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Cannabinoids and neuroinflammation [PDF]
British Journal of Pharmacology, 2004 Growing evidence suggests that a major physiological function of the cannabinoid signaling system is to modulate neuroinflammation. This review discusses the anti‐inflammatory properties of cannabinoid compounds at molecular, cellular and whole animal levels, first by examining the evidence for anti‐inflammatory effects of cannabinoids obtained using ...
Lisa Walter, Nephi Stella
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Innate immunity and neuroinflammation [PDF]
Mediators of Inflammation, 2013 Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
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RelB and Neuroinflammation [PDF]
Cells, 2021 Neuroinflammation within the central nervous system involves multiple cell types that coordinate their responses by secreting and responding to a plethora of inflammatory mediators. These factors activate multiple signaling cascades to orchestrate initial inflammatory response and subsequent resolution.
Tomasz Kordula +2 more
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Neuroinflammation and neuropathology
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2021 This review addresses the current understanding of the role of autoimmune neuroinflammation in the pathogenesis of vascular, neurodegenerative, and other diseases of the nervous system. The mechanisms of responses of resident CNS cells (glial cells, astrocytes) and peripheral immune system cells are presented.
Esin R.G. +3 more
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Frontiers in Molecular Neuroscience, 2023 Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disease caused by CAG repeats in exon 1 of the HTT gene. A hallmark of HD along with other psychiatric and neurodegenerative diseases is alteration in the neuronal circuitry ...
Julien Gasser +7 more
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Frontiers in Immunology, 2023 NOD-Like Receptor Family Pyrin Domain Containing 3 (NLRP3) inflammasome modulation has emerged as a potential therapeutic approach targeting inflammation amplified by pyroptotic innate immune cell death.
Marie-Laure Clénet +7 more
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PPARs in Neuroinflammation [PDF]
PPAR Research, 2008 Welcome to this special issue of PPAR Research dedicated to “PPARs in Neuroinflammation.” The central nervous system (CNS) was once thought to be an immune-privileged site void of significant inflammation. However, it is now clear that activated peripheral immune cells are capable or entering and functioning within the CNS. In addition, resident immune
Michael K. Racke, Paul D. Drew
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Mediators of Neuroinflammation [PDF]
Mediators of Inflammation, 2013 The understanding that neuroinflammation contributes to neurodegeneration and neuropathic pain is an emerging feature in a growing number of nervous system pathologies. Despite the immunoprivileged status of the central nervous system (CNS), its resident macrophages, microglia, with the help of other immune cells recruited from the blood, can mount ...
Geeta Ramesh +4 more
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Brain, Behavior, & Immunity - Health, 2020 Early life adversities during childhood (such as maltreatment, abuse, neglect, or parental deprivation) may increase the vulnerability to cognitive disturbances and emotional disorders in both, adolescence and adulthood.
S. Bachiller +4 more
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Scientific Reports, 2021 Microglial cells are affected in Alzheimer’s disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory loss, depression is common in patients with AD.
Martina Svensson +6 more
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