Results 161 to 170 of about 92,938,436 (228)

Anti-Inflammatory Evaluation of Pyrazino[2,1-<i>b</i>]quinazoline-3,6-dione Derivatives Inspired by Fiscalin B. [PDF]

Pharmaceuticals (Basel)
Martins MS, Pinto MMM, Almeida IF, Cruz MT, Sousa E.   +4 more
europepmc   +1 more source

Response to: Letter to the Editor Regarding: Safety of Fezolinetant for Treatment of Moderate-to-Severe Vasomotor Symptoms Due to Menopause: Pooled Analysis of Three Randomized Phase 3 Studies. [PDF]

Adv Ther
Kagan R, Cano A, Nappi RE, English ML, Mancuso S, Wu X, Ottery FD.   +6 more
europepmc   +1 more source

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Neurokinin A. A pharmacological study

Pharmacological Research, 1990
Discovered in 1983, the decapeptide neurokinin A has been shown to occur in several peripheral organs and to exert a variety of biological effects. In this article, we review the most sensitive and selective in vivo and in vitro tests which have been used in various laboratories to evaluate naturally occurring or synthetic neurokinin A. A comparison of
N Rouissi, S Dion, G Drapeau
exaly   +3 more sources

Effect of kassinin, neurokinin A and neurokinin B on drinking behaviour in the pigeon

Regulatory Peptides, 1987
Intracerebroventricular (i.c.v.) injection of kassinin produced a prompt and copious drinking response at doses of 10-1000 ng/pigeon, in the absence of other behavioural alterations or of changes in core temperature. Neurokinin A and B evoked drinking, but they were respectively 10 and 100 times less potent than kassinin.
MASSI, Maurizio, PERFUMI, Marina Cecilia, POLIDORI, Carlo, de Caro G.   +3 more
core   +5 more sources

Neurokinin receptor antagonists

Expert Opinion on Investigational Drugs, 2000
Studies on tachykinin peptides and the corresponding neurokinin receptors (NKr) have increased dramatically recently due to the discovery of selective, orally-active, metabolically stable and sometimes CNS penetrating NKr antagonists. After demonstrating the potential use for NKr antagonists in animal models, some compounds have recently progressed ...
Norton Peet
exaly   +3 more sources

Neurokinin A and neurokinin B in the human retina

Peptides, 2006
Very recently, the authors found levels of neurokinin (NK) A-like immunoreactivities in the human retina which were more than five times higher than those of substance P (SP). The present study aimed to find out how many of these immunoreactivities can be attributed to NKA and NKB and then the exact distribution pattern of both NKA and NKB was ...
Eduard, Schmid, Johannes, Leierer, Gerhard, Kieselbach, Barbara, Teuchner, Martina, Kralinger, Reiner, Fischer-Colbrie, James E, Krause, Quynh Anh, Nguyen, Gertrud, Haas, Katrin, Stemberger, Josef, Troger   +10 more
openaire   +2 more sources

Neurokinin A and B

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1991
The chemical features, pharmacological and biochemical characteristics of novel mammalian tachykinin peptides, neurokinin A and neurokinin B are described and are compared with those of substance P, a representative of tachykinin family.
openaire   +2 more sources

Neurokinin A as a Potent Bronchoconstrictor

American Review of Respiratory Disease, 1987
Abstract Neurokinin A (NKA) and B (NKB) were more potent bronchoconstrictive agents than substance P (SP) in guinea pig tracheal strips. The content of NKA in guinea pig lung homogenate was 2.26 α 1.09 pmol/g wet lung, which was approximately half that of SP (4.46 α 1.33 pmol/g wet lung); NKB was not detected in the guinea pig lung ...
Y, Uchida, A, Nomura, M, Ohtsuka, S, Hasegawa, K, Goto, S, Kimura, Y, Sugita, Y, Uchiyama   +7 more
openaire   +2 more sources