Results 21 to 30 of about 579,792 (173)

Loperamide Inhibits Tachykinin NK3-Receptor-Triggered Serotonin Release Without Affecting NK2-Receptor-Triggered Serotonin Release From Guinea Pig Colonic Mucosa

Journal of Pharmacological Sciences, 2005
The effect of loperamide on tachykinin NK2- and NK3-receptor-mediated 5-HT outflow from guinea pig colonic mucosa was investigated in vitro. The selective tachykinin NK2-receptor agonist [β-Ala8]-neurokinin A4–10 (βAla-NKA) or the selective NK3-receptor ...
Shu-ichi Kojima, Masashi Ikeda, Yuichiro Kamikawa   +2 more
doaj   +1 more source

Gene expression changes of angiogenesis factors during basal skin cancer laser destruction [PDF]

Vestnik Dermatologii i Venerologii, 2023
Background. Basal cell carcinoma is the most widespread malignant skin neoplasm. Angiogenesis is critical for the growth and metastasis of malignant tumors. Aims.
Rifat R. Saytburkhanov, Dmitry A. Verbenko, Xenia I. Plakhova, Irina N. Kondrakhina, Ksenia M. Lagun, Elena V. Filonenko, Аlexey A. Кubanov   +6 more
doaj   +1 more source

Both exogenous 5-HT and endogenous 5-HT, released by fluoxetine, enhance distension evoked propulsion in guinea-pig ileum in vitro

Frontiers in Neuroscience, 2014
The roles of 5-HT3 and 5-HT4 receptors in the modulation of intestinal propulsion by luminal application of 5-HT and augmentation of endogenous 5-HT effects were studied in segments of guinea-pig ileum in vitro. Persistent propulsive contractions evoked
Rachel M Gwynne, Amanda J Clarke, John B Furness, Joel C Bornstein   +3 more
doaj   +1 more source

Involvement of neuronal tachykinin-like receptor at 86C in Drosophila disc repair via regulation of kynurenine metabolism

iScience, 2023
Summary: Neurons contribute to the regeneration of projected tissues; however, it remains unclear whether they are involved in the non-innervated tissue regeneration.
Soshiro Kashio, Shu Masuda, Masayuki Miura   +2 more
doaj   +1 more source

Morphological and Molecular Characterization of Human Dermal Lymphatic Collectors. [PDF]

PLoS ONE, 2016
Millions of patients suffer from lymphedema worldwide. Supporting the contractility of lymphatic collectors is an attractive target for pharmacological therapy of lymphedema. However, lymphatics have mostly been studied in animals, while the cellular and
Viktoria Hasselhof, Anastasia Sperling, Kerstin Buttler, Philipp Ströbel, Jürgen Becker, Thiha Aung, Gunther Felmerer, Jörg Wilting   +7 more
doaj   +1 more source

The presence of NK3 tachykinin receptors on rat uterus

, 1991
The NK3 agonist, senktide, induced a potent contraction of rat uterus in the presence of tetrodotoxin, atropine and indomethacin, or the tachykinin receptor antagonists L-659877 and [D-Pro4, D-Trp7,9,10] substance P (4–11).
Bernal, A.L., Nimmo, A.J., Barr, A.J., Watson, S.P.   +3 more
core   +1 more source

Bidirectional Regulation of Human Colonic Smooth Muscle Contractility by Tachykinin NK2 Receptors

Journal of Pharmacological Sciences, 2011
.: In this study, we attempted to clarify the mechanism of tachykinin-induced motor response in isolated smooth muscle preparations of the human colon. Fresh specimens of normal colon were obtained from patients suffering from colonic cancer.
Akihiro Nakamura, Takahiro Tanaka, Akio Imanishi, Makiko Kawamoto, Masao Toyoda, Gaku Mizojiri, Yasuhiro Tsukimi   +6 more
doaj   +1 more source

Substance P and NK-1R in Dengue: A First Serological Investigation. [PDF]

Health Sci Rep
ABSTRACT Background Dengue fever lacks reliable biomarkers to explain its complex pathophysiology. Substance P (SP) and its receptor, the Neurokinin‐1 receptor (NK1R), known regulators of inflammation and vascular permeability in viral infections, may play a role in dengue but remain unexplored. Aim/Objective To investigate the levels of SP and NK1R in
Mehboob R, Shahid I, Ahmad S, Sarwar N, John A, Mehboob Z, Almansouri M, Badoghaish W.   +7 more
europepmc   +2 more sources

Localization of octopamine receptors, tachykinin, and tachykinin receptors in the antennae of P. americana.

, 2013
(A) Partial amino acid sequence of tachykinin receptors of Periplaneta americana (PaTKR) and its alignment with other insect tachykinin receptors present in mosquito (Aedes aegypti), honey bee (Apis mellifera), fruit fly (Drosophila melanogaster), red ...
Je Won Jung (121755), Hyung Wook Kwon (121757), Jin-Hee Kim (484785), Rita Pfeiffer (484786), Young-Joon Ahn (403478), Terry L. Page (393219)   +5 more
core   +1 more source

Neurokinin receptors in the gastrointestinal muscle wall: cell distribution and possible roles

Biomolecular Concepts, 2013
The neurokinin receptors are G-protein-linked receptors; three distinct molecules, called neurokinin-1, neurokinin-2, and neurokinin-3 receptors, have been identified.
Vannucchi Maria Giuliana, Evangelista Stefano   +1 more
doaj   +1 more source