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Journal of Neuroinflammation, 2020 An amendment to this paper has been published and can be accessed via the original article.
Ferdinand Althammer +7 more
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Imaging of neuroinflammation [PDF]
European Journal of Nuclear Medicine and Molecular Imaging, 2011 For those of us interested in molecular imaging of the majorneurodegenerative disorders, the last decade has witnessed amarked advancement. From basic research to clinical studies,the field has evolved using multidisciplinary techniques andskills, leading to results of significant clinical interest.Reasoning on the role of inflammation in ...
openaire +3 more sources
Curcumin Prevents Acute Neuroinflammation and Long-Term Memory Impairment Induced by Systemic Lipopolysaccharide in Mice [PDF]
, 2018 Systemic lipopolysaccharide (LPS) induces an acute inflammatory response in the central nervous system (CNS) (\u201cneuroinflammation\u201d) characterized by altered functions of microglial cells, the major resident immune cells of the CNS, and an ...
Confortin, Francesca +7 more
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Cells, 2021 In species that regenerate the injured spinal cord, the ependymal region is a source of new cells and a prominent coordinator of regeneration. In mammals, cells at the ependymal region proliferate in normal conditions and react after injury, but in ...
Alejandro Torrillas de la Cal +7 more
doaj +1 more source
Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease. [PDF]
, 2015 BackgroundParkinson's disease (PD) is one of the most common causes of dementia and motor deficits in the elderly. PD is characterized by the abnormal accumulation of the synaptic protein alpha-synuclein (α-syn) and degeneration of dopaminergic neurons ...
Anderson, Scott +4 more
core +2 more sources
Journal of Neuroinflammation, 2018 Background Small-diameter, myelinated axons are selectively susceptible to dysfunction in several inflammatory PNS and CNS diseases, resulting in pain and degeneration, but the mechanism is not known.
Marija Sajic +5 more
doaj +1 more source
Acute systemic LPS-exposure impairs perivascular CSF distribution in mice
Journal of Neuroinflammation, 2021 Background The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial ...
Oscar Manouchehrian +4 more
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PPARs in Neuroinflammation [PDF]
PPAR Research, 2008 Welcome to this special issue of PPAR Research dedicated to “PPARs in Neuroinflammation.” The central nervous system (CNS) was once thought to be an immune-privileged site void of significant inflammation. However, it is now clear that activated peripheral immune cells are capable or entering and functioning within the CNS. In addition, resident immune
Paul D. Drew, Michael K. Racke
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Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology
Journal of Neuroinflammation, 2023 Background Increasing evidence supports a key role for peripheral immune processes in the pathophysiology of Alzheimer’s disease (AD), highlighting an intricate interplay between brain resident glial cells and both innate and adaptive peripheral immune ...
Grégoire Stym-Popper +8 more
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Neuroinflammation in Friedreich’s Ataxia
International Journal of Molecular Sciences, 2022 Friedreich’s ataxia (FRDA) is a rare genetic disorder caused by mutations in the gene frataxin, encoding for a mitochondrial protein involved in iron handling and in the biogenesis of iron−sulphur clusters, and leading to progressive nervous system damage.
Apolloni, Savina +2 more
openaire +3 more sources