Results 101 to 110 of about 4,868 (220)

Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract Dementia with Lewy bodies (DLB), a progressive neurodegenerative disease with heterogeneous clinical presentations, greatly impacts patients, caregivers, and society. Despite its frequency, diagnosing and treating DLB remains challenging. Advances in in vivo biomarker assays reflecting underlying pathology are improving disease identification,
Jennifer G. Goldman, Bradley F. Boeve, Douglas Galasko, John‐Paul Taylor, James E. Galvin, James B. Leverenz, Frederic Blanc, Glenda Halliday, Kejal Kantarci, Afina W. Lemstra, Iracema Leroi, Simon J. G. Lewis, Irene Litvan, Helen Medsger, John O'Brien, Sonja W. Scholz, Dag Aarsland, Manabu Ikeda, Ian McKeith, Angela Taylor   +19 more
wiley   +1 more source

Frequency of orthostatic hypotension in the Pooled Resource Open-Access ALS Clinical Trials database

Frontiers in Neurology
PurposeTo explore the frequency of orthostatic hypotension (OH) in a large sample of amyotrophic lateral sclerosis patients (ALS).MethodsFrom the PRO-ACT database, data of 1,240 ALS patients were analyzed, focusing on blood pressure and heart rate before
C. Quarracino, F. Capani, F. Capani, M. Otero-Losada, G. E. Rodríguez, S. Pérez-Lloret, S. Pérez-Lloret   +6 more
doaj   +1 more source

Comparison of Dysautonomia Across Species: Current Knowledge and Future Research Opportunities

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Primary dysautonomia is a complex and often fatal autonomic nervous system disease. This literature review consolidates information on dysautonomia across species. Electronic databases (PubMed, Google Scholar and the Equine Grass Sickness Fund website) were systematically searched for veterinary and human medical literature on the topic.
Callum N. Atkins, Caroline N. Hahn, Bruce C. McGorum   +2 more
wiley   +1 more source

Being Prodromal: Current Criteria in the Context of Isolated REM Sleep Behavior Disorder

Movement Disorders Clinical Practice, Volume 12, Issue 6, Page 828-834, June 2025.
ABSTRACT Background Isolated REM sleep behavior disorder (iRBD) indicates an early α‐synucleinopathy with approximately 90% of individuals pheno‐converting to Parkinson's disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA). Recently, prodromal disease definitions (pPD, pDLB, pMSA) have been introduced.
Anja Ophey, Sinah Röttgen, Julia Reichrath, Elke Kalbe, Gereon R. Fink, Michael Sommerauer   +5 more
wiley   +1 more source

Neurogenic orthostatic hypotension – management update and role of droxidopa

Therapeutics and Clinical Risk Management, 2015
Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Vijayan J, Sharma VK
doaj  

Effect of Acute Exposure to Hypergravity (Gx vs. Gz) on Dynamic Cerebral Autoregulation [PDF]

We examined the effects of 30 min of exposure to either +3G(sub x) or +3G(sub z) centrifugation on cerebrovascular responses to 800 head-up tilt (HUT) in 14 healthy individuals.
Bondar, R. L., Kassam, M. S., Picot, P. A., Rupert, A. H., Schlegel, T. T., Serrador, Jorge M., Stein, F., Wood, S. J.   +7 more
core   +1 more source

Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features

American Journal of Medicine Open
Background: Hypermobile Ehlers-Danlos syndrome (hEDS) affects multiple systems, but comprehensive evaluations of a larger sample of hEDS patients are lacking.
Peter Novak, MD, PhD, David M. Systrom, MD, Sadie P. Marciano, PA-C, Alexandra Witte, PA-C, Arabella Warren, MD, PhD, Donna Felsenstein, MD, Matthew P. Giannetti, MD, Matthew J. Hamilton, MD, Jennifer Nicoloro-SantaBarbara, PhD, Mariana Castells, MD, Khosro Farhad, MD, David M. Pilgrim, MD, William J. Mullally, MD, Mark C. Fishman, MD, Jeff M. Milunsky, MD, Aubrey Milunsky, MD, Joel Krier, MD   +16 more
doaj   +1 more source

Unobtrusive Detection of Simulated Orthostatic Hypotension and Supine Hypertension Using Ballistocardiogram and Electrocardiogram of Healthy Adults

IEEE Journal of Translational Engineering in Health and Medicine, 2018
Effective management of neurogenic orthostatic hypotension and supine hypertension (SH-OH) due autonomic failure requires a frequent and timely adjustment of medication throughout the day to maintain the blood pressure (BP) within the normal range, i.e.,
Isaac S. Chang, Narges Armanfard, Abdul Q. Javaid, Jennifer Boger, Alex Mihailidis   +4 more
doaj   +1 more source

Diagnosis and management of autonomic dysfunction in dementia syndromes [PDF]

, 2019
This is the final version. Available on open access from Springer via the DOI in this record.a) Purpose of review: Autonomic dysfunction is common the dementia, particularly in the Lewy body dementias.
Allan, LM
core   +1 more source

Multiple System Atrophy with Neurogenic Orthostatic Hypotension: A Multidisciplinary Collaborative Rehabilitation Case Report

Xiehe Yixue Zazhi
Multiple system atrophy (MSA) is a rare with its adult onset progressive neurodegenerative disease, which is clinically classified into parkinsonian (MSA-P) and cerebellar (MSA-C) subtypes based on the presenting motor phenotype.
ZHANG Yuhang, WANG Han, DING Rongjing
doaj   +1 more source