Results 31 to 40 of about 527,553 (336)

Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome.

open access: yesJAMA Neurology, 2021
Importance Coronavirus disease 2019 (COVID-19) affects the nervous system in adult patients. The spectrum of neurologic involvement in children and adolescents is unclear.
Kerri L LaRovere   +47 more
semanticscholar   +1 more source

miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS [PDF]

open access: yes, 2019
ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
et al,, Mar, Soe
core   +6 more sources

Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient

open access: yesFluids and Barriers of the CNS, 2020
Background The cerebrospinal fluid (CSF)/serum quotient of albumin (QAlb) is the most used biomarker for the evaluation of blood–cerebrospinal fluid barrier (B-CSF-B) permeability.
Massimiliano Castellazzi   +12 more
doaj   +1 more source

As contribuições neurológicas de William Osler [PDF]

open access: yes, 2013
William Osler was one of the most remarkable clinicians worldwide, and his teachings in medical practice remain until the present days. Although Osler had never considered himself a neurologist, he contributed with clinical and pathological descriptions ...
Barsottini, Orlando Graziani Povoas   +1 more
core   +3 more sources

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis [PDF]

open access: yesJournal of Neuroinflammation, 2019
Development of central nervous system (CNS) is regulated by both intrinsic and peripheral signals. Previous studies have suggested that environmental factors affect neurological activities under both physiological and pathological conditions. Although there is anatomical separation, emerging evidence has indicated the existence of bidirectional ...
Qianquan Ma   +5 more
openaire   +3 more sources

Cell-surface central nervous system autoantibodies: Clinical relevance and emerging paradigms

open access: yesAnnals of Neurology, 2014
The recent discovery of several potentially pathogenic autoantibodies has helped identify patients with clinically distinctive central nervous system diseases that appear to benefit from immunotherapy.
S. Irani   +3 more
semanticscholar   +1 more source

Brain Ischemia Significantly Alters microRNA Expression in Human Peripheral Blood Natural Killer Cells

open access: yesFrontiers in Immunology, 2020
Brain ischemia induces systemic immunosuppression and increases a host's susceptibility to infection. MicroRNAs (miRNAs) are molecular switches in immune cells, but the alterations of miRNAs in human immune cells in response to brain ischemia and their ...
Ying Kong   +13 more
doaj   +1 more source

Genome-Wide Multiple Sclerosis Association Data and Coagulation [PDF]

open access: yes, 2019
The emerging concept of a crosstalk between hemostasis, inflammation, and immune system prompt recent works on coagulation cascade in multiple sclerosis (MS).
Arianna Fornasiero   +10 more
core   +2 more sources

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

open access: yesLancet Neurology
Summary Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19.
Jaimie D Steinmetz   +499 more
semanticscholar   +1 more source

Viral vectors in neurodegenerative diseases: immune responses and therapeutic applications

open access: yesFrontiers in Neurology
Gene transfer-based therapies utilizing viral vectors have undergone remarkable advancements and hold significant promise in addressing neurodegenerative diseases in recent years, whose potential mechanisms include replacing or silencing pathogenic genes
Yifei Wang   +8 more
doaj   +1 more source

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