Results 141 to 150 of about 253,178 (331)

Neuroinflammation Induction and Alteration of Hippocampal Neurogenesis in Mice Following Developmental Exposure to Gossypol [PDF]

, 2020
Xiaoyan Zhu, Yongji Wu, Jiarong Pan, Cixia Li, Jian Huang, Enhui Cui, Ziluo Chen, Wentai Zhou, Xuejun Chai, Shanting Zhao   +9 more
openalex   +1 more source

Variant Update on ASCC1: Characterization of the First Homozygous Missense Variant Involved in Prenatal‐Onset Spinal Muscular Atrophy With Congenital Bone Fractures 2

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Spinal muscular atrophy with congenital bone fractures 2 is a rare and severe autosomal recessive neuromuscular disorder caused by pathogenic variants in ASCC1. This condition characterized by prenatal onset of severe hypotonia with fetal hypokinesia and congenital contractures results in arthrogryposis multiplex congenita, and increased ...
A. Civit, L. Kerbellec, D. Laurenceau, D. C. Ung, M. P. Moizard, N. Ronce, P. Gueguen, F. Laumonnier, A. C. Bréhin, F. Marguet, A. Laquerrière, A. M. Bergemer Fouquet, J. Cirier, S. Blesson, S. Arpin, M. Jeanne, M. L. Vuillaume   +16 more
wiley   +1 more source

Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis [PDF]

, 2018
Jeremy Hill, Viviana Zuluaga‐Ramirez, Sachin Gajghate, Malika Winfield, Yuri Persidsky   +4 more
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Blast-induced hearing loss suppresses hippocampal neurogenesis and disrupts long term spatial memory

, 2020
Senthilvelan Manohar, Henry J. Adler, Guang‐Di Chen, Richard Salvi   +3 more
openalex   +2 more sources

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source

Exploratory analysis of epileptic and non-epileptiform hippocampal network organization across spatial and frequency domains

NeuroImage
Understanding how epileptic networks may disrupt information processing requires examining the spatial organization of functional connectivity. Here, we present an exploratory case-series analysis of stereotactic EEG (SEEG) recordings from seven ...
Gadi Goelman, Zvi Israel, Sami Heymann, Dana Ekstein, Tal Benoliel   +4 more
doaj   +1 more source

High hopes for CB₂ receptors in neurogenesis [PDF]

, 2013
Eric J. Downer
openalex   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]

, 2014
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S., Golalipour, M.J., Kafshgiri, S.K.   +2 more
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