Results 31 to 40 of about 253,178 (331)
eLife, 2023 The rubella virus can interfere with fetal brain development by infecting immune cells called microglia during pregnancy.
Ekaterina Epifanova, Laurent Nguyen
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Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition
Nature Communications, 2023 Within the chromatin, distal elements interact with promoters to regulate specific transcriptional programs. Histone acetylation, interfering with the net charges of the nucleosomes, is a key player in this regulation.
Mattia Zaghi +22 more
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Molecular mechanisms of neurogenic aging in the adult mouse subventricular zone [PDF]
, 2019 In the adult rodent brain, the continuous production of new neurons by neural stem/progenitor cells (NSPCs) residing in specialized neurogenic niches and their subsequent integration into pre-existing cerebral circuitries supports odour discrimination ...
Biagioni, Stefano +4 more
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Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
, 2020 Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
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The cell cycle–apoptosis connection revisited in the adult brain [PDF]
, 2005 Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
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Human Amniotic Fluid Cells Form Functional Gap Junctions with Cortical Cells
Stem Cells International, 2012 The usage of stem cells is a promising strategy for the repair of damaged tissue in the injured brain. Recently, amniotic fluid (AF) cells have received a lot of attention as an alternative source of stem cells for cell-based therapies.
Anna Jezierski +6 more
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Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
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Frontiers in Cellular Neuroscience, 2022 The adult neurogenic niches are complex multicellular systems, receiving regulatory input from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways. Within the niches, adult neural stem cells (aNSCs) generate astrocytic
Amber Penning +7 more
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Weak universality in sensory tradeoffs [PDF]
, 2016 For many organisms, the number of sensory neurons is largely determined during development, before strong environmental cues are present. This is despite the fact that environments can fluctuate drastically both from generation to generation and within ...
DeDeo, Simon, Marzen, Sarah
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Neurobiology of Disease, 2009 In recent years, GDNF has emerged as a protective and restorative agent in several models of neurodegeneration; however, the exact molecular mechanisms responsible for these effects are not yet fully understood. Here we examined the effects of astrocytes
Jagdeep K. Sandhu +8 more
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