Results 101 to 110 of about 89,973 (328)

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source

A Cost Effectiveness Analysis of Spinal Cord Stimulation versus Conventional Medical Management for the Treatment of Low Back Pain Using Data from DISTINCT RCT and Medical Claims from a U.S. Commercial Payer Database

Journal of Pain Research
Timothy Deer,1,* Robert Heros,2,* Keith Scarfo,3 Christopher Gilligan,4 Jessica Jameson,5 Julie G Pilitsis,6 Mehul J Desai,7 Thadchaigeni Panchalingam,8 Scott Goates,8 Alexander M Benison,8 Udoka Okaro,8 Steven Falowski9 1The Spine and ...
Deer T, Heros R, Scarfo K, Gilligan C, Jameson J, Pilitsis JG, Desai MJ, Panchalingam T, Goates S, Benison AM, Okaro U, Falowski S   +11 more
doaj  

Microfabrication Technologies for Nanoinvasive and High‐Resolution Magnetic Neuromodulation

Advanced Science
The increasing demand for precise neuromodulation necessitates advancements in techniques to achieve higher spatial resolution. Magnetic stimulation, offering low signal attenuation and minimal tissue damage, plays a significant role in neuromodulation ...
Changhao Ge, Tahereh Masalehdan, Mahdieh Shojaei Baghini, Vicente Duran Toro, Lorenzo Signorelli, Hannah Thomson, Danijela Gregurec, Hadi Heidari   +7 more
doaj   +1 more source

Neuroprosthetic-enabled control of graded arm muscle contraction in a paralyzed human

Scientific Reports, 2017
Neuroprosthetics that combine a brain computer interface (BCI) with functional electrical stimulation (FES) can restore voluntary control of a patients’ own paralyzed limbs.
David A. Friedenberg, Michael A. Schwemmer, Andrew J. Landgraf, Nicholas V. Annetta, Marcia A. Bockbrader, Chad E. Bouton, Mingming Zhang, Ali R. Rezai, W. Jerry Mysiw, Herbert S. Bresler, Gaurav Sharma   +10 more
doaj   +1 more source

Enhanced Brain‐Heart Connectivity as a Precursor of Reduced State Anxiety after Therapeutic Virtual Reality Immersion

Advanced Science, EarlyView.
This study shows that enhanced brain‐to‐heart coupling is a precursor of anxiety reduction following a virtual reality‐based non‐pharmacological intervention. Driven by midline beta rhythms, this effect suggests the involvement of central‐autonomic interactions.
Idil Sezer, Paul Moreau, Mohamad El Sayed Hussein Jomaa, Valérie Godefroy, Bénédicte Batrancourt, Richard Lévy, Anton Filipchuk   +6 more
wiley   +1 more source

Multifunctionality in embodied agents: Three levels of neural reuse [PDF]

, 2018
The brain in conjunction with the body is able to adapt to new environments and perform multiple behaviors through reuse of neural resources and transfer of existing behavioral traits.
Candadai, Madhavun, Izquierdo, Eduardo
core   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

Advanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He, Yifan Du, Ziqi Fu, Youcun Zheng, Nils Muhlert, Barbara Sahakian, Rebecca Elliott   +6 more
wiley   +1 more source

Neuropeptides in the Extracellular Space of the Mouse Cortex Measured In Vivo by Nanodialysis Probe Coupled with LC‐MS

Angewandte Chemie, EarlyView.
This study reveals a complex peptidomic landscape in the mouse somatosensory cortex, identifying locally released and potentially transported neuropeptides using a membrane‐free nanodialysis sampling probe coupled with nanoLC‐timsTOF mass spectrometry.
Keyin Li, Weihua Shi, Yanqi Tan, Yu Ding, Alex G. Armstrong, Yurii Vlasov, Jonathan V. Sweedler   +6 more
wiley   +2 more sources

Brain-machine interactive neuromodulation research tool with edge AI computing

Heliyon
Closed-loop neuromodulation with intelligence methods has shown great potentials in providing novel neuro-technology for treating neurological and psychiatric diseases.
Yan Li, Yingnan Nie, Zhaoyu Quan, Han Zhang, Rui Song, Hao Feng, Xi Cheng, Wei Liu, Xinyi Geng, Xinwei Sun, Yanwei Fu, Shouyan Wang   +11 more
doaj   +1 more source

Triple leads with longitudinal guarded cathodes in spinal cord stimulation-effect of transversal lead separation [PDF]

, 2009
In spinal cord stimulation (SCS) clinical practice, longitudinal guarded cathode stimulation by a single lead, placed on the spinal cord midline provides the broadest parasthesia coverage.
Buitenweg, J.R., Holsheimer, J., Sankarasubramanian, V   +2 more
core   +1 more source