Results 11 to 20 of about 4,670,463 (363)
Frontiers in Public Health, 2022 Background Neurological disorders are a major and increasing global health challenge, which accounts for a substantial portion of the disease burden worldwide.
Chenyu Ding, Fa Chen, Ding Chenyu
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Mesenchymal Stem Cells for Neurological Disorders
Advanced Science, 2021 Neurological disorders are becoming a growing burden as society ages, and there is a compelling need to address this spiraling problem. Stem cell‐based regenerative medicine is becoming an increasingly attractive approach to designing therapies for such ...
Sylwia Da̧Browska +2 more
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EClinicalMedicine, 2021 Background Coronavirus disease 2019 (COVID-19) has evolved into a worldwide pandemic, and has been found to be closely associated with mental and neurological disorders. We aimed to comprehensively quantify the association between mental and neurological
Lin Liu, Huan Mei, Le Shi
exaly +2 more sources
Mitophagy in neurological disorders [PDF]
Journal of Neuroinflammation, 2021 AbstractSelective autophagy is an evolutionarily conserved mechanism that removes excess protein aggregates and damaged intracellular components. Most eukaryotic cells, including neurons, rely on proficient mitophagy responses to fine-tune the mitochondrial number and preserve energy metabolism. In some circumstances (such as the presence of pathogenic
Lijun Zhang, Lei Dai, Deyuan Li
openaire +3 more sources
Clinical advances in oncolytic virus therapy for malignant glioma: a systematic review
Discover Oncology, 2023 Purpose In the past decade, there has been little progress in the treatment of malignant glioma. Recently, oncolytic virus has made great progress in glioma treatment, and a number of clinical trials have shown their potential of prolonging the survival ...
Shan Jiang +4 more
doaj +1 more source
The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders.
Pharmacological Research, 2021 Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional communication between the gut and the brain suggesting that gut microbes may shape neural development, modulate neurotransmission and affect behavior, and ...
K. Socała +8 more
semanticscholar +1 more source
BMC Medicine, 2023 Background Previous studies have found a correlation between coronavirus disease 2019 (COVID-19) and changes in brain structure and cognitive function, but it remains unclear whether COVID-19 causes brain structural changes and which specific brain ...
Shaojiong Zhou +8 more
doaj +1 more source
Journal of Global Health, 2023 Background We aimed to determine the incidence and disability-adjusted life-years (DALYs) of neurological disorders worldwide from 1990 to 2019. Methods We obtained age-standardised incidence and DALY rates of neurological disorders in 204 countries and ...
Yi Huang +3 more
semanticscholar +1 more source
Fluids and Barriers of the CNS, 2023 Background The blood brain barrier limits entry of macromolecular diagnostic and therapeutic cargos. Blood brain barrier transcytosis via receptor mediated transport systems, such as the transferrin receptor, can be used to carry macromolecular cargos ...
Thomas J. Esparza +5 more
doaj +1 more source
Glycosylation and behavioral symptoms in neurological disorders
Translational Psychiatry, 2023 Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is a complex post-translational modification that plays a crucial role in cellular function.
Prajitha Pradeep +2 more
semanticscholar +1 more source