Results 21 to 30 of about 308,337 (381)
PPARs in Neuroinflammation [PDF]
PPAR Research, 2008 Welcome to this special issue of PPAR Research dedicated to “PPARs in Neuroinflammation.” The central nervous system (CNS) was once thought to be an immune-privileged site void of significant inflammation. However, it is now clear that activated peripheral immune cells are capable or entering and functioning within the CNS. In addition, resident immune
Paul D. Drew, Michael K. Racke
openaire +3 more sources
BMC Medicine, 2023 Background Perioperative neurocognitive disorders (PND) with a high incidence frequently occur in elderly surgical patients closely associated with prolonged anesthesia-induced neurotoxicity.
Feng Xu +8 more
semanticscholar +1 more source
Senescent accelerated prone 8 (SAMP8) mice as a model of age dependent neuroinflammation
Journal of Neuroinflammation, 2021 Background Aging and age-related diseases are strong risk factors for the development of neurodegenerative diseases. Neuroinflammation (NIF), as the brain’s immune response, plays an important role in aged associated degeneration of central nervous ...
Andrés Fernández +9 more
doaj +1 more source
An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases
International Journal of Molecular Sciences, 2022 Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen ...
D. Teleanu +8 more
semanticscholar +1 more source
Striatal neuroinflammation promotes parkinsonism in rats [PDF]
, 2008 The specific role of neuroinflammation in the pathogenesis of Parkinson's disease remains to be fully elucidated. By infusing lipopolysaccharide (LPS) into the striatum, we investigated the effect of neuroinflammation on the dopamine nigrostriatal ...
Don Gash +9 more
core +6 more sources
Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
Frontiers in Cellular Neuroscience, 2018 Microglia represent a specialized population of macrophages-like cells in the central nervous system (CNS) considered immune sentinels that are capable of orchestrating a potent inflammatory response. Microglia are also involved in synaptic organization,
Sara Bachiller +6 more
doaj +1 more source
Journal of Neuroinflammation, 2020 Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and
Ferdinand Althammer +6 more
doaj +1 more source
Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities.
Stroke, 2022 Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central nervous system. Structurally comprising the BBB, brain endothelial cells interact with pericytes, astrocytes, neurons, microglia, and perivascular macrophages ...
E. Candelario-Jalil +2 more
semanticscholar +1 more source
S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]
, 2015 Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena +6 more
core +5 more sources
Cells, 2022 The risk of complications following surgical procedures is significantly increased in patients with SARS-CoV-2 infection. However, the mechanisms underlying these correlations are not fully known.
Mario Martínez-Torija +13 more
doaj +1 more source