Dilatation of Virchow-Robin spaces in children hospitalized at pediatric neurology department [PDF]
, 2014 Background and purpose: Dilated Virchow-Robin spaces (dVRs) have been revealed by magnetic resonance imaging (MRI) in patients with various neurological disorders. However, their etiology and clinical importance have not been discovered yet.
Biedroń, Agnieszka +3 more
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Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases [PDF]
Journal of Neuroinflammation, 2012 The central nervous system (CNS) is now known to actively communicate with the immune system to control immune responses both centrally and peripherally. Within the CNS, while studies on glial cells, especially microglia, have highlighted the importance of this cell type in innate immune responses of the CNS, the immune regulatory functions of other ...
Tian, Li +3 more
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MicroRNA-Mediated Silencing Pathways in the Nervous System and Neurological Diseases
Cells, 2022 MicroRNAs (miRNAs) are small noncoding RNAs that play a prominent role in post-transcriptional gene regulation mechanisms in the brain tuning synaptic plasticity, memory formation, and cognitive functions in physiological and pathological conditions [...]
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Clinical Relevance of Cerebrospinal Fluid in Dogs (Review) [PDF]
, 2019 From the early 20th century, the cerebrospinal fluid (CSF) analysis was an invaluable diagnostic process in clinical neurology and later in veterinary neurology.
DANCIU, Cecilia Gabriella +3 more
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As contribuições neurológicas de William Osler [PDF]
, 2013 William Osler was one of the most remarkable clinicians worldwide, and his teachings in medical practice remain until the present days. Although Osler had never considered himself a neurologist, he contributed with clinical and pathological descriptions ...
Barsottini, Orlando Graziani Povoas +1 more
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Management of disease-modifying treatments in neurological autoimmune diseases of the central nervous system [PDF]
Clinical and Experimental Immunology, 2014 Summary The therapeutic armamentarium for autoimmune diseases of the central nervous system, specifically multiple sclerosis and neuromyelitis optica, is steadily increasing, with a large spectrum of immunomodulatory and immunosuppressive agents targeting different mechanisms of the immune system.
Andrew T. Chan, R. Gold, A. Salmen
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Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system [PDF]
Expert Review of Neurotherapeutics, 2020 Introduction: Metformin is currently first line therapy for type 2 diabetes (T2D). The mechanism of action of metformin involves activation of AMP-activated protein kinase (AMPK) to enhance mitochondrial function (for example, biogenesis, refurbishment and dynamics) and autophagy.
Demaré, Sarah +3 more
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The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases [PDF]
, 2013 BACKGROUND: Following the characterization of the chemical structure of D9-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, researchers have moved on with scientific valuable explorations.
Di Giannantonio, M. +7 more
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MicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological Diseases [PDF]
International Journal of Molecular Sciences, 2016 MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate gene expression post-transcriptionally. They have been demonstrated to regulate a lot of biological pathways and cellular functions. Many miRNAs are dynamically regulated during central nervous system (CNS) development and are spatially expressed in adult brain ...
Lu Li, Wai-Yee Chan, Dandan Cao
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Covid-19: Involvement of the nervous system. Identifying neurological predictors defining the course of the disease [PDF]
Journal of the Neurological Sciences, 2021 The main objective of this study was to analyse neurological symptoms during a Covid-19 infection and determine the pattern of symptoms by comparing outpatients with inpatients. A further goal was to identify possible predictors, such as pre-existing conditions and neurological symptoms. We recorded the clinical data of 40 inpatients and 42 outpatients
Udo A. Zifko +7 more
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