Results 21 to 30 of about 1,108,914 (332)

The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study

Journal of Neuroinflammation, 2022
Background Triggering receptor expressed on myeloid cell 1 (Trem1) is an important regulator of cellular inflammatory responses. Neuroinflammation is a common thread across various neurological diseases.
Xiaolei Shi, Tao Wei, Yachun Hu, Meng Wang, Yi Tang   +4 more
doaj   +1 more source

Neurological Disorders in Primary Sjögren's Syndrome. [PDF]

, 2012
International audienceSjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands.
Devauchelle-Pensec, Valérie, Pers, Jacques-Olivier, Tobón, Gabriel J, Youinou, Pierre   +3 more
core   +5 more sources

Recent Advancement of Neurofibromatosis Type 1: A Narrative Review

Acta Neurologica Taiwanica
Neurofibromatosis type 1 (NF1) is a complex autosomal dominant genetic disorder caused by mutations in the NF1 gene on chromosome 17, which encodes the tumor-suppressor protein, neurofibromin.
Po-Yuan Huang, Society for Neurological Rare Disorders-Taiwan, Ming-Jen Lee   +2 more
doaj   +1 more source

Blood-brain barrier integrity of stroke patients presenting in an extended time window

BMC Neurology, 2020
Background Current guidelines limit thrombolytic treatment of stroke to those patients who present within 4.5 h to minimize the risk of hemorrhagic complications. Risk of hemorrhage increases with increasing blood-brain barrier (BBB) disruption.
Jarrhett Butler, Parisa Heidari, Sarah Blayney, Emi Hitomi, Marie Luby, Richard Leigh   +5 more
doaj   +1 more source

Italian Wikipedia and epilepsy: an infodemiological study of online information-seeking behavior [PDF]

, 2018
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related ...
Bragazzi, Nicola Luigi, Brigo, Francesco, Galimberti, Carlo Andrea, Giussani, Giorgia, Lattanzi, Simona, Mecarelli, Oriano, Nardone, Raffaele, Pietrafusa, Nicola, Tassi, Laura   +8 more
core   +1 more source

A Review of Spinocerebellar Ataxias in Taiwan

Acta Neurologica Taiwanica
Spinocerebellar ataxias (SCAs) are a group of neurodegenerative diseases characterized by inherited progressive cerebellar ataxia with or without other associated features. The clinical presentations of these affected SCA patients are very heterogeneous.
Chia-Ju Lee, Chin-San Liu, Society for Neurological Rare Disorders-Taiwan   +2 more
doaj   +1 more source

Olfactory sensory activity modulates microglial-neuronal interactions during dopaminergic cell loss in the olfactory bulb

Frontiers in Cellular Neuroscience, 2016
The mammalian olfactory bulb (OB) displays robust activity-dependent plasticity throughout life. Dopaminergic (DA) neurons in the glomerular layer (GL) of the OB are particularly plastic, with loss of sensory input rapidly reducing tyrosine hydroxylase ...
Bryce Davis Grier, Leonardo Belluscio, Claire Elizabeth Jane Cheetham   +2 more
doaj   +1 more source

HHV‐6 and hippocampal volume in patients with mesial temporal sclerosis

Annals of Clinical and Translational Neurology, 2020
Objective To study the effects of human herpes virus 6 (HHV‐6) on the hippocampal volume in patients with mesial temporal sclerosis (MTS). Background HHV‐6 may play an etiologic role in MTS.
Elizabeth O. Akinsoji, Emily Leibovitch, B. Jeanne Billioux, Osorio Lopes Abath Neto, Abhik Ray‐Chaudhury, Sara K. Inati, Kareem Zaghloul, John Heiss, Steven Jacobson, William H. Theodore   +9 more
doaj   +1 more source

Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance

eLife, 2022
The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the action of a V-type H+ ATPase, but other pathways for ion movement are required to dissipate the ...
Xavier Leray, Jacob K Hilton, Kamsi Nwangwu, Alissa Becerril, Vedrana Mikusevic, Gabriel Fitzgerald, Anowarul Amin, Mary R Weston, Joseph A Mindell   +8 more
doaj   +1 more source

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia, Giulivi, Cecilia, Napoli, Eleonora   +2 more
core   +1 more source