Differences in magnetic particle uptake by CNS neuroglial subclasses: implications for neural tissue engineering [PDF]
AIM: To analyze magnetic particle uptake and intracellular processing by the four main non-neuronal subclasses of the CNS: oligodendrocyte precursor cells; oligodendrocytes; astrocytes; and microglia.
Chari, DM+4 more
core +1 more source
Matrix Metalloproteinase-9 and Inflammation in Different Types of Multiple Sclerosis [PDF]
Different clinical courses of multiple sclerosis, heterogeneity of its clinical implications, different effect of immunomodulatory therapy for the same clinical forms implies various pathogenetic mechanisms of central nervous system damage at this ...
Chernenko, M. (Maksym)+4 more
core +2 more sources
Combining cellular and gene therapy approaches for treatment of intracranial tumors. [PDF]
New treatments are needed for brain metastasis, which is associated with high morbidity and mortality. Two novel cellular and gene therapy modalities were evaluated in xenograft models for human breast cancer.
Hickey, Michelle J+3 more
core +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Inflammation and oxidative stress are interlinked and interdependent processes involved in many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases, and cancer.
Roberto Iorio+2 more
doaj +1 more source
History of Neuroscience: Mesoglia and Microglia [PDF]
Microglia are mononuclear phagocytes that reside within the central nervous system (CNS). They differ from macroglia (astrocytes and oligodendrocytes) in terms of their origin, phenotype and functions, but more closely resemble tissue-resident ...
Rezaie, Payam
core
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Effects of Cabergoline and Levetiracetam on the Histological and Stereological Structure of the Cerebral Cortex, Hippocampus and Cerebellum of Rats With Pentylenetetrazol-Induced Seizure [PDF]
Background: Epilepcy is a chronic neurological disease, and due to its complex mechanism, the current therapeutic drugs for it are not effective enough. It may have a non-neurological origin such as astrocytes and microglia.
Mohammad Hossein Hajati Pishvari+2 more
doaj
Neuroimmune Regulation of Surgery-Associated Metastases
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression of ...
Michael R. Shurin+2 more
doaj +1 more source
Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae.
Alexander MP+29 more
core +1 more source