurites.
Klara Metzner, Klara Metzner, Omar Darawsha, Mengzhe Wang, Nayana Gaur, Nayana Gaur, Yiming Cheng, Annekathrin Rödiger, Christiane Frahm, Otto W. Witte, Fabiana Perocchi, Fabiana Perocchi, Fabiana Perocchi, Hubertus Axer, Julian Grosskreutz, Julian Grosskreutz, Monika S. Brill, Monika S. Brill   +17 more
doaj   +1 more source

Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function

Cells, 2016
Intermediate filaments together with actin filaments and microtubules form the cytoskeleton, which is a complex and highly dynamic 3D network. Intermediate filaments are the major mechanical stress protectors but also affect cell growth, differentiation,
Nicole Schwarz, Rudolf E. Leube
doaj   +1 more source

Plasma neurofilament light chain protein is not increased in forensic psychiatric populations: a pilot study

Frontiers in Psychiatry, 2023
IntroductionNeurofilament light chain protein (NfL) is a fluid biomarker of neural injury measurable in cerebrospinal fluid and blood. Patients with different neurodegenerative disorders and mild traumatic brain injury display elevated levels of NfL ...
Anja Fernqvist, Anja Fernqvist, Eirini Alexiou, Eirini Alexiou, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Katarina Howner, Katarina Howner, Thomas Nilsson, Thomas Nilsson, Peter Andiné, Peter Andiné, Peter Andiné   +16 more
doaj   +1 more source

Neurofilament light as a biomarker in traumatic brain injury

Neurology, 2020
Objective To determine whether serum neurofilament light (NfL) correlates with CSF NfL, traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor imaging (DTI) estimates of traumatic axonal injury (TAI).
P. Shahim, Adam M. Politis, Andre J. van der Merwe, Brian Moore, Y. Chou, D. Pham, J. Butman, R. Diaz-Arrastia, J. Gill, D. Brody, H. Zetterberg, K. Blennow, L. Chan   +12 more
semanticscholar   +1 more source

Diagnostic biomarkers of multiple sclerosis [PDF]

Romanian Journal of Neurology, 2021
Multiple sclerosis (MS) is a chronic and inflammatory disease of the central nervous system (CNS) that is common in people between the ages of 20 and 40.
Mohammad Asgharzadeh, Mir Reza Valiallahzadeh, Zahra Taghinejad, Behroz Mahdavi Poor, Hossein Samadi Kafil, Vahid Asgharzadeh, Jalil Rashedi   +6 more
doaj   +1 more source

Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain

Brain Communications, 2022
The routine clinical integration of individualized objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development.
A. Thompson, E. Gray, Nick Verber, Y. Bobeva, V. Lombardi, Stephanie R Shepheard, O. Yildiz, E. Feneberg, Lucy Farrimond, T. Dharmadasa, Pamela Gray, E. Edmond, J. Scaber, Delia Gagliardi, J. Kirby, Thomas Jenkins, P. Fratta, C. Mcdermott, S. Manohar, K. Talbot, A. Malaspina, P. Shaw, M. R. Turner   +22 more
semanticscholar   +1 more source

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium [PDF]

, 2020
Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Broglio, Steven P., Brooks, M. Alison, Cameron, Kenneth L., Campbell, Darren E., CARE Consortium Investigators, DiFiori, Jon, Duma, Stephan, Foroud, Tatiana, Gill, Jessica, Giza, Christopher C., Goldman, Joshua, Guskiewicz, Kevin, Harezlak, Jaroslaw, Houston, Megan N., Huber, Daniel L., Jackson, Jonathan C., Katz, Barry P., McAllister, Thomas W., McCrea, Michael, McGinty, Gerald, Meier, Timothy B., Mihalik, Jason, Nelson, Lindsay D., Pasquina, Paul, Rowson, Steven, Saykin, Andrew J., Svoboda, Steven J.   +26 more
core   +1 more source

Comparison of neurofilament light and heavy chain in spinal muscular atrophy and amyotrophic lateral sclerosis: A pilot study

Brain and Behavior, 2023
Background Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) were two major motor neuron diseases with similar symptoms and poor outcomes.
Jin‐Yue Li, Yi Dai, Xiao‐Han Sun, Hai‐tao Ren, Dong‐chao Shen, Xun‐Zhe Yang, Ming‐Sheng Liu, Li‐Ying Cui   +7 more
doaj   +1 more source