Results 11 to 20 of about 579,792 (173)

Tachykinin receptors in GtoPdb v.2023.1 [PDF]

, 2023
Tachykinin receptors (provisional nomenclature as recommended by NC-IUPHAR [91]) are activated by the endogenous peptides substance P (SP), neurokinin A (NKA; previously known as substance K, neurokinin α, neuromedin L), neurokinin B (NKB ...
Leeman, Susan E., Dombrowsky, Erin, Barrett, Jeffrey, Jeffrey Barrett, Coulson, Joseph, Erin Dombrowsky, Pranela Remeshwar, Joseph Coulson, Remeshwar, Pranela, Steven D. Douglas, Tung M. Fong, Heyward, Christa Y., Fong, Tung M., Christa Y. Heyward, Brenden Canning, Canning, Brenden, Susan E. Leeman, Douglas, Steven D.   +17 more
core   +1 more source

Suppressive Effects of Glycyrrhetinic Acid Derivatives on Tachykinin Receptor Activation and Hyperalgesia

Journal of Pharmacological Sciences, 2011
.: Glycyrrhetinic acid (GA), an aglycone of glycyrrhizin, isolated from the licorice root (Glycyrrhizia), and its semi-synthetic derivatives have a wide range of pharmacological effects. To investigate whether GA derivatives may be used as a new class of
Yuko Akasaka, Atsushi Sakai, Kumiko Takasu, Michiko Tsukahara, Akira Hatta, Hidenori Suzuki, Hideo Inoue   +6 more
doaj   +1 more source

Expression and function of human hemokinin-1 in human and guinea pig airways

Respiratory Research, 2010
Background Human hemokinin-1 (hHK-1) and endokinins are peptides of the tachykinin family encoded by the TAC4 gene. TAC4 and hHK-1 expression as well as effects of hHK-1 in the lung and airways remain however unknown and were explored in this study ...
Sage Edouard, Risse Paul-André, Buenestado Amparo, Naline Emmanuel, Grassin-Delyle Stanislas, Advenier Charles, Devillier Philippe   +6 more
doaj   +1 more source

Characterisation, localisation and expression of porcine TACR1, TACR2 and TACR3 genes

Veterinární Medicína, 2017
Substance P is involved in many physiological and pathophysiological processes. This functional diversity is mediated by three neurokinin receptor subtypes (NK1R, NK2R and NK3R) encoded by the TACR1, TACR2 and TACR3 genes, respectively.
A. Jakimiuk, P. Podlasz, M. Chmielewska-Krzesinska, K. Wasowicz   +3 more
doaj   +1 more source

Tachykinin receptors antagonism for asthma: a systematic review

BMC Pulmonary Medicine, 2011
Background Tachykinins substance P, neurokinin A and neurokinin B seem to account for asthma pathophysiology by mediating neurogenic inflammation and several aspects of lung mechanics.
Couto Nuno, Soares Raquel, Ramalho Renata, Moreira André   +3 more
doaj   +1 more source

Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

ERJ Open Research, 2021
Cough is induced by inhaled prostacyclin analogues including treprostinil (TRE), and, at higher doses, treprostinil palmitil (TP), a prodrug of TRE. In this report, we have investigated mechanisms involved in TRE- and TP-induced cough, using a dry powder
Richard W. Chapman, Michel R. Corboz, Carlos Fernandez, Eugene Sullivan, Andy Stautberg, Adam J. Plaunt, Donna M. Konicek, Vladimir Malinin, Zhili Li, David Cipolla, Walter Perkins   +10 more
doaj   +1 more source

Tachykinin Agonists Modulate Cholinergic Neurotransmission at Guinea-Pig Intracardiac Ganglia

Journal of Pharmacological Sciences, 2005
Effects of substance P (SP) and selective tachykinin agonists on neurotransmission at guinea-pig intracardiac ganglia were studied in vitro. Voltage responses of neurons to super-fused tachykinins and nerve stimulation were measured using intracellular ...
Lili Zhang, John C. Hancock, Donald B. Hoover   +2 more
doaj   +1 more source

Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

Frontiers in Pharmacology, 2020
The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking.
Takafumi Hayashi, Chizuko Watanabe, Soh Katsuyama, Yasuyuki Agatsuma, Damiana Scuteri, Giacinto Bagetta, Tsukasa Sakurada, Shinobu Sakurada   +7 more
doaj   +1 more source

Neuropeptides and G-Protein Coupled Receptors (GPCRs) in the Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Dryophthoridae)

Frontiers in Physiology, 2020
The red palm weevil Rhynchophorus ferrugineus is a devastating, invasive pest that causes serious damages to palm trees, and its invasiveness depends on its strong ability of physiological and behavioral adaptability.
He Zhang, He Zhang, Juan Bai, Juan Bai, Shuning Huang, Shuning Huang, Huihui Liu, Huihui Liu, Jintian Lin, Youming Hou, Youming Hou   +10 more
doaj   +1 more source

Involvement of tachykinin receptors in the sensitization to cow's milk proteins in guinea-pigs

, 1997
Involvement of tachykinin receptors in the sensitization to cow's milk proteins in guinea-pigs.
Fioramonti, Jean, Emonds-Alt, Xavier, Gay-Quéheillard, Jérôme, Garcia Villar, Rafael, Bueno, Lionel   +4 more
core   +3 more sources