Results 141 to 150 of about 218,517 (358)

L-Lactate Promotes Adult Hippocampal Neurogenesis

Frontiers in Neuroscience, 2019
Neurogenesis, the formation of new neurons in the adult brain, is important for memory formation and extinction. One of the most studied external interventions that affect the rate of adult neurogenesis is physical exercise.
Yaeli Lev-Vachnish, Yaeli Lev-Vachnish, Yaeli Lev-Vachnish, Sharon Cadury, Sharon Cadury, Sharon Cadury, Aviva Rotter-Maskowitz, Aviva Rotter-Maskowitz, Aviva Rotter-Maskowitz, Noa Feldman, Noa Feldman, Noa Feldman, Asael Roichman, Tomer Illouz, Tomer Illouz, Alexander Varvak, Raneen Nicola, Raneen Nicola, Ravit Madar, Ravit Madar, Ravit Madar, Eitan Okun, Eitan Okun, Eitan Okun   +23 more
doaj   +1 more source

Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. [PDF]

, 2019
The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner.
An, Qin, Fan, Guoping, Hu, Youjin, Liu, Qinghuai, Mao, Xiying, Wang, Jinmei, Xi, Huiyu, Yang, Xian-Jie, Yuan, Songtao, Zhang, Xiangmei   +9 more
core  

Two New Cases Expand the Phenotypic Spectrum of TUBG1 Missense Variants

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The gamma‐tubulin ring complex (γ‐TuRC) plays a role in coordinating centrosome and spindle pole body formation during cell division. TUBG1 encodes a critical component of the γ‐TuRC. Pathogenic TUBG1 variants can cause a range of alterations in cortical gyral patterning, microcephaly, and other neurological manifestations.
Roser Urreizti, Jessica Vissicchio, Mohamed Idries, Monica Cozar, Raquel Rabionet, Tyhiesia Donald, Elizabeth J. Bhoj, Tomoki T. Nomakuchi, Shannon C. Shipley, Andrew E. Timms, Ghayda M. Mirzaa, Mercedes Serrano, Andrew K. Sobering   +12 more
wiley   +1 more source

Alzheimer’s disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms

Frontiers in Neuroscience, 2016
New neurons incorporate into the granular cell layer of the dentate gyrus throughout life. Neurogenesis is modulated by behavior and plays a major role in hippocampal plasticity.
Orly eLazarov, Carolyn eHollands, Nancy eBartolotti   +2 more
doaj   +1 more source

Neurogenesis in the aging brain

Clinical Interventions in Aging, 2008
Neurogenesis, or the birth of new neural cells, was thought to occur only in the developing nervous system and a fixed neuronal population in the adult brain was believed to be necessary to maintain the functional stability of adult brain circuitry. However, recent studies have demonstrated that neurogenesis does indeed continue into and throughout ...
Veronica Galvan, Kunlin Jin
openaire   +5 more sources

What is the functional role of adult neurogenesis in the hippocampus? [PDF]

, 2004
The dentate gyrus is part of the hippocampal memory system and special in that it generates new neurons throughout life. Here we discuss the question of what the functional role of these new neurons might be.
Kempermann, Gerd, Rasch, Malte J., Wiskott, Laurenz   +2 more
core   +1 more source

Phenotypic Characterization of Seven Pediatric Patients Diagnosed With KAT6B‐Related Disorders: Case Series and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione, Antonio Pizzuti, Gioia Mastromoro, Eleonora Cresta, Paola Favata, Maria Cristina Digilio, Rossella Capolino, Maria Lisa Dentici, Lorenzo Sinibaldi, Antonio Novelli, Marco Tartaglia, Gianluca Terrin, Viviana Cardilli   +12 more
wiley   +1 more source

Exposure to Patterned Auditory Stimuli during Acute Stress Prevents Despair-Like Behavior in Adult Mice That Were Previously Housed in an Enriched Environment in Combination with Auditory Stimuli

Neural Plasticity, 2018
Several interventions have been shown to counteract the effects of stress that may be related to improved neuroplasticity and neuronal activation. In this sense, environmental enrichment (ENR) protects against acute stress and increases neuroplasticity ...
Enrique Flores-Gutiérrez, Edith Araceli Cabrera-Muñoz, Nelly Maritza Vega-Rivera, Leonardo Ortiz-López, Gerardo Bernabé Ramírez-Rodríguez   +4 more
doaj   +1 more source

Neurogenesis in Drosophila: Notch mapping function obscure [PDF]

, 1984
Michael Akam
openalex   +1 more source

Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis [PDF]

, 1991
Stefan Krauß, Terje Johansen, Vladimir Korzh, Anders Fjose   +3 more
openalex   +1 more source