Results 11 to 20 of about 135,205 (333)
Cannabinoids and neuroinflammation [PDF]
British Journal of Pharmacology, 2004 Growing evidence suggests that a major physiological function of the cannabinoid signaling system is to modulate neuroinflammation. This review discusses the anti‐inflammatory properties of cannabinoid compounds at molecular, cellular and whole animal levels, first by examining the evidence for anti‐inflammatory effects of cannabinoids obtained using ...
Lisa Walter, Nephi Stella
openalex +4 more sources
RelB and Neuroinflammation [PDF]
Cells, 2021 Neuroinflammation within the central nervous system involves multiple cell types that coordinate their responses by secreting and responding to a plethora of inflammatory mediators. These factors activate multiple signaling cascades to orchestrate initial inflammatory response and subsequent resolution.
Tomasz Kordula +2 more
openaire +4 more sources
Molecular pathogenesis of neuroinflammation [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2003 The past few years have seen significant progress towards understanding the mechanisms of immune surveillance and inflammation in the nervous system. In this review, the milestones of scientific discovery in this field are discussed, and the strengths and limitations of the different ways of examining the molecular pathogenesis of neuro-inflammation ...
Monika Bradl, Reinhard Hohlfeld
openalex +5 more sources
Neuroinflammation and neuropathology
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2021 This review addresses the current understanding of the role of autoimmune neuroinflammation in the pathogenesis of vascular, neurodegenerative, and other diseases of the nervous system. The mechanisms of responses of resident CNS cells (glial cells, astrocytes) and peripheral immune system cells are presented.
Esin R.G. +3 more
openaire +4 more sources
COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022 Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley +1 more source
Mediators of Neuroinflammation [PDF]
Mediators of Inflammation, 2013 The understanding that neuroinflammation contributes to neurodegeneration and neuropathic pain is an emerging feature in a growing number of nervous system pathologies. Despite the immunoprivileged status of the central nervous system (CNS), its resident macrophages, microglia, with the help of other immune cells recruited from the blood, can mount ...
Geeta Ramesh +4 more
openaire +3 more sources
PPARs in Neuroinflammation [PDF]
PPAR Research, 2008 Welcome to this special issue of PPAR Research dedicated to “PPARs in Neuroinflammation.” The central nervous system (CNS) was once thought to be an immune-privileged site void of significant inflammation. However, it is now clear that activated peripheral immune cells are capable or entering and functioning within the CNS. In addition, resident immune
Michael K. Racke, Paul D. Drew
openaire +3 more sources
Extracellular Vesicles in Neuroinflammation [PDF]
Frontiers in Cell and Developmental Biology, 2021 Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that play a pivotal role in cell–cell communication, not only participating in many physiological processes, but also contributing to the pathogenesis of several diseases.
Marostica G. +4 more
openaire +3 more sources
Neuroinflammation in Schizophrenia
Jurnal Psikiatri Surabaya, 2021 Schizophrenia is a chronic debilitating mental illness. In many aspects, the neuropathology of schizophrenia is closely associated with neuroinflammation, especially microglial activation. Microglial hyperactivity, which is characterized by the predominant release of proinflammatory cytokines serves as the basis of the neuroinflammation hypothesis in ...
Muhammad Nazmuddin +3 more
openaire +4 more sources
RIPped for neuroinflammation [PDF]
Cell Research, 2017 Activation of the receptor interacting serine/threonine kinase (RIPK) 3 mediates an inflammatory type of cell death called necroptosis; in addition, RIPK3 has necroptosis-independent roles in inflammation, although these are not well defined. In a recent study published in Cell, Daniels and colleagues demonstrate that RIPK3 controls West Nile virus ...
Bart Tummers, Douglas R. Green
openaire +3 more sources