Results 11 to 20 of about 663,441 (269)

Real-time visualization of exo- and endocytosis membrane dynamics with confocal and super-resolution microscopy

STAR Protocols, 2022
Summary: Real-time confocal and super-resolution imaging reveals membrane dynamics of exo- and endocytosis, including hemi-fusion, fusion pore opening, expansion, constriction, closure (kiss-and-run), fused-vesicle shrinking (shrink fusion), and flat ...
Xiaoli Guo, Sue Han, Lisi Wei, Gianvito Arpino, Wonchul Shin, Xin Wang, Ling-Gang Wu   +6 more
doaj   +1 more source

Genomics in Neurological Disorders

Genomics, Proteomics & Bioinformatics, 2014
Abstract Neurological disorders comprise a variety of complex diseases in the central nervous system, which can be roughly classified as neurodegenerative diseases and psychiatric disorders. The basic and translational research of neurological disorders has been hindered by the difficulty in accessing the pathological center (i.e., the ...
Guangchun Han, Jiya Sun, Jiajia Wang, Zhouxian Bai, Fuhai Song, Hongxing Lei   +5 more
openaire   +3 more sources

Neurological disorder in pregnancy

Romanian Journal of Medical Practice, 2018
Bell facial paralysis association with pregnancy pathology is quite rare in practice, but reported to the cases outside gestation it is 2 times more frequent, which was why we decided to present this case. In the presented case, we note that the neurological pathology was revealed in a patient, aged 34 years and located in 34 weeks gestation with ...
Elena Mihai Zamfir, Anca Daniela Braila, Mihai Braila, Radu Nicolae Mateescu, Antoine Edu   +4 more
openaire   +2 more sources

Periictal water drinking revisited: Occurrence and lateralizing value in surgically confirmed patients with focal epilepsy

Epilepsia Open, 2023
Objective Periictal water drinking (PIWD), which is a rare seizure‐related autonomic behavior, has been reported in temporal lobe epilepsy (TLE) but only rarely in extra‐TLE. Additionally, the lateralizing value of PIWD is controversial.
Yuhei Tanno, Takashi Matsudaira, Naotaka Usui, Hiroshi Ogawa, Kentaro Tokumoto, Norihiko Kawaguchi, Akihiko Kondo, Takuji Nishida, Yukitoshi Takahashi   +8 more
doaj   +1 more source

Recent Advancement of Neurofibromatosis Type 1: A Narrative Review

Acta Neurologica Taiwanica
Neurofibromatosis type 1 (NF1) is a complex autosomal dominant genetic disorder caused by mutations in the NF1 gene on chromosome 17, which encodes the tumor-suppressor protein, neurofibromin.
Po-Yuan Huang, Society for Neurological Rare Disorders-Taiwan, Ming-Jen Lee   +2 more
doaj   +1 more source

Development of a sensitive outcome for economical drug screening for progressive multiple sclerosis treatment

Frontiers in Neurology, 2016
Therapeutic advance in progressive multiple sclerosis (MS) has been very slow. Based on the transformative role magnetic resonance imaging (MRI) contrast-enhancing lesions had on drug development for relapsing-remitting MS, we consider the lack of ...
Peter Kosa, Danish Ghazali, Makoto Tanigawa, Chris Barbour, Irene Cortese, William Kelley, Blake Snyder, Joan Ohayon, Kaylan Fenton, Tanya Lehky, Tianxia Wu, Mark Greenwood, Govind Nair, Bibiana Bielekova   +13 more
doaj   +1 more source

A Review of Spinocerebellar Ataxias in Taiwan

Acta Neurologica Taiwanica
Spinocerebellar ataxias (SCAs) are a group of neurodegenerative diseases characterized by inherited progressive cerebellar ataxia with or without other associated features. The clinical presentations of these affected SCA patients are very heterogeneous.
Chia-Ju Lee, Chin-San Liu, Society for Neurological Rare Disorders-Taiwan   +2 more
doaj   +1 more source

Blood-brain barrier integrity of stroke patients presenting in an extended time window

BMC Neurology, 2020
Background Current guidelines limit thrombolytic treatment of stroke to those patients who present within 4.5 h to minimize the risk of hemorrhagic complications. Risk of hemorrhage increases with increasing blood-brain barrier (BBB) disruption.
Jarrhett Butler, Parisa Heidari, Sarah Blayney, Emi Hitomi, Marie Luby, Richard Leigh   +5 more
doaj   +1 more source

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study

Journal of Neuroinflammation, 2022
Background Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases.
Xiaolei Shi, Tao Wei, Yachun Hu, Meng Wang, Yi Tang   +4 more
doaj   +1 more source

Olfactory sensory activity modulates microglial-neuronal interactions during dopaminergic cell loss in the olfactory bulb

Frontiers in Cellular Neuroscience, 2016
The mammalian olfactory bulb (OB) displays robust activity-dependent plasticity throughout life. Dopaminergic (DA) neurons in the glomerular layer (GL) of the OB are particularly plastic, with loss of sensory input rapidly reducing tyrosine hydroxylase ...
Bryce Davis Grier, Leonardo Belluscio, Claire Elizabeth Jane Cheetham   +2 more
doaj   +1 more source