Results 1 to 10 of about 1,065,066 (238)
Neurosteroids and neurological disorders. [PDF]
Korean J Physiol PharmacolNeurosteroids play an important role as endogenous neuromodulators that are locally produced in the central nervous system and rapidly change the excitability of neurons and the activation of microglial cells and astrocytes. Here we review the mechanisms of synthesis, metabolism, and actions of neurosteroids in the central nervous system. Neurosteroids
Park GW, Kim H, Won SH, Kim NH, Choi SR.
europepmc +3 more sources
Mitophagy in neurological disorders [PDF]
Journal of Neuroinflammation, 2021 AbstractSelective autophagy is an evolutionarily conserved mechanism that removes excess protein aggregates and damaged intracellular components. Most eukaryotic cells, including neurons, rely on proficient mitophagy responses to fine-tune the mitochondrial number and preserve energy metabolism. In some circumstances (such as the presence of pathogenic
Lijun Zhang, Lei Dai, Deyuan Li
openaire +3 more sources
Clinical advances in oncolytic virus therapy for malignant glioma: a systematic review
Discover Oncology, 2023 Purpose In the past decade, there has been little progress in the treatment of malignant glioma. Recently, oncolytic virus has made great progress in glioma treatment, and a number of clinical trials have shown their potential of prolonging the survival ...
Shan Jiang +4 more
doaj +1 more source
BMC Medicine, 2023 Background Previous studies have found a correlation between coronavirus disease 2019 (COVID-19) and changes in brain structure and cognitive function, but it remains unclear whether COVID-19 causes brain structural changes and which specific brain ...
Shaojiong Zhou +8 more
doaj +1 more source
Fluids and Barriers of the CNS, 2023 Background The blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor mediated transport systems, such as the transferrin receptor, can be used to carry macromolecular cargos ...
Thomas J. Esparza +5 more
doaj +1 more source
Nutraceuticals in Neurological Disorders [PDF]
International Journal of Molecular Sciences, 2020 Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes are associated with drastically increased risk of chronic illness and diseases, posing a substantial healthcare and financial burden to society globally. Researchers aim to provide fine treatment for ailing disorders with minimal exposed side effects.
Rashita Makkar +10 more
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Molecular Neurodegeneration, 2022 Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane immune receptor that is mainly expressed on microglia in the brain and macrophages in the periphery.
Rui-Yang Li +8 more
doaj +1 more source
Brain and Behavior, 2023 Background The incidence of gastroesophageal reflux disease (GERD) has been shown to be elevated in individuals with epilepsy. Traditional observational studies have led to a limited understanding of the effects of GERD and BE on epilepsy due to the ...
Xiaoduo Liu +8 more
doaj +1 more source
Neurological disorder? No, Mannerism [PDF]
The Lancet Neurology, 2019 Analysis of the relationship between art and medicine, in the identification of diseases in works of ...
Donatella Lippi +6 more
openaire +6 more sources
Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]
, 2020 Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul +6 more
core +2 more sources