Results 61 to 70 of about 5,966,929 (265)

Silent neurological involvement in biopsy-defined coeliac patients

, 2013
Coeliac disease (CD) is an autoimmune disease of small intestine associated with sensitivity to gluten. The clinical manifestations are often of gastrointestinal nature, although the disease may be present asymptomatically as well.
Hanagasi, Haşmet Ayhan, BAYRAM, ALİ, Bilgic, Başar, Akyuz, Filiz, Sencer, Serra, Arslan, Ali Bilgin, Aygun, Demet   +6 more
core   +1 more source

Permanent Neurological Damage Due To Trauma: An Important Conclusion in Forensic Medicine [PDF]

, 2013
Amaç: Travma sonrası mağdurda ortaya çıkan yaralanmanın şiddetinin belirlenmesi, sanığa ceza verilip verilmeyeceği, verilecek ise ceza artırımına gidilip gidilmeyeceği konusunda önemli rol oynar.
Kumral, Bahadır, Oğuz, Keriman, Gündoğmuş, Ümit Naci, Ünal, Aysun   +3 more
core   +1 more source

Circadian disruption and sleep disorders in neurodegeneration

Translational Neurodegeneration, 2023
Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional relationship between disruptions of circadian rhythms and sleep cycles and ...
Yun Shen, Qian-kun Lv, Wei-ye Xie, Si-yi Gong, Sheng Zhuang, Jun-yi Liu, Cheng-jie Mao, Chun-feng Liu   +7 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A hybrid random forest model for stroke risk prediction

Frontiers in Neurology
ObjectivesOur study aims to develop a stroke risk prediction model by multiple machine learning algorithms and optimize the model as a stroke risk prediction tool.MethodsThis retrospective multicenter study derived the original dataset from a high ...
Qixuan Lu, Shuo Li, Hongyuan Xu, Hui Shen, Yufei Wei, Yufei Wei   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Nuclear pore and nucleocytoplasmic transport impairment in oxidative stress-induced neurodegeneration: relevance to molecular mechanisms in Pathogenesis of Parkinson’s and other related neurodegenerative diseases

Molecular Neurodegeneration
Nuclear pore complexes (NPCs) are embedded in the nuclear envelope and facilitate the exchange of macromolecules between the nucleus and cytoplasm in eukaryotic cells. The dysfunction of the NPC and nuclear transport plays a significant role in aging and
Zainab Riaz, Gabriel S. Richardson, Huajun Jin, Gary Zenitsky, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Standards of care for people with disabling (progressive and static) neurological conditions in the hospital and community: standards of care for people with disabling progressive and static neurological conditions in the hospital and community.

, 2001
Neurological conditions are common, affecting over 500,000 people in the Irish population. Recent advances in the neurosciences have improved the outlook many conditions, as major breakthroughs have been achieved. Standing pathogenesis, the prospect of
Neurological Alliance of Ireland
core