Results 41 to 50 of about 24,021 (224)

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Juvenile myasthenia gravis: Comparison of pre and postpubertal cases

, 2014
12th International Congress of Neuroimmunology (ISNI) -- NOV 09-13, 2014 -- Mainz ...
Karasoy, Hatice, Ekmekci, Ozgul, Yuceyar, Ayse Nur   +2 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Neuroimmunology and synaptic function

, 2015
This Special Issue of Neuropharmacology is devoted to specific aspects of neuroimmunology and synaptic function. It contains 12 invited reviews from eminent scientists from all around the globe. These distinguished experts in the field of neuroimmunology
O\u27Connor, J. J., O'Connor, J. J.
core   +1 more source

Consensus recommendations of the Italian Association for Neuroimmunology for immunochemical cerebrospinal fluid examination

, 2005
In 2002-2003, the Italian Association for Neuroimmunology (AINI) ran a program for procedure and method standardization in neuroimmunology. The main purposes of the program were: a) to improve the overall quality of analytical performance and ...
Villa C., Meucci G., Ciranni A. M., Galli E., Gallo P., Zaffaroni M., Passerini G., Annunziata P., Bonetti B., Aguennouz M., Lugaresi A., Ciusani E., Avolio C., Castellazzi M., Andreoni L., Morucci A., Cocco E., Carpo M., Marrosu M., Sala A., Di Viesti P., Desina G., Allaria S., Cuccia S., Maimone D., Ribizzi G., Bedin R., Lolli F., Alberti D., Falcone M., Paolino E., Salmaggi A., Nobile-Orazio E., Sotgiu S., Bertolotto A., Deiana G., Siciliano G., Leante R., Bernardi G., Franciotta D., Merelli E., Pantalone A., Costa G., Zardini E., Apollo F., Capello E., Trojano M., Murru M. R., Panarese C., Chicchi A., Giunti D., Vita G., Simone P., Bacci A.   +53 more
core   +3 more sources

The future of neuroimmunology

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Neuroimmunology is one of the most potential fields of brain science, which challenges the neurologists. The development of antibody spectrum, the deepening research of mechanism and the precision of treatment make the future of this field full of ...
Sheng CHEN, Qin⁃ming ZHOU, You NI
doaj  

The IL‐27/IL‐27R axis is altered in CD4+ and CD8+ T lymphocytes from multiple sclerosis patients

Clinical & Translational Immunology, 2021
Objectives Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined.
Marie‐Laure Clénet, Cyril Laurent, Florent Lemaitre, Negar Farzam‐kia, Olivier Tastet, Odile Devergne, Boaz Lahav, Marc Girard, Pierre Duquette, Alexandre Prat, Catherine Larochelle, Nathalie Arbour   +11 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 2013
Astrocytes play a vital role in neuronal protection, homeostasis, vascular interchange and the local immune response. Some viruses and parasites can cross the blood-brain barrier and infect glia.
Juan Camilo Vargas-Zambrano, Paola Lasso, Adriana Cuellar, Concepción Judith Puerta, John Mario González   +4 more
doaj   +1 more source