Results 31 to 40 of about 1,108,914 (332)

Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA mutation carriers

npj Parkinson's Disease, 2022
Non-manifesting carriers (NMCs) of Parkinson’s disease (PD)-related mutations such as LRRK2 and GBA are at an increased risk for developing PD. Dopamine transporter (DaT)-spectral positron emission computed tomography is widely used for capturing ...
Amgad Droby, Moran Artzi, Hedva Lerman, R. Matthew Hutchison, Dafna Ben Bashat, Nurit Omer, Tanya Gurevich, Avi Orr-Urtreger, Batsheva Cohen, Jesse M. Cedarbaum, Einat Even Sapir, Nir Giladi, Anat Mirelman, Avner Thaler   +13 more
doaj   +1 more source

Calcineurin Is Universally Involved in Vesicle Endocytosis at Neuronal and Nonneuronal Secretory Cells

Cell Reports, 2014
Calcium influx triggers and accelerates endocytosis in nerve terminals and nonneuronal secretory cells. Whether calcium/calmodulin-activated calcineurin, which dephosphorylates endocytic proteins, mediates this process is highly controversial for ...
Xin-Sheng Wu, Zhen Zhang, Wei-Dong Zhao, Dongsheng Wang, Fujun Luo, Ling-Gang Wu   +5 more
doaj   +1 more source

Guided self-help interventions for mental health disorders in children with neurological conditions: study protocol for a pilot randomised controlled [PDF]

, 2016
Background: Rates of mental health disorders are significantly greater in children with physical illnesses than in physically well children. Children with neurological conditions, such as epilepsy, are known to have particularly high rates of mental ...
Bennett, S, Coughtrey, A, DeJong, M, Heyman, I, Shafran, R, Simmonds, J, Stephenson, T, Varadkar, S   +7 more
core   +2 more sources

Managing Paraneoplastic Neurological Disorders

The Oncologist, 2006
Learning Objectives After completing this course, the reader will be able to: Describe the autoimmune pathogenesis of paraneoplastic neurological syndromes.Explain the clinical value of paraneoplastic antibody detection.Describe the general treatment approach to paraneoplastic neurological syndromes.
Beukelaar, Janet, Sillevis Smitt, Peter
openaire   +3 more sources

Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis

Nature Communications, 2018
During development, dendrites display structural plasticity, as reflected in the appearance of long, thin and highly motile dendritic filopodia. Here, the authors examine dendritic dynamics of ventral lateral neurons in the developing Drosophila larva ...
Chengyu Sheng, Uzma Javed, Mary Gibbs, Caixia Long, Jun Yin, Bo Qin, Quan Yuan   +6 more
doaj   +1 more source

Shared and unique effects of ApoEε4 and pathogenic gene mutation on cognition and imaging in preclinical familial Alzheimer’s disease

Alzheimer’s Research & Therapy, 2023
Background Neuropsychology and imaging changes have been reported in the preclinical stage of familial Alzheimer’s disease (FAD). This study investigated the effects of APOEε4 and known pathogenic gene mutation on different cognitive domains and circuit ...
Meina Quan, Qi Wang, Wei Qin, Wei Wang, Fangyu Li, Tan Zhao, Tingting Li, Qiongqiong Qiu, Shuman Cao, Shiyuan Wang, Yan Wang, Hongmei Jin, Aihong Zhou, Jiliang Fang, Longfei Jia, Jianping Jia   +15 more
doaj   +1 more source

Duloxetine and venlafaxine induced akathisia: two case reports

Psychiatry and Clinical Psychopharmacology, 2021
Akathisia is a movement disorder characterized by involuntary movements resulting in discomfort and restlessness. Drug-induced akathisia is often seen with antidopaminergic antipsychotics but sometimes can be seen with other drugs.
Filiz Izci, Selma Bozkurt Zincir, Guler Acar, Umit Basar Semiz   +3 more
doaj   +1 more source

International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs [PDF]

, 2015
This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research ...
A Pákozdy, Akos Pakozdy, Andrea Fischer, Andrea Tipold, AT Berg, BG Licht, C Brauer, C Brauer, CL Mariani, Clare Rusbridge, EE Patterson, EE Patterson, G Urkasemsin, Heidrun Potschka, Holger A. Volk, J Guevar, Jacques Penderis, JJ Lin, JL Gill, JW Schmidley, Karen Muñana, Kaspar Matiasek, KJ Ekenstedt, L Arrol, LM Mellema, Luisa De Risio, M Armaşu, M Berendt, M Podell, M Schwartz, M Schwartz, M Wolf, Martí Pumarola Batlle, Mette Berendt, Michael Podell, N Shihab, Ned Patterson, O Devinsky, Paul JJ. Mandigers, PM Smith, R Edwards, R Erro, R Gonçalves, R Poma, R Zimmermann, RMA Packer, Robyn Farqhuar, Rowena MA Packer, RS Fisher, RS Fisher, S Shorvon, Sam Long, Simon Platt, Sofie Bhatti, TM Ghormle, V Hülsmeyer, Veronika Stein, WB Thomas, WW Bush, YC Huang   +59 more
core   +8 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]

, 1999
Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core