Results 21 to 30 of about 2,206,438 (308)

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation

open access: yesCommunications Biology, 2021
Pathak et al. identify LDB3, a striated muscle PDZ-LIM protein, as a signaling adaptor in a major mechanosensor assembly through interactions with filamin C, HSPA8, and PKCα.
Pankaj Pathak   +11 more
doaj   +1 more source

Poststroke neurological improvement within 7 days is associated with subsequent deterioration [PDF]

open access: yes, 2004
<p><b>Background and Purpose:</b> Improvement in the National Institutes of Health Stroke Scale (NIHSS) 24 hours after stroke has been associated with subsequent neurological deterioration.
ASLANYAN S   +10 more
core   +2 more sources

Scaling up services for mental and neurological disorders in low-resource settings. [PDF]

open access: yes, 2009
Mental and neurological disorders (MNDs) account for a large, and growing, burden of disease in low- and middle-income countries. Most people do not have access to even basic health care for these disorders.
Vikram Patel   +5 more
core   +2 more sources

Real-time visualization of exo- and endocytosis membrane dynamics with confocal and super-resolution microscopy

open access: yesSTAR Protocols, 2022
Summary: Real-time confocal and super-resolution imaging reveals membrane dynamics of exo- and endocytosis, including hemi-fusion, fusion pore opening, expansion, constriction, closure (kiss-and-run), fused-vesicle shrinking (shrink fusion), and flat ...
Xiaoli Guo   +6 more
doaj   +1 more source

Genomics in Neurological Disorders

open access: yesGenomics, Proteomics & Bioinformatics, 2014
Abstract Neurological disorders comprise a variety of complex diseases in the central nervous system, which can be roughly classified as neurodegenerative diseases and psychiatric disorders. The basic and translational research of neurological disorders has been hindered by the difficulty in accessing the pathological center (i.e., the ...
Guangchun Han   +5 more
openaire   +4 more sources

Nutritional interventions for the prevention and treatment of neurological disorders such as anxiety, bipolar disorder, depression, epilepsy, multiple sclerosis, and schizophrenia

open access: yes, 2022
Neurological disorders are a significant cause of mortality and disability across the world. The current aging population and population expansion have seen an increase in the prevalence of neurological and psychiatric disorders such as anxiety, bipolar ...
Sahithi Madireddy*, Samskruthi Madireddy
core   +1 more source

[Functional Neurological Disorders - A Common but Often Unrecognized Diagnosis].

open access: yes, 2023
Functional Neurological Disorders - A Common but Often Unrecognized Diagnosis Abstract: Functional neurological disorders are frequent and diverse in the clinical presentation.
Gegusch, Michaela, Barth, Rike
core   +1 more source

Photophobia in neurologic disorders [PDF]

open access: yesTranslational Neurodegeneration, 2017
Photophobia is a common symptom seen in many neurologic disorders, however, its pathophysiology remains unclear. Even the term is ambiguous. In this paper, we review the epidemiology and clinical manifestations of photophobia in neurological disorders, including primary headache, blepharospasm, progressive supranuclear palsy, and traumatic brain injury,
Yiwen Wu, Mark Hallett
openaire   +3 more sources

Development and validation of tools for the asssessment of the burden and disease-management of headache disorders in Europe [PDF]

open access: yes, 2009
Headache, including migraine, is a common and disabling neurobiological disorder which is under-recognized, under-treated, commonly mismanaged and it imposes a substantial health burden.
Andrée, Colette Marie
core   +1 more source

Periictal water drinking revisited: Occurrence and lateralizing value in surgically confirmed patients with focal epilepsy

open access: yesEpilepsia Open, 2023
Objective Periictal water drinking (PIWD), which is a rare seizure‐related autonomic behavior, has been reported in temporal lobe epilepsy (TLE) but only rarely in extra‐TLE. Additionally, the lateralizing value of PIWD is controversial.
Yuhei Tanno   +8 more
doaj   +1 more source

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