Results 21 to 30 of about 153 (129)
Plasma substance P and soluble P-selectin as biomarkers of β-thalassemia induced hypercoagulability
Alexandria Journal of Medicine, 2014 Background: Hypercoagulability in thalassemia especially in thalassemia major has emerged as a complication of the disease. There is evidence of increased platelet aggregation and increased proportion of platelets expressing P-selectin in thalassemia.
Samia A. Ebeid +3 more
doaj +1 more source
Toxinology of Cephalopods: A Review Article
Iranian South Medical Journal, 2021 Most cephalopods are venomous organisms whose major venom constituents include protein toxins, small toxic molecules, enzymes, and amines. Neurotoxic cephalotoxins are protein toxins that were first isolated from this family. They are categorized into SE-
Hossien Mohebbi, Ammar Maryamabadi
doaj
Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic
Frontiers in Neuroscience, 2019 Tachykinins (TKs) are ancient neuropeptides present throughout the bilaterians and are, with some exceptions, characterized by a conserved FX1GX2Ramide carboxy terminus among protostomes and FXGLMamide in deuterostomes.
Dick R. Nässel +3 more
doaj +1 more source
Journal of Occupational Medicine and Toxicology, 2008 Background Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg David A +3 more
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Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-κB and p38 MAPK signaling pathways. [PDF]
PLoS ONE, 2012 The mammalian tachykinins, substance P (SP) and hemokinin-1 (HK-1), are widely distributed throughout the nervous system and/or peripheral organs, and function as neurotransmitters or chemical modulators by activating their cognate receptor NK(1).
Atsushi Sakai +3 more
doaj +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Brain neuropeptides in central ventilatory and cardiovascular regulation in trout.
Frontiers in Endocrinology, 2012 Many neuropeptides and their G-protein coupled receptors (GPCRs) are present within the brain area involved in ventilatory and cardiovascular regulation but only a few mammalian studies have focused on the integrative physiological actions of ...
Jean-Claude eLe Mével +3 more
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Scientific Reports, 2022 Tachykinins (TKs) are a group of conserved neuropeptides. In insects, tachykinin-related peptides (TRPs) are important modulators of several functions such as nociception and lipid metabolism.
Arkadiusz Urbański +8 more
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Neurobiology of Disease, 2020 Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as Parkinson's disease. It is challenging to map neuropeptide changes across and within brain regions
Heather Hulme +10 more
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