Results 21 to 30 of about 211,053 (311)
Neuroinflammation in Synucleinopathies
Brain Pathology, 2016 AbstractThe causes of most neurodegenerative diseases are attributed to multiple genetic and environmental factors interacting with one another. Above all, inflammation in the nervous system has been implicated in many neurodegenerative diseases. Still, the roles of neuroinflammation in disease mechanisms and the triggers of inflammatory responses in ...
Somin, Lim +3 more
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Journal of Neuroinflammation, 2018 Background Small-diameter, myelinated axons are selectively susceptible to dysfunction in several inflammatory PNS and CNS diseases, resulting in pain and degeneration, but the mechanism is not known.
Marija Sajic +5 more
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Cells, 2021 In species that regenerate the injured spinal cord, the ependymal region is a source of new cells and a prominent coordinator of regeneration. In mammals, cells at the ependymal region proliferate in normal conditions and react after injury, but in ...
Alejandro Torrillas de la Cal +7 more
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Role of neuroinflammation in the pathophysiology of traumatic brain injury
, 2022 [[abstract]]Traumatic brain injury (TBI) is a serious public health problem causing morbidity and mortality worldwide yearly. Neuroinflammation is a hallmark symptom following TBI to induce delayed secondary injury. The excessive activation of microglia,
Wu, CYC;Lee, RHC;Lee, MHH;do Couto e Silva, A;Hsieh, TH;Possoit, H;Brackett, AL;Lin, HW
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Imaging of neuroinflammation [PDF]
European Journal of Nuclear Medicine and Molecular Imaging, 2011 For those of us interested in molecular imaging of the majorneurodegenerative disorders, the last decade has witnessed amarked advancement. From basic research to clinical studies,the field has evolved using multidisciplinary techniques andskills, leading to results of significant clinical interest.Reasoning on the role of inflammation in ...
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Mediators of Neuroinflammation [PDF]
Mediators of Inflammation, 2013 The understanding that neuroinflammation contributes to neurodegeneration and neuropathic pain is an emerging feature in a growing number of nervous system pathologies. Despite the immunoprivileged status of the central nervous system (CNS), its resident macrophages, microglia, with the help of other immune cells recruited from the blood, can mount ...
Geeta Ramesh +4 more
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Acute systemic LPS-exposure impairs perivascular CSF distribution in mice
Journal of Neuroinflammation, 2021 Background The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial ...
Oscar Manouchehrian +4 more
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Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors? [PDF]
, 2012 Acknowledgements We thank Stefanie Hofer-Reyes for proofreading the manuscriptPeer ...
Gertsch, Jürg +5 more
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Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology
Journal of Neuroinflammation, 2023 Background Increasing evidence supports a key role for peripheral immune processes in the pathophysiology of Alzheimer’s disease (AD), highlighting an intricate interplay between brain resident glial cells and both innate and adaptive peripheral immune ...
Grégoire Stym-Popper +8 more
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Neuroinflammation in Friedreich’s Ataxia
International Journal of Molecular Sciences, 2022 Friedreich’s ataxia (FRDA) is a rare genetic disorder caused by mutations in the gene frataxin, encoding for a mitochondrial protein involved in iron handling and in the biogenesis of iron−sulphur clusters, and leading to progressive nervous system damage.
Apolloni, Savina +2 more
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