Results 71 to 80 of about 1,108,914 (332)

Novel homozygous GBA2 mutation in a patient with complicated spastic paraplegia [PDF]

, 2018
Hereditary spastic paraplegias (HSPs) are a heterogeneous group of neurological disorders characterized primarily by a pyramidal syndrome with lower limb spasticity, which can manifest as pure HSP or associated with a number of neurological or non ...
Bertini, Enrico, Coarelli, Giulia, Ferraldeschi, Michela, Fornasiero, Arianna, Frontali, Marina, Nicita, Francesco, Ristori, Giovanni, Romano, Silvia, Salvetti, Marco, Spadaro, Maria, Travaglini, Lorena   +10 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Modulation of functionally localized right insular cortex activity using real-time fMRI-based neurofeedback

Frontiers in Human Neuroscience, 2013
The capacity for subjects to learn to volitionally control localized brain activity using neurofeedback is actively being investigated. We aimed to investigate the ability of healthy volunteers to quickly learn to use visual feedback during real-time ...
Brian D Berman, Brian D Berman, Silvina G Horovitz, Mark eHallett   +3 more
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Causal relationships between type 1 diabetes mellitus and Alzheimer’s disease and Parkinson’s disease: a bidirectional two-sample Mendelian randomization study

European Journal of Medical Research
Background Previous compelling evidence suggests an association between Type 2 diabetes (T2D) and neurodegenerative diseases. However, it remains uncertain whether Type 1 diabetes mellitus (T1DM) exerts a causal influence on the risk of Alzheimer's ...
Chaofan Geng, Ke Meng, Bo Zhao, Xiaoduo Liu, Yi Tang   +4 more
doaj   +1 more source

Non-speech oro-motor exercise use in acquired dysarthria management : regimes and rationales [PDF]

, 2011
Non-speech oro-motor exercises (NSOMExs) are described in speech and language therapy (SLT) manuals, and are thought to be much used in acquired dysarthria intervention, though there is no robust evidence of an influence on speech outcome.
Allen, Carolyn, Mackenzie, Catherine, Muir, Margaret   +2 more
core   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

A multifactorial study on nutritional status, binge eating and physical activity as main factors directly influencing body weight in Parkinson’s disease

npj Parkinson's Disease, 2017
Weight lossisa multifactorial disorder commonly affecting Parkinson’s disease patients. The aim of this study was to investigate the relationship between body weight, nutritional status, physical activity, and Parkinson’s disease-related factors. A total
Andrea Bril, Santiago Perez-Lloret, Malco Rossi, Sofía Fariña, Pierre Morisset, Laura Sorrentino, Micaela Iglesias, Alex Medina Escobar, Patricio Millar Vernetti, Daniel Cerquetti, Marcelo Merello   +10 more
doaj   +1 more source

Communication difficulties following right hemisphere stroke : applying evidence to clinical management [PDF]

, 2008
Following reports in the 1960s that language may be affected by right hemisphere (RH) lesions, many limitations to effective communication in the right hemisphere damaged (RHD) population have been described and evidenced.
Brady, Marain, Mackenzie, Catherine
core   +1 more source

Paraneoplastic Neurological Disorders

Journal of the Royal College of Physicians of London, 1999
Distinct syndromes are associated with a limited range of tumours. Autoantibodies are provoked by tumour (onconeural) antigens. Paraneoplastic antibodies to ion channels (VGCC, VGKC, AChR) are disease-inducing, but may also slow tumour growth in the case of LEMS.
openaire   +2 more sources