Results 1 to 10 of about 308,337 (381)
Neuroinflammation in Alzheimer's disease
Lancet Neurology, 2015 Michael T. Heneka +35 more
openalex +3 more sources
Frontiers in Molecular Neuroscience, 2023 Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disease caused by CAG repeats in exon 1 of the HTT gene. A hallmark of HD along with other psychiatric and neurodegenerative diseases is alteration in the neuronal circuitry ...
Julien Gasser +7 more
doaj +1 more source
Neuroinflammation and neuropathology
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2021 This review addresses the current understanding of the role of autoimmune neuroinflammation in the pathogenesis of vascular, neurodegenerative, and other diseases of the nervous system. The mechanisms of responses of resident CNS cells (glial cells, astrocytes) and peripheral immune system cells are presented.
Esin R.G. +3 more
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Role of neuroinflammation in neurodegeneration development
Signal Transduction and Targeted Therapy, 2023 Studies in neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and Amyotrophic lateral sclerosis, Huntington’s disease, and so on, have suggested that inflammation is not only a result of neurodegeneration but also a crucial ...
Weifeng Zhang +3 more
semanticscholar +1 more source
Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression
Translational Psychiatry, 2023 Mood disorders are associated with elevated inflammation, and the reduction of symptoms after multiple treatments is often accompanied by pro-inflammation restoration.
Bingqi Guo +5 more
semanticscholar +1 more source
Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation
Journal of Neuroinflammation, 2023 Alzheimer’s Disease (AD) contributes to most cases of dementia. Its prominent neuropathological features are the extracellular neuritic plaques and intercellular neurofibrillary tangles composed of aggregated β-amyloid (Aβ) and hyperphosphorylated tau ...
Yijun Chen, Yang Yu
semanticscholar +1 more source
RelB and Neuroinflammation [PDF]
Cells, 2021 Neuroinflammation within the central nervous system involves multiple cell types that coordinate their responses by secreting and responding to a plethora of inflammatory mediators. These factors activate multiple signaling cascades to orchestrate initial inflammatory response and subsequent resolution.
Karli Mockenhaupt +2 more
openaire +3 more sources
Frontiers in Immunology, 2023 NOD-Like Receptor Family Pyrin Domain Containing 3 (NLRP3) inflammasome modulation has emerged as a potential therapeutic approach targeting inflammation amplified by pyroptotic innate immune cell death.
Marie-Laure Clénet +7 more
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Frontiers in Psychiatry, 2023 In a subset of patients, chronic exposure to stress is an etiological risk factor for neuroinflammation and depression. Neuroinflammation affects up to 27% of patients with MDD and is associated with a more severe, chronic, and treatment-resistant ...
Sameer Hassamal
semanticscholar +1 more source
Microglia Mediated Neuroinflammation in Parkinson’s Disease
Cells, 2023 Parkinson’s Disease (PD) is the second most common neurodegenerative disorder seen, especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance and coordination are among the hallmarks, and dopaminergic neuronal loss in ...
Sevim Isik +4 more
semanticscholar +1 more source