Results 91 to 100 of about 83,847 (352)

Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action. [PDF]

, 2019
Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers an implantable, non-pharmacologic treatment for patients with intractable chronic pain conditions. Chronic pain is a widely heterogenous syndrome with regard to
Baker, Dewleen G, Caylor, Jacob, Cui, Christina, Huang, Charles, Huang, Mingxiong, Lerman, Imanuel, Narouze, Samer, Ramesh, Rao, Reddy, Rajiv, Simmons, Alan, Souza, Dmitri, Vallejo, Ricardo, Yin, Sopyda   +12 more
core  

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

Advanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini, Mariarosaria De Simone, Martina Blasio, Claudia Zenna, Angela Tino, Eleni Stavrinidou, Silvia Santillo, Claudia Tortiglione   +7 more
wiley   +1 more source

Electronic schematic for bio-plausible dopamine neuromodulation of eSTDP and iSTDP [PDF]

arXiv, 2018
In this technical report we present novel results of the dopamine bio-plausible neuromodulation excitatory (eSTDP) and inhibitory (iSTDP) learning. We present the principal schematic for the neuromodulation of D1 and D2 receptors of dopamine, wiring schematic for both cases as well as the simulatory experiments results done in LTSpice.
arxiv  

Presynaptic modulation as fast synaptic switching: state-dependent modulation of task performance

, 2003
Neuromodulatory receptors in presynaptic position have the ability to suppress synaptic transmission for seconds to minutes when fully engaged. This effectively alters the synaptic strength of a connection.
Scheler, Gabriele, Schumann, Johann
core   +1 more source

Cluster headache management and beyond [PDF]

, 2015
The therapeutic management of cluster headache is based on a very stable triad of drugs. Acute treatment has, in subcutaneous sumatriptan, its gold standard if compared to pure oxygen or indomethacin.
Martelletti, Paolo
core   +1 more source

Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design

Advanced Materials Technologies, EarlyView.
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo, Bhavna Gupta, Akash Saxena, Alexandra P. Veltri, Wen Li, James R. Siegenthaler, Erin K. Purcell   +6 more
wiley   +1 more source

Oxytocin’s social and stress-regulatory effects in children with autism and intellectual disability: a protocol for a randomized placebo-controlled trial

BMC Psychiatry
Background Oxytocin is increasingly considered as a new pharmacological option for mitigating social difficulties and regulating stress in autism spectrum disorder. However, in prior trials, autistic individuals with co-occurring intellectual disability (
G. Ricchiuti, A. Taillieu, E. Tuerlinckx, J. Prinsen, E. Debbaut, J. Steyaert, B. Boets, Kaat Alaerts   +7 more
doaj   +1 more source

Neuromodulated Learning in Deep Neural Networks [PDF]

arXiv, 2018
In the brain, learning signals change over time and synaptic location, and are applied based on the learning history at the synapse, in the complex process of neuromodulation. Learning in artificial neural networks, on the other hand, is shaped by hyper-parameters set before learning starts, which remain static throughout learning, and which are ...
arxiv  

Evolutionary Divergence in Developmental Strategies and Neuromodulatory Control Systems of Two Amphibian Locomotor Networks [PDF]

, 2004
Attempts to understand the neural mechanisms which produce behaviour must consider both prevailing sensory cues and the central cellular and synaptic changes they direct. At each level, neuromodulation can additionally shape the final output.
Buchanan, James T., McLean, David L., Merrywest, Simon D., Sillar, Keith T.   +3 more
core   +2 more sources

Chemical AI in the Limelight: The Contribution of Photochromic Materials and Oscillatory Chemical Reactions

Advanced Optical Materials, EarlyView.
Photochromic compounds are versatile ingredients for the development of Chemical AI. When they are embedded in a tight microenvironment, they become Markov blankets. They are also valuable for processing Boolean and Fuzzy logic. They contribute to neuromorphic engineering in wetware based on opto‐chemical signals exchanged with oscillatory chemical ...
Pier Luigi Gentili
wiley   +1 more source