Results 31 to 40 of about 131,833 (239)
Frontiers in Neuroscience, 2020 A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable of generating oligodendrocytes
Roberto Valcárcel-Martín +11 more
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Scientific Reports, 2023 Umbilical cord blood (UCB) transplantation shows proangiogenic effects and contributes to symptom amelioration in animal models of cerebral infarction.
Yasunori Yoshida +11 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Neural Plasticity, 2018 Neurogenesis in the hippocampus is influenced by several factors including external stimuli. In addition to their involvement in learning and memory processes, newborn neurons of the dentate gyrus (DG) buffer against the effects of stress.
Gerardo Bernabé Ramírez-Rodríguez +2 more
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Appetite for Neurogenesis [PDF]
Developmental Cell, 2017 Adult neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ) produce diverse olfactory bulb (OB) neurons. In a recent paper in Science, Paul et al. (2017) show that hypothalamic propiomelanocortin (POMC) neurons innervate the anterior ventral V-SVZ and regulate deep granule interneuron production depending on feeding behavior.
Kristen L, Zuloaga, Sally, Temple
openaire +2 more sources
Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction
Advanced Functional Materials, EarlyView.Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch +13 more
wiley +1 more source
Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome
Frontiers in Cell and Developmental Biology, 2020 Hippocampal neurogenesis, the process by which neural stem cells (NSCs) continuously generate new neurons in the dentate gyrus (DG) of most mammals including humans, is chiefly regulated by neuronal activity.
Soraya Martín-Suárez +6 more
doaj +1 more source
Neurogenesis and Epilepsy [PDF]
Epilepsia, 2010 Abstract Medial temporal lobe epilepsy (mTLE) is a common and often intractable form of epilepsy. Approximately 50 million people suffer from different epilepsies worldwide,1 30%–40% of whom may continue to have poorly controlled seizures despite therapy.2,3 Medial TLE is estimated to be the most common cause of intractable epilepsy in ...
Parent, Jack M., Kron, Michelle M.
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Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Regulation of Injury-Induced Neurogenesis by Nitric Oxide
Stem Cells International, 2012 The finding that neural stem cells (NSCs) are able to divide, migrate, and differentiate into several cellular types in the adult brain raised a new hope for restorative neurology.
Bruno P. Carreira +2 more
doaj +1 more source