Results 11 to 20 of about 258,336 (300)
S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]
, 2015 Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena +6 more
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Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
Frontiers in Cellular Neuroscience, 2018 Microglia represent a specialized population of macrophages-like cells in the central nervous system (CNS) considered immune sentinels that are capable of orchestrating a potent inflammatory response. Microglia are also involved in synaptic organization,
Sara Bachiller +6 more
doaj +1 more source
Curcumin Prevents Acute Neuroinflammation and Long-Term Memory Impairment Induced by Systemic Lipopolysaccharide in Mice [PDF]
, 2018 Systemic lipopolysaccharide (LPS) induces an acute inflammatory response in the central nervous system (CNS) (\u201cneuroinflammation\u201d) characterized by altered functions of microglial cells, the major resident immune cells of the CNS, and an ...
Confortin, Francesca +7 more
core +2 more sources
Journal of Neuroinflammation, 2020 Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and
Ferdinand Althammer +6 more
doaj +1 more source
Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation
Journal of Neuroinflammation, 2021 Background Aging and age-related diseases are strong risk factors for the development of neurodegenerative diseases. Neuroinflammation (NIF), as the brain’s immune response, plays an important role in aged associated degeneration of central nervous ...
Andrés Fernández +9 more
doaj +1 more source
An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]
, 2018 Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura +3 more
core +2 more sources
Cells, 2022 The risk of complications following surgical procedures is significantly increased in patients with SARS-CoV-2 infection. However, the mechanisms underlying these correlations are not fully known.
Mario Martínez-Torija +13 more
doaj +1 more source
Cells, 2021 In species that regenerate the injured spinal cord, the ependymal region is a source of new cells and a prominent coordinator of regeneration. In mammals, cells at the ependymal region proliferate in normal conditions and react after injury, but in ...
Alejandro Torrillas de la Cal +7 more
doaj +1 more source
Targeting neuroinflammation in Alzheimer’s disease [PDF]
, 2016 Almost 47 million people suffer from dementia worldwide, with an estimated new case diagnosed every 3.2 seconds. Alzheimer’s disease (AD) accounts for approximately 60%–80% of all dementia cases. Given this evidence, it is clear dementia represents one
Bronzuoli, MARIA ROSANNA +3 more
core +1 more source
Journal of Neuroinflammation, 2020 An amendment to this paper has been published and can be accessed via the original article.
Ferdinand Althammer +7 more
doaj +1 more source