Results 11 to 20 of about 4,888 (209)

Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]

open access: yesJournal of Occupational Medicine and Toxicology, 2008
Background Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg David A   +3 more
doaj   +2 more sources

Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on NeuroinflammationSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2018
Background & Aims: Tachykinins are involved in physiological and pathophysiological mechanisms in the gastrointestinal tract. The major sources of tachykinins in the gut are intrinsic enteric neurons in the enteric nervous system and extrinsic nerve ...
Ninotchska M. Delvalle   +5 more
doaj   +2 more sources

Tachykinins stimulate a subset of mouse taste cells. [PDF]

open access: yesPLoS ONE, 2012
The tachykinins substance P (SP) and neurokinin A (NKA) are present in nociceptive sensory fibers expressing transient receptor potential cation channel, subfamily V, member 1 (TRPV1).
Jeff Grant
doaj   +2 more sources

Tachykinins and the potential causal factors for post-COVID-19 condition. [PDF]

open access: yesLancet Microbe, 2023
The most prevalent symptoms of post-COVID-19 condition are pulmonary dysfunction, fatigue and muscle weakness, anxiety, anosmia, dysgeusia, headaches, difficulty in concentrating, sexual dysfunction, and digestive disturbances.
Janket SJ   +7 more
europepmc   +2 more sources

Substance P and NK-1R in Dengue: A First Serological Investigation. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background Dengue fever lacks reliable biomarkers to explain its complex pathophysiology. Substance P (SP) and its receptor, the Neurokinin‐1 receptor (NK1R), known regulators of inflammation and vascular permeability in viral infections, may play a role in dengue but remain unexplored. Aim/Objective To investigate the levels of SP and NK1R in
Mehboob R   +7 more
europepmc   +2 more sources

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology. [PDF]

open access: yesJ Exp Zool A Ecol Integr Physiol
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Cuchillo-Hilario M   +3 more
europepmc   +2 more sources

Age-Related Decreases in Colonic Neurokinin A Content and Release Monitored Using Electrochemical Immunosensors. [PDF]

open access: yesNeurogastroenterol Motil
A 3D‐printed electrochemical immunosensor revealed significant age‐related reductions in colonic Neurokinin A (NKA) content and release. Decreased fecal NKA levels mirrored tissue changes, highlighting the potential of NKA as a noninvasive biomarker of age‐related bowel dysfunction.
Miller C, Yeoman M, Patel BA.
europepmc   +2 more sources

Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus

open access: yesReproductive Biology and Endocrinology, 2009
Background In the mouse uterus, pregnancy is accompanied by changes in tachykinin and tachykinin receptor gene expression and in the uterotonic effects of endogenous tachykinins. In this study we have investigated whether changes in tachykinin expression
Patak Eva   +4 more
doaj   +1 more source

Blockade of NK-1 receptors in the lateral commissural nucleus tractus solitarii of awake rats had no effect on the cardiovascular responses to chemoreflex activation

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The neurotransmission of the chemoreflex in the nucleus tractus solitarii (NTS), particularly of the sympatho-excitatory component, is not completely understood.
C. Zhang, L.G.H. Bonagamba, B.H. Machado
doaj   +1 more source

Tachykinins modulate nociceptive responsiveness and sensitization: In vivo electrical characterization of primary sensory neurons in tachykinin knockout (Tac1 KO) mice

open access: yesMolecular Pain, 2019
Since the failure of specific substance P antagonists to induce analgesia, the role of tachykinins in the development of neuropathic pain states has been discounted.
Silvia Gutierrez   +4 more
doaj   +1 more source

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