Results 191 to 200 of about 4,868 (220)

Management of Neurogenic Orthostatic Hypotension

Journal of the American Medical Directors Association, 2014
The burden of orthostatic hypotension (OH) on public health is a universally recognized enigmatic clinical condition that is associated with significant increases on morbidity and mortality rates, and can take a major toll on one's quality of life. Orthostatic hypotension is predictive of vascular deaths from acute myocardial infarction, strokes in the
Debbie Arbique   +3 more
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Insulin‐induced hypotension and neurogenic orthostatic hypotension

Neurology, 1986
Insulin-induced hypoglycemia induced a fall in blood pressure (BP) in patients with idiopathic orthostatic hypotension (IOH) and multiple system atrophy (MSA), but not in control subjects. Only in IOH was there a correlation between plasma norepinephrine (NE) levels and maintenance of BP during the test. The hypotension was not affected by pretreatment
R T, Brown   +3 more
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Neurogenic Orthostatic Hypotension

New England Journal of Medicine, 2008
615 A 65-year-old man reports a 6-month history of dizziness, light-headedness, weakness, and fatigue while upright. He takes no medication and has no personal or family history of neurologic disease. On physical examination, his supine blood pressure is 160/100 mm Hg, with a heart rate of 72 beats per minute; on standing, his blood pressure falls to ...
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Neurogenic orthostatic hypotension: chasing “the fall”

Postgraduate Medical Journal, 2008
Abstract Orthostatic hypotension (OH) is a frequently encountered problem affecting nearly 30% of the population aged more than 60 years. It can result from neurological and non-neurological derangements which compromise the perfusion of the brain in an erect posture. Neurogenic OH is a manifestation of autonomic failure.
D, Gupta, M D, Nair
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Neuropharmacologic Distinction of Neurogenic Orthostatic Hypotension Syndromes

Clinical Neuropharmacology, 2006
Neurogenic orthostatic hypotension (OH) characterizes pure autonomic failure (PAF), multiple system atrophy (MSA), and Parkinson disease (PD) with autonomic failure. We used neuropharmacologic probes that might distinguish these diseases based on loss of sympathetic noradrenergic nerves in PAF and PD + OH but not in MSA, and related the results to ...
Yehonatan, Sharabi   +6 more
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Orthostatic Hypotension

Archives of Internal Medicine, 1984
The maintenance of adequate upright BP requires both a baroreceptor-mediated feedback loop and an effective circulating blood volume. Although functional disruptions of these mechanisms are reversible and common, several permanent and often progressive neurologic disorders exist that interfere with necessary reflexes and orthostatic BP control ...
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Droxidopa for neurogenic orthostatic hypotension

Expert Opinion on Orphan Drugs, 2015
Introduction: Neurogenic orthostatic hypotension is a disabling manifestation of autonomic failure seen in disorders such as multiple system atrophy, pure autonomic failure, Lewy body disease, Parkinson’s disease, autonomic neuropathies and dopamine β-hydroxylase deficiency.Areas covered: Droxidopa is an orally administered norepinephrine prodrug that ...
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[Medication for Neurogenic Orthostatic Hypotension].

Brain and nerve = Shinkei kenkyu no shinpo, 2023
Orthostatic hypotension is a phenomenon characterized by reduction in blood pressure secondary to the inability to adapt to changes in blood volume distribution (pooling of blood in the lower extremities) observed when standing from a seated or supine position. Orthostatic hypotension is classified into neurogenic and non-neurogenic types.
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