Perampanel Attenuates Cognitive and Behavioral Deficits and Modulates Hippocampal Tachykinin Expression in Experimental Temporal Lobe Epilepsy [PDF]
Current Issues in Molecular BiologyBackground: Epilepsy is one of the most prevalent neurological disorders, often presenting alongside many comorbidities. The present study aimed to evaluate the impact of the antiepileptic drug perampanel (PRM) on cognitive function, depressive-like ...
Michaela Shishmanova-Doseva +2 more
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Tachykinins, new players in the control of reproduction and food intake: A comparative review in mammals and teleosts [PDF]
Frontiers in Endocrinology, 2022 In vertebrates, the tachykinin system includes tachykinin genes, which encode one or two peptides each, and tachykinin receptors. The complexity of this system is reinforced by the massive conservation of gene duplicates after the whole-genome ...
Aurora Campo +4 more
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What Is the Correlation between Preeclampsia and Cancer? The Important Role of Tachykinins and Transition Metal Ions [PDF]
Pharmaceuticals, 2023 Metal ions are irreplaceable in many biological processes. They are components of numerous metalloproteins and serve as cofactors or structural elements for enzymes.
Klaudia Szczerba, Kamila Stokowa-Soltys
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Tachykinins and Tachykinin Receptors in Human Uterus [PDF]
British Journal of Pharmacology, 2003 Studies were undertaken to determine the nature of the receptors mediating contractile effects of tachykinins in the uteri of nonpregnant women, and to analyse the expression of preprotachykinins (PPT), tachykinin receptors and the cell‐surface peptidase, neprilysin (NEP), in the myometrium from pregnant and nonpregnant women.
Carlos Flores +2 more
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Neurokinin-2 receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor [PDF]
Cell & Bioscience, 2023 Background Tachykinins and their cognate receptors, neurokinin receptors (NKs) including NK1, NK2, and NK3 play vital roles in regulating various physiological processes including neurotransmission, nociception, inflammation, smooth muscle contractility,
Lan Phuong Nguyen +11 more
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Functional Characterization of Tachykinin in Regulating Feeding and Energy Metabolism in the Chinese Oak Silkworm, Antheraea pernyi [PDF]
InsectsTachykinins (TKs), a conserved family of neuropeptides, play critical roles in regulating multiple physiological processes such as feeding and energy metabolism in insects. This study identified the TK gene (ApTK) from the Chinese oak silkworm, Antheraea
Guobao Wang, Yunhan Zhang, Yong Wang
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The Role of the Arcuate Nucleus in Regulating Hunger and Satiety in Prader-Willi Syndrome [PDF]
Current Issues in Molecular BiologyPrader-Willi syndrome (PWS) is a rare genetic disorder. The main characteristics are muscular hypotonia, failure to thrive and feeding problems in infancy, which switch to hyperphagia in early childhood and continue into adulthood.
Charlotte Höybye, Maria Petersson
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TAC3/TACR3 System Function in the Catadromous Migration Teleost, Anguilla japonica
Frontiers in Endocrinology, 2022 Neurokinin B (NKB), a member of the tachykinin (TAC) family, plays important roles in mammalian neuropeptide secretion in related to reproduction. However, its potential role in spawning migration teleost is less clear. In the present study, Japanese eel
Chenpeng Zuo +5 more
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Molecular Segmentation of the Spinal Trigeminal Nucleus in the Adult Mouse Brain
Frontiers in Neuroanatomy, 2021 The trigeminal column is a hindbrain structure formed by second order sensory neurons that receive afferences from trigeminal primary (ganglionic) nerve fibers.
Isabel M. García-Guillén +4 more
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Overexpression of Substance P in pig airways increases MUC5AC through an NF‐kβ pathway
Physiological Reports, 2021 Substance P (SP) is a tachykinin that regulates airway mucous secretion in both health and disease. Our study aimed to determine whether overexpression of SP without pre‐existing inflammation was sufficient to induce changes in mucin secretion and ...
Mariana Sponchiado +6 more
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