Results 31 to 40 of about 2,302,356 (314)

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study

Journal of Neuroinflammation, 2022
Background Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases.
Xiaolei Shi, Tao Wei, Yachun Hu, Meng Wang, Yi Tang   +4 more
doaj   +1 more source

National Institute of Neurological Disorders and Stroke FIVE-YEAR STRATEGIC PLAN ON MINORITY HEALTH DISPARITIES

, 2002
The National Institute of Neurological Disorders and Stroke (NINDS) is the lead agency for basic and clinical research focused on the brain, spinal cord, and peripheral nerves; their development, degeneration, and regeneration; and their disorders and ...
National Institute of, Neurological Disorders and Stroke
core   +1 more source

Olfactory sensory activity modulates microglial-neuronal interactions during dopaminergic cell loss in the olfactory bulb

Frontiers in Cellular Neuroscience, 2016
The mammalian olfactory bulb (OB) displays robust activity-dependent plasticity throughout life. Dopaminergic (DA) neurons in the glomerular layer (GL) of the OB are particularly plastic, with loss of sensory input rapidly reducing tyrosine hydroxylase ...
Bryce Davis Grier, Leonardo Belluscio, Claire Elizabeth Jane Cheetham   +2 more
doaj   +1 more source

Blood-brain barrier integrity of stroke patients presenting in an extended time window

BMC Neurology, 2020
Background Current guidelines limit thrombolytic treatment of stroke to those patients who present within 4.5 h to minimize the risk of hemorrhagic complications. Risk of hemorrhage increases with increasing blood-brain barrier (BBB) disruption.
Jarrhett Butler, Parisa Heidari, Sarah Blayney, Emi Hitomi, Marie Luby, Richard Leigh   +5 more
doaj   +1 more source

Challenges and Perspectives of Neurological Disorders

, 2023
Neurological disorders pose significant challenges to healthcare systems worldwide [...
Dina Nur Anggraini Ningrum, Woon-Man Kung   +1 more
core   +1 more source

HHV‐6 and hippocampal volume in patients with mesial temporal sclerosis

Annals of Clinical and Translational Neurology, 2020
Objective To study the effects of human herpes virus 6 (HHV‐6) on the hippocampal volume in patients with mesial temporal sclerosis (MTS). Background HHV‐6 may play an etiologic role in MTS.
Elizabeth O. Akinsoji, Emily Leibovitch, B. Jeanne Billioux, Osorio Lopes Abath Neto, Abhik Ray‐Chaudhury, Sara K. Inati, Kareem Zaghloul, John Heiss, Steven Jacobson, William H. Theodore   +9 more
doaj   +1 more source

Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance

eLife, 2022
The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the action of a V-type H+ ATPase, but other pathways for ion movement are required to dissipate the ...
Xavier Leray, Jacob K Hilton, Kamsi Nwangwu, Alissa Becerril, Vedrana Mikusevic, Gabriel Fitzgerald, Anowarul Amin, Mary R Weston, Joseph A Mindell   +8 more
doaj   +1 more source

Burden of neurological disorders in China and its provinces, 1990–2021: Findings from the global burden of disease study 2021 [PDF]

Background: The burden of neurological disorders in China has not been systematically analyzed. We aim to provide a comprehensive estimation of the national and subnational neurological burden across China from the Global Burden of Disease Study (GBD ...
Ma, Q, Yang, Xuan, Neurological Disorders Collabo, GBD 2021 China, Hao, J, Kisa, Adnan, Yin, P, Zhang, Chen, Kisa, Sezer, Yang, X, Ma, Qingfeng, Guo, Cui, Yin, Peng, GBD 2021 China Neurological Disorders Collaborators, Wan, D, Zhang, C, Zhou, Maigeng, Hao, Junwei, Wan, Dongshan, Zhou, M, Alshahrani, Najim Z., Anil, Abhishek, Addo, Isaac Yeboah, Adra, Saryia, Bai, Ruhai, Azzam, Ahmed Y., Bastan, Mohammad Mahdi, Agyemang-Duah, Williams, Chong, Bryan, Babu, Giridhara Rathnaiah, Nguyen, Van Thanh, Ahmed, Syed Anees, Anyasodor, Anayochukwu Edward, Alif, Sheikh Mohammad, Akkaif, Mohammed Ahmed, Ali, Waad, GBD 2021 China Neurological Disorders Collaborators,, Bashiru, Hameed Akande, Abu-Zaid, Ahmed, Atreya, Alok, Liu, Xiaofeng, Postma, Maarten J.; id_orcid, Bashiri, Azadeh, Al-Wardat, Mohammad, Cerin, Ester, Ali, Abid, Amiri, Sohrab, Algammal, Abdelazeem M., Chen, Hui, Astell-Burt, Thomas, Ali, Mohammed Usman, Bhagavathula, Akshaya Srikanth, Aziz, Shahkaar, Chattu, Vijay Kumar, Ahmad, Danish, Bhattacharjee, Priyadarshini, Bako, Abdulaziz T., Bhaskar, Sonu, Mubarik, Sumaira; id_orcid, Balakrishnan, Senthilkumar, Bahramian, Saeed, Ahmed, Ayman, Cao, Fan   +61 more
core   +1 more source

Neurological sleep disorders

, 2023
This review summarises the current knowledge of neurological sleep disorders. These disorders are frequent and involve a number of serious diseases associated with complications or precede other serious brain diseases.
Jennum, Poul Jørgen, Asah, Cresta, Frandsen, Rune   +2 more
core   +1 more source

Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA mutation carriers

npj Parkinson's Disease, 2022
Non-manifesting carriers (NMCs) of Parkinson’s disease (PD)-related mutations such as LRRK2 and GBA are at an increased risk for developing PD. Dopamine transporter (DaT)-spectral positron emission computed tomography is widely used for capturing ...
Amgad Droby, Moran Artzi, Hedva Lerman, R. Matthew Hutchison, Dafna Ben Bashat, Nurit Omer, Tanya Gurevich, Avi Orr-Urtreger, Batsheva Cohen, Jesse M. Cedarbaum, Einat Even Sapir, Nir Giladi, Anat Mirelman, Avner Thaler   +13 more
doaj   +1 more source