Results 1 to 10 of about 5,502 (182)

Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta. [PDF]

PLoS Biology
Neurons contribute to the complex interplay of signals that mediate heart development and homeostasis. Although a limited set of studies suggest that neuronal peptides impact vertebrate heart growth, the specific contributions of these peptides to ...
Hannah N Gruner, C J Pickett, Jasmine Yimeng Bao, Richard Garcia, Akiko Hozumi, Tal D Scully, Sydney Popsuj, Shaoyang Ning, Mavis Gao, Gia Bautista, Keren Maze, HaEun Karissa Lim, Tomohiro Osugi, Mae Collins-Doijode, Ofubofu Cairns, Gabriel Levis, Shu Yi Chen, TaiXi Gong, Honoo Satake, Allon Moshe Klein, Yasunori Sasakura, Bradley Davidson   +21 more
doaj   +2 more sources

Comparative transcriptomics of lateral hypothalamic cell types reveals conserved growth hormone-tachykinin dynamics in feeding [PDF]

Molecular Metabolism
Objectives: The lateral hypothalamus (LH) plays a central role in appetite control, however the functional and evolutionary conservation of its subcircuits remain unclear.
Vindhya Chaganty, Ruey-Kuang Cheng, Kimberle Shen, Na Zhang, Gaynah Javier Doblado, Sarah Ong, Sandra Tan, Valarie Yu Yan Tham, Jung-Hwa Choi, Marnie E. Halpern, Wei Leong Chew, Anand Kumar Andiappan, Sarah Xinwei Luo, Caroline Lei Wee   +13 more
doaj   +2 more sources

Mast Cells and Substance P: Neuroinflammatory Loops at the Molecular and Translational Clinical Levels [PDF]

Biomolecules
Mast cells, characterized by a broad repertoire of surface receptors, are increasingly recognized for activation pathways extending beyond the classical IgE/FcεRI axis, particularly in the context of neurogenic inflammation.
Ernesto Aitella, Marilena Bruno, Gianluca Azzellino, Massimo De Martinis, Lia Ginaldi, Ciro Romano   +5 more
doaj   +2 more sources

Tachykinins, new players in the control of reproduction and food intake: A comparative review in mammals and teleosts

Frontiers in Endocrinology, 2022
In vertebrates, the tachykinin system includes tachykinin genes, which encode one or two peptides each, and tachykinin receptors. The complexity of this system is reinforced by the massive conservation of gene duplicates after the whole-genome ...
Aurora Campo, Aurora Campo, Sylvie Dufour, Karine Rousseau, Karine Rousseau   +4 more
doaj   +1 more source

Neuromodulation of olfactory sensitivity in the peripheral olfactory organs of the American cockroach, Periplaneta americana. [PDF]

PLoS ONE, 2013
Olfactory sensitivity exhibits daily fluctuations. Several studies have suggested that the olfactory system in insects is modulated by both biogenic amines and neuropeptides. However, molecular and neural mechanisms underlying olfactory modulation in the
Je Won Jung, Jin-Hee Kim, Rita Pfeiffer, Young-Joon Ahn, Terry L Page, Hyung Wook Kwon   +5 more
doaj   +1 more source

A class of secreted mammalian peptides with potential to expand cell-cell communication

Nature Communications, 2023
Peptide hormones and neuropeptides are signaling molecules that control diverse aspects of mammalian homeostasis and physiology. Here we provide evidence for the endogenous presence of a sequence diverse class of blood-borne peptides that we call “capped
Amanda L. Wiggenhorn, Hind Z. Abuzaid, Laetitia Coassolo, Veronica L. Li, Julia T. Tanzo, Wei Wei, Xuchao Lyu, Katrin J. Svensson, Jonathan Z. Long   +8 more
doaj   +1 more source

Tachykinins stimulate a subset of mouse taste cells. [PDF]

PLoS ONE, 2012
The tachykinins substance P (SP) and neurokinin A (NKA) are present in nociceptive sensory fibers expressing transient receptor potential cation channel, subfamily V, member 1 (TRPV1).
Jeff Grant
doaj   +1 more source

Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus

Reproductive Biology and Endocrinology, 2009
Background In the mouse uterus, pregnancy is accompanied by changes in tachykinin and tachykinin receptor gene expression and in the uterotonic effects of endogenous tachykinins. In this study we have investigated whether changes in tachykinin expression
Patak Eva, Pennefather Jocelyn N, Pintado C Oscar, Pinto Francisco M, Candenas Luz   +4 more
doaj   +1 more source

What Is the Correlation between Preeclampsia and Cancer? The Important Role of Tachykinins and Transition Metal Ions

Pharmaceuticals, 2023
Metal ions are irreplaceable in many biological processes. They are components of numerous metalloproteins and serve as cofactors or structural elements for enzymes.
Klaudia Szczerba, Kamila Stokowa-Soltys
doaj   +1 more source

Suppressive Effects of Glycyrrhetinic Acid Derivatives on Tachykinin Receptor Activation and Hyperalgesia

Journal of Pharmacological Sciences, 2011
.: Glycyrrhetinic acid (GA), an aglycone of glycyrrhizin, isolated from the licorice root (Glycyrrhizia), and its semi-synthetic derivatives have a wide range of pharmacological effects. To investigate whether GA derivatives may be used as a new class of
Yuko Akasaka, Atsushi Sakai, Kumiko Takasu, Michiko Tsukahara, Akira Hatta, Hidenori Suzuki, Hideo Inoue   +6 more
doaj   +1 more source