Results 21 to 30 of about 16,906 (241)

Ampreloxetine Versus Droxidopa in Neurogenic Orthostatic Hypotension: A Comparative Review. [PDF]

Cureus, 2023
Neurogenic orthostatic hypotension (nOH) is a disabling problem of autonomic dysfunction in patients with Parkinson’s disease, which is associated with poor quality of life and higher mortality rates.
Hoxhaj P, Shah S, Muyolema Arce VE, Khan W, Sadeghzadegan A, Singh S, Collado GF, Goyal A, Khawaja I, Botlaguduru D, Razzaq W, Abdin ZU, Gupta I.   +12 more
europepmc   +2 more sources

Neurogenic orthostatic hypotension in Parkinson's disease: is there a role for locus coeruleus magnetic resonance imaging? [PDF]

J Neural Transm (Vienna), 2023
Locus coeruleus (LC) is the main noradrenergic nucleus of the brain, and degenerates early in Parkinson’s disease (PD). The objective of this study is to test whether degeneration of the LC is associated with orthostatic hypotension (OH) in PD.
Palermo G, Galgani A, Bellini G, Lombardo F, Martini N, Morganti R, Paoli D, De Cori S, Frijia F, Siciliano G, Ceravolo R, Giorgi FS.   +11 more
europepmc   +2 more sources

Effects of Daily Lifestyle Habits on Non-Neurogenic Orthostatic Hypotension in Older Adults in South Korea: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Background: Orthostatic hypotension (OH) is a chronic, debilitating condition common in older adults. This study examined the effects of daily lifestyle habits on non-neurogenic OH in older adults in South Korea.
Kim N, Oh HK.
europepmc   +2 more sources

Effects of Atomoxetine for the Treatment of Neurogenic Orthostatic Hypotension in Patients With Alpha-synucleinopathies: A Systematic Review of Randomized Controlled Trials and a Focus-Group Discussion. [PDF]

J Clin Neurol, 2023
Background and Purpose Neurogenic orthostatic hypotension (nOH) is one of the most important nonmotor symptoms in patients with α-synucleinopathies. Atomoxetine is a selective norepinephrine transporter blocker that is a treatment option for nOH.
Jung YJ, Kim A, Okamoto LE, Hong WH.
europepmc   +2 more sources

Cerebral perfusion in neurogenic orthostatic hypotension [PDF]

The Lancet Neurology, 2008
Contains fulltext : 69875.pdf (Author’s version postprint ) (Open Access)
Jurgen A.H.R. Claassen
openalex   +4 more sources

Cerebral Blood Flow Dynamics in Neurogenic Orthostatic Hypotension: A Systematic Review and Meta-Analysis. [PDF]

Hypertension
BACKGROUND: Neurogenic orthostatic hypotension (nOH) causes pathological falls in standing blood pressure that may or may not be symptomatic. nOH also raises the risk of poor neurological outcomes irrespective of symptom presence, possibly reflecting ...
Baker JR, Beach PA, Ranada SI, Patel A, Gewandter J, Tan CO, Freeman R, Raj SR.   +7 more
europepmc   +2 more sources

Epidural Spinal Cord Stimulation to Treat Neurogenic Orthostatic Hypotension in Multiple System Atrophy: A New Hope? [PDF]

Mov Disord Clin Pract, 2022
Multiple system atrophy (MSA) is a neurodegenerative movement disorder clinically characterized by a combination of different degrees of parkinsonism, cerebellar ataxia, and autonomic dysfunction.
Millar Vernetti P.
europepmc   +2 more sources

Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management [PDF]

Journal of Neurology, 2012
Neurogenic orthostatic hypotension is a distinctive and treatable sign of cardiovascular autonomic dysfunction. It is caused by failure of noradrenergic neurotransmission that is associated with a range of primary or secondary autonomic disorders, including pure autonomic failure, Parkinson's disease with autonomic failure, multiple system atrophy as ...
Manuela Metzler, Susanne Duerr, Roberta Granata, Florian Krismer, David Robertson, Gregor K. Wenning   +5 more
openalex   +4 more sources

Reduction in Pulse Pressure during Standing Can Distinguish Neurogenic Orthostatic Hypotension [PDF]

Diagnostics, 2021
Background: We investigated whether changes in the pulse pressure (PP) reduction ratio during the head-up tilt test (HUTT) can aid in distinguishing neurogenic orthostatic hypotension (OH) from non-neurogenic OH. Methods: We enrolled consecutive patients
Kyu-On Jung, Deok-Hyun Heo, Eek-Sung Lee, Tae-Kyeong Lee   +3 more
doaj   +2 more sources

Norepinephrine Reuptake Inhibition, an Emergent Treatment for Neurogenic Orthostatic Hypotension. [PDF]

Hypertension
The NET (norepinephrine transporter) is situated in the prejunctional plasma membrane of noradrenergic neurons. It is responsible for >90% of the norepinephrine uptake that is released in the autonomic neuroeffector junction.
Mwesigwa N, Shibao CA.
europepmc   +2 more sources