Results 11 to 20 of about 5,502 (182)

Tachykinins and tachykinin receptors in human uterus [PDF]

open access: yesBritish Journal of Pharmacology, 2003
Studies were undertaken to determine the nature of the receptors mediating contractile effects of tachykinins in the uteri of nonpregnant women, and to analyse the expression of preprotachykinins (PPT), tachykinin receptors and the cell‐surface peptidase, neprilysin (NEP), in the myometrium from pregnant and nonpregnant women.
Eva, Patak   +9 more
openaire   +2 more sources

Expression and function of human hemokinin-1 in human and guinea pig airways

open access: yesRespiratory Research, 2010
Background Human hemokinin-1 (hHK-1) and endokinins are peptides of the tachykinin family encoded by the TAC4 gene. TAC4 and hHK-1 expression as well as effects of hHK-1 in the lung and airways remain however unknown and were explored in this study ...
Sage Edouard   +6 more
doaj   +1 more source

Characterisation, localisation and expression of porcine TACR1, TACR2 and TACR3 genes

open access: yesVeterinární Medicína, 2017
Substance P is involved in many physiological and pathophysiological processes. This functional diversity is mediated by three neurokinin receptor subtypes (NK1R, NK2R and NK3R) encoded by the TACR1, TACR2 and TACR3 genes, respectively.
A. Jakimiuk   +3 more
doaj   +1 more source

Tachykinin receptors antagonism for asthma: a systematic review

open access: yesBMC Pulmonary Medicine, 2011
Background Tachykinins substance P, neurokinin A and neurokinin B seem to account for asthma pathophysiology by mediating neurogenic inflammation and several aspects of lung mechanics.
Couto Nuno   +3 more
doaj   +1 more source

Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

open access: yesERJ Open Research, 2021
Cough is induced by inhaled prostacyclin analogues including treprostinil (TRE), and, at higher doses, treprostinil palmitil (TP), a prodrug of TRE. In this report, we have investigated mechanisms involved in TRE- and TP-induced cough, using a dry powder
Richard W. Chapman   +10 more
doaj   +1 more source

Tachykinin Agonists Modulate Cholinergic Neurotransmission at Guinea-Pig Intracardiac Ganglia

open access: yesJournal of Pharmacological Sciences, 2005
Effects of substance P (SP) and selective tachykinin agonists on neurotransmission at guinea-pig intracardiac ganglia were studied in vitro. Voltage responses of neurons to super-fused tachykinins and nerve stimulation were measured using intracellular ...
Lili Zhang   +2 more
doaj   +1 more source

Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

open access: yesFrontiers in Pharmacology, 2020
The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking.
Takafumi Hayashi   +7 more
doaj   +1 more source

Neuropeptides and G-Protein Coupled Receptors (GPCRs) in the Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Dryophthoridae)

open access: yesFrontiers in Physiology, 2020
The red palm weevil Rhynchophorus ferrugineus is a devastating, invasive pest that causes serious damages to palm trees, and its invasiveness depends on its strong ability of physiological and behavioral adaptability.
He Zhang   +10 more
doaj   +1 more source

Gene expression changes of angiogenesis factors during basal skin cancer laser destruction [PDF]

open access: yesVestnik Dermatologii i Venerologii, 2023
Background. Basal cell carcinoma is the most widespread malignant skin neoplasm. Angiogenesis is critical for the growth and metastasis of malignant tumors. Aims.
Rifat R. Saytburkhanov   +6 more
doaj   +1 more source

Loperamide Inhibits Tachykinin NK3-Receptor-Triggered Serotonin Release Without Affecting NK2-Receptor-Triggered Serotonin Release From Guinea Pig Colonic Mucosa

open access: yesJournal of Pharmacological Sciences, 2005
The effect of loperamide on tachykinin NK2- and NK3-receptor-mediated 5-HT outflow from guinea pig colonic mucosa was investigated in vitro. The selective tachykinin NK2-receptor agonist [β-Ala8]-neurokinin A4–10 (βAla-NKA) or the selective NK3-receptor ...
Shu-ichi Kojima   +2 more
doaj   +1 more source

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