Results 111 to 120 of about 9,739 (239)

Integrative Machine Learning Framework for Epigenetic Biomarker Discovery and Disease Severity Prediction in Childhood Atopic Dermatitis

open access: yesBig Data and Cognitive Computing
Atopic dermatitis (AD) is a chronic inflammatory skin disorder that is significantly contributed to by epigenetics. We developed a machine learning-based framework to identify DNA methylation biomarkers associated with AD classification and severity ...
Ding-Wei Chen, Yun-Nan Chang
doaj   +1 more source

Fifth International Congress of International Society for Neuroimmunomodulation, Le Corum, Montpellier, France, September 9–11, 2002 [PDF]

open access: bronze, 2002
W Billewicz   +63 more
openalex   +1 more source

Brain fog in Parkinson’s disease: unraveling mechanisms and measuring impact

open access: yesFrontiers in Neurology
Inconsistent colloquial and professional uses of the term “brain fog” have undermined the potential for empirical study of this symptom complex, and there is no consensus about how to diagnose or treat it. Yet brain fog is frequently reported by patients
Timothy R. Elliott   +3 more
doaj   +1 more source

Physiological and pathophysiological role of somatostatin receptors in the human thymus [PDF]

open access: yes, 2000
This is a review summarizing the physiological and pathophysiological role of somatostatin receptors in the human ...
Colao, A. (Annamaria)   +5 more
core   +1 more source

Fever induction pathways: evidence from responses to systemic or local cytokine formation

open access: yesBrazilian Journal of Medical and Biological Research, 2001
The immune and central nervous systems are functionally connected and interacting. The concept that the immune signaling to the brain which induces fever during infection and inflammation is mediated by circulating cytokines has been traditionally ...
Roth J., de Souza G.E.P.
doaj  

Immunosuppressive effect and global dysregulation of blood transcriptome in response to psychosocial stress in vervet monkeys (Chlorocebus sabaeus). [PDF]

open access: yes, 2020
Psychosocial stressors - life events that challenge social support and relationships - represent powerful risk factors for human disease; included amongst these events are relocation, isolation and displacement.
Benjamin, Cassandra   +8 more
core  

Interferon-α2b Modulates AMPA and Kainate Receptors and Alters Cross Talk of AMPA and NMDA Receptors in the Frog Vestibular Epithelium

open access: yesFrontiers in Bioscience-Landmark
Background: Interferons (IFNs) are ototoxic drugs leading to vestibular and auditory disorders. This study investigated the effect of pro-inflammatory cytokine IFN-α2b on the afferent glutamatergic synaptic transmission of the ...
Irina V. Ryzhova   +3 more
doaj   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

open access: yes, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien   +4 more
core   +1 more source

Thyroid Autoimmunity as a Window to Autoimmunity: An Explanation for Sex Differences in the Prevalence of Thyroid Autoimmunity [PDF]

open access: yes, 2015
Autoimmune thyroid diseases (AITDs), predominately Graves׳ disease and Hashimoto׳s thyroiditis, comprise the most common autoimmune diseases in humans.
Merrill, Stephen, Mu, Ying
core   +1 more source

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