Results 91 to 100 of about 115,230 (317)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Chronic adaptive deep brain stimulation for Parkinson’s disease: clinical outcomes and programming strategies

npj Parkinson's Disease
Adaptive deep brain stimulation (DBS) dynamically adjusts stimulation amplitude based on neurophysiological feedback and may alleviate residual motor fluctuations in patients with Parkinson’s disease.
Johannes L. Busch, Jonathan Kaplan, Jennifer K. Behnke, Victoria S. Witzig, Luisa Drescher, Jeroen G. V. Habets, Andrea A. Kühn   +6 more
doaj   +1 more source

Prospects of neuromodulation for chronic pain

Brain Disorders, 2022
Background: For over half a century neuromodulation has been successfully used for treatment of chronic pain syndromes. There is a growing number of new modes or targets of neurostimulation, a widening of indications and continuous improvement in ...
Emil D. Isagulyan, Valentina A. Mikhailova, Karina S. Aslakhanova, Konstantin V. Slavin   +3 more
doaj   +1 more source

3D‐Printable, Honeycomb‐Inspired Tissue‐Like Bioelectrodes for Patient‐Specific Neural Interface

Advanced Materials, EarlyView.
3D printed MRI‐compatible tissue‐like neural electrodes tailored to individual gyral patterns. This honeycomb‐inspired printable gel electrode (HiPGE) employs a bioinspired architecture with soft hydrogels, engineered to match the softness of brain tissue.
Marzia Momin, Luyi Feng, Xiaoai Chen, Salahuddin Ahmed, Basma AlMahmood, Li‐Pang Huang, Jiashu Ren, Xinyi Wang, Hyunjin Lee, Samuel R. Cramer, Nanyin Zhang, Sulin Zhang, Tao Zhou   +12 more
wiley   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Electrochemical and biological performance of hierarchical platinum-iridium electrodes structured by a femtosecond laser

Microsystems & Nanoengineering, 2022
Neural electrode interfaces are essential to the stimulation safety and recording quality of various bioelectronic therapies. The recently proposed hierarchical platinum-iridium (Pt-Ir) electrodes produced by femtosecond lasers have exhibited superior ...
Linze Li, Changqing Jiang, Wanru Duan, Zhiyan Wang, Feng Zhang, Changgeng He, Tiangang Long, Luming Li   +7 more
doaj   +1 more source

Localized Temperature Monitoring in Mouse Brain during Light Delivery via a Non‐Planar Tapered Fiber‐Integrated µRTD Sensor

Advanced Materials, EarlyView.
We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena, Marco Bianco, Barbara Spagnolo, Muhammad Fayyaz Kashif, Alberto Bramati, Massimo De Vittorio, Ferruccio Pisanello   +6 more
wiley   +1 more source

Exploratory evaluation of spinal cord stimulation with dynamic pulse patterns: a promising approach to improve stimulation sensation, coverage of pain areas, and expected pain relief

Frontiers in Pain Research
BackgroundThe societal burden of chronic pain and the contribution-in-part to the opioid crisis, is a strong motivation to improve and expand non-addictive treatments, including spinal cord stimulation (SCS).
Changfang Zhu, Rosana Esteller, Jessica Block, Kristen Lechleiter, Robert Frey, Michael A. Moffitt   +5 more
doaj   +1 more source

Novel compound heterozygous variants in the PCCB gene causing adult-onset propionic acidemia presenting with neuropsychiatric symptoms: a case report and literature review

BMC Medical Genomics, 2022
Background Propionic acidemia (PA) is a rare autosomal recessive disorder of metabolism caused by mutations in the PCCA or PCCB gene, leading to propionyl CoA carboxylase (PCC) enzyme deficiencies.
Yingxuan Li, Miaomiao Wang, Zhaoyang Huang, Jing Ye, Yuping Wang   +4 more
doaj   +1 more source

Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs [PDF]

, 2019
Background High output subcutaneous nerve stimulation (ScNS) remodels the stellate ganglia and suppresses cardiac arrhythmia. Objective To test the hypothesis that long duration low output ScNS causes cardiac nerve sprouting, increases plasma ...
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Fishbein, Michael C., Grant, Maria B., Shen, Changyu, Wan, Juyi, Wang, Zhuo, Wong, Johnson, Yuan, Yuan   +10 more
core   +1 more source