Results 11 to 20 of about 1,032,345 (337)

Mitophagy in neurological disorders [PDF]

open access: yesJournal of Neuroinflammation, 2021
AbstractSelective autophagy is an evolutionarily conserved mechanism that removes excess protein aggregates and damaged intracellular components. Most eukaryotic cells, including neurons, rely on proficient mitophagy responses to fine-tune the mitochondrial number and preserve energy metabolism. In some circumstances (such as the presence of pathogenic
Lijun Zhang, Lei Dai, Deyuan Li
openaire   +3 more sources

Nutraceuticals in Neurological Disorders [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes are associated with drastically increased risk of chronic illness and diseases, posing a substantial healthcare and financial burden to society globally. Researchers aim to provide fine treatment for ailing disorders with minimal exposed side effects.
Rashita Makkar   +10 more
openaire   +3 more sources

Neurological disorder? No, Mannerism [PDF]

open access: yesThe Lancet Neurology, 2019
Analysis of the relationship between art and medicine, in the identification of diseases in works of ...
Donatella Lippi   +6 more
openaire   +6 more sources

Photophobia in neurologic disorders [PDF]

open access: yesTranslational Neurodegeneration, 2017
Photophobia is a common symptom seen in many neurologic disorders, however, its pathophysiology remains unclear. Even the term is ambiguous. In this paper, we review the epidemiology and clinical manifestations of photophobia in neurological disorders, including primary headache, blepharospasm, progressive supranuclear palsy, and traumatic brain injury,
Mark Hallett, Yiwen Wu
openaire   +3 more sources

Apheresis in Neurological Disorders [PDF]

open access: yesJournal of Clinical Medicine, 2020
Plasma exchange (PE) and immunoadsorption (IA) constitute important options in the treatment of various autoimmune disorders across different medical disciplines [...]
openaire   +4 more sources

Neurosteroids and neurological disorders. [PDF]

open access: yesKorean J Physiol Pharmacol
Neurosteroids play an important role as endogenous neuromodulators that are locally produced in the central nervous system and rapidly change the excitability of neurons and the activation of microglial cells and astrocytes. Here we review the mechanisms of synthesis, metabolism, and actions of neurosteroids in the central nervous system. Neurosteroids
Park GW, Kim H, Won SH, Kim NH, Choi SR.
europepmc   +3 more sources

Genomics in Neurological Disorders

open access: yesGenomics, Proteomics & Bioinformatics, 2014
Abstract Neurological disorders comprise a variety of complex diseases in the central nervous system, which can be roughly classified as neurodegenerative diseases and psychiatric disorders. The basic and translational research of neurological disorders has been hindered by the difficulty in accessing the pathological center (i.e., the ...
Guangchun Han   +9 more
openaire   +4 more sources

Global, regional, and national burden of neurological disorders, 1990–2016 : a systematic analysis for the Global Burden of Disease Study 2016 [PDF]

open access: yes, 2019
Background Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most ...
Gill, Paramjit, HASH(0x55f51390f3f8)
core   +1 more source

Enteral feeding in neurological disorders [PDF]

open access: yes, 2016
Malnutrition and weight loss, due to suboptimal oral intake, are common in patients with neurological disorders, and associated with increased morbidity, disability and mortality. The nutritional management of neurological patients is crucial and enteral
McDermott, C.J., Stavroulakis, T.
core   +1 more source

Development of a sensitive outcome for economical drug screening for progressive multiple sclerosis treatment

open access: yesFrontiers in Neurology, 2016
Therapeutic advance in progressive multiple sclerosis (MS) has been very slow. Based on the transformative role magnetic resonance imaging (MRI) contrast-enhancing lesions had on drug development for relapsing-remitting MS, we consider the lack of ...
Peter Kosa   +13 more
doaj   +1 more source

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