Results 191 to 200 of about 16,632 (221)
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Droxidopa for neurogenic orthostatic hypotension
Expert Opinion on Orphan Drugs, 2015Introduction: Neurogenic orthostatic hypotension is a disabling manifestation of autonomic failure seen in disorders such as multiple system atrophy, pure autonomic failure, Lewy body disease, Parkinson’s disease, autonomic neuropathies and dopamine β-hydroxylase deficiency.Areas covered: Droxidopa is an orally administered norepinephrine prodrug that ...
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Management of Supine Hypertension Complicating Neurogenic Orthostatic Hypotension
CNS Drugs, 2017Neurogenic orthostatic hypotension (NOH) can be present in a number of disorders, including synucleinopathies, autoimmune disorders, and various genetic disorders. All are characterized by defective norepinephrine release from sympathetic terminals upon standing, resulting in impaired vasoconstriction.
Jacquie, Baker, Kurt, Kimpinski
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Droxidopa approved for neurogenic orthostatic hypotension
American Journal of Health-System Pharmacy, 2014Droxidopa, a synthetic amino acid precursor of norepinephrine, has been approved as oral therapy for the treatment of neurogenic orthostatic hypotension, FDA and Chelsea Therapeutics announced on February 18.
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All orthostatic hypotension is neurogenic
Clinical Autonomic Research, 2023openaire +2 more sources
Efficacy of Midodrine for Neurogenic Orthostatic Hypotension
JAMA: The Journal of the American Medical Association, 1997To the Editor. —Orthostatic hypotension due to autonomic failure is an incapacitating condition for which treatment, despite various drug interventions (eg, yohimbine, metoclopramide, β-blockers, somatostatin analog) is not yet resolved. Therefore, the encouraging results of the study of Dr Low and colleagues 1 are potentially of great importance ...
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Mechanisms underlying unawareness of neurogenic orthostatic hypotension
Clinical Autonomic Research, 2020Philip W, Tipton, William P, Cheshire
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