Results 11 to 20 of about 264,543 (300)
S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]
, 2015 Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena +6 more
core +5 more sources
Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
Frontiers in Cellular Neuroscience, 2018 Microglia represent a specialized population of macrophages-like cells in the central nervous system (CNS) considered immune sentinels that are capable of orchestrating a potent inflammatory response. Microglia are also involved in synaptic organization,
Sara Bachiller +6 more
doaj +1 more source
Cannabinoids and neuroinflammation [PDF]
British Journal of Pharmacology, 2004 Growing evidence suggests that a major physiological function of the cannabinoid signaling system is to modulate neuroinflammation. This review discusses the anti‐inflammatory properties of cannabinoid compounds at molecular, cellular and whole animal levels, first by examining the evidence for anti‐inflammatory effects of cannabinoids obtained using ...
Lisa, Walter, Nephi, Stella
openaire +2 more sources
An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]
, 2018 Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura +3 more
core +2 more sources
Journal of Neuroinflammation, 2020 Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and
Ferdinand Althammer +6 more
doaj +1 more source
Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation
Journal of Neuroinflammation, 2021 Background Aging and age-related diseases are strong risk factors for the development of neurodegenerative diseases. Neuroinflammation (NIF), as the brain’s immune response, plays an important role in aged associated degeneration of central nervous ...
Andrés Fernández +9 more
doaj +1 more source
Cells, 2022 The risk of complications following surgical procedures is significantly increased in patients with SARS-CoV-2 infection. However, the mechanisms underlying these correlations are not fully known.
Mario Martínez-Torija +13 more
doaj +1 more source
Neuroinflammation in Synucleinopathies
Brain Pathology, 2016 AbstractThe causes of most neurodegenerative diseases are attributed to multiple genetic and environmental factors interacting with one another. Above all, inflammation in the nervous system has been implicated in many neurodegenerative diseases. Still, the roles of neuroinflammation in disease mechanisms and the triggers of inflammatory responses in ...
Somin, Lim +3 more
openaire +3 more sources
Mediators of Neuroinflammation [PDF]
Mediators of Inflammation, 2013 The understanding that neuroinflammation contributes to neurodegeneration and neuropathic pain is an emerging feature in a growing number of nervous system pathologies. Despite the immunoprivileged status of the central nervous system (CNS), its resident macrophages, microglia, with the help of other immune cells recruited from the blood, can mount ...
Geeta Ramesh +4 more
openaire +3 more sources
Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage [PDF]
, 2015 Background Traumatic brain injury can trigger chronic neuroinflammation, which may predispose to neurodegeneration. Animal models and human pathological studies demonstrate persistent inflammation in the thalamus associated with axonal injury, but this ...
Brooks, DJ +5 more
core +1 more source