Results 41 to 50 of about 37,027 (220)

Integrating neuroscience and immunology core concepts to develop a neuroimmunology curriculum

Frontiers in Education
Training students in interdisciplinary thinking is critical for the future of scientific discovery and problem-solving more generally. Therefore, students must have early opportunities to grapple with knowns and unknowns at the frontiers of ...
Aparna P. Shah, Elizabeth C. Leininger, Sumali Pandey   +2 more
doaj   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes [PDF]

, 2016
Objective: To characterize the patterns of autoantibodies to glycolipid complexes in a large cohort of Guillain-Barré syndrome (GBS) and control samples collected in Bangladesh using a newly developed microarray technique.
Endtz, Hubert P., Halstead, Susan K., Islam, Mohammad B., Islam, Zhahirul, Jacobs, Bart C., Jahan, Israt, Kalna, Gabriela, Mohammad, Quazi D., Willison, Hugh J.   +8 more
core   +5 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

The future of neuroimmunology

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Neuroimmunology is one of the most potential fields of brain science, which challenges the neurologists. The development of antibody spectrum, the deepening research of mechanism and the precision of treatment make the future of this field full of ...
Sheng CHEN, Qin⁃ming ZHOU, You NI
doaj  

The IL‐27/IL‐27R axis is altered in CD4+ and CD8+ T lymphocytes from multiple sclerosis patients

Clinical & Translational Immunology, 2021
Objectives Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined.
Marie‐Laure Clénet, Cyril Laurent, Florent Lemaitre, Negar Farzam‐kia, Olivier Tastet, Odile Devergne, Boaz Lahav, Marc Girard, Pierre Duquette, Alexandre Prat, Catherine Larochelle, Nathalie Arbour   +11 more
doaj   +1 more source

Course of neuromyelitis optica during inadvertent pregnancy in a patient treated with rituximab [PDF]

, 2009
In neuromyelitis optica (NMO), the monoclonal B-cell antibody rituximab is a therapeutic option. Little is known about the course of NMO and the safety of rituximab during pregnancy.
Hohlfeld, R., Kümpfel, Tania, Pellkofer, H. L., Schulze, A., Suessmair, C.   +4 more
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 2013
Astrocytes play a vital role in neuronal protection, homeostasis, vascular interchange and the local immune response. Some viruses and parasites can cross the blood-brain barrier and infect glia.
Juan Camilo Vargas-Zambrano, Paola Lasso, Adriana Cuellar, Concepción Judith Puerta, John Mario González   +4 more
doaj   +1 more source

Distinct cytokine profiles across trajectories of self-perceived cognitive impairment among early-stage breast cancer survivors. [PDF]

, 2020
The aim of the current study is to identify distinct cytokine profiles in relation to self-perceived cognitive trajectories. In our study cohort (n = 128), early-stage breast cancer patients were categorized into no impairment reported, acute ...
Chan, Alexandre, Ho, Han Kiat, Toh, Yi Long, Wang, Claire   +3 more
core   +1 more source