Results 41 to 50 of about 71,159 (193)

cpCST: a new continuous performance test for high-precision assessment of attention across the lifespan

Frontiers in Psychology
IntroductionAssessing sustained attention presents methodological challenges, particularly when spanning diverse populations whose baseline sensorimotor functioning may vary significantly.MethodsThis study introduces the Continuous Performance Critical ...
Anna MacKay-Brandt, Daniel Garcia-Barnett, Kai Xuan Gan, Olivia Ripley, Elaine Gazes, Michael Milham, Michael Milham, Stan Colcombe, Stan Colcombe, Stan Colcombe, Stan Colcombe   +10 more
doaj   +1 more source

Chronic adaptive deep brain stimulation for Parkinson’s disease: clinical outcomes and programming strategies

npj Parkinson's Disease
Adaptive deep brain stimulation (DBS) dynamically adjusts stimulation amplitude based on neurophysiological feedback and may alleviate residual motor fluctuations in patients with Parkinson’s disease.
Johannes L. Busch, Jonathan Kaplan, Jennifer K. Behnke, Victoria S. Witzig, Luisa Drescher, Jeroen G. V. Habets, Andrea A. Kühn   +6 more
doaj   +1 more source

Exploratory evaluation of spinal cord stimulation with dynamic pulse patterns: a promising approach to improve stimulation sensation, coverage of pain areas, and expected pain relief

Frontiers in Pain Research
BackgroundThe societal burden of chronic pain and the contribution-in-part to the opioid crisis, is a strong motivation to improve and expand non-addictive treatments, including spinal cord stimulation (SCS).
Changfang Zhu, Rosana Esteller, Jessica Block, Kristen Lechleiter, Robert Frey, Michael A. Moffitt   +5 more
doaj   +1 more source

Closed-loop deep brain stimulation by pulsatile delayed feedback with increased gap between pulse phases

Scientific Reports, 2017
Computationally it was shown that desynchronizing delayed feedback stimulation methods are effective closed-loop techniques for the control of synchronization in ensembles of interacting oscillators. We here computationally design stimulation signals for
Oleksandr V. Popovych, Borys Lysyansky, Peter A. Tass   +2 more
doaj   +1 more source

Electrochemical and biological performance of hierarchical platinum-iridium electrodes structured by a femtosecond laser

Microsystems & Nanoengineering, 2022
Neural electrode interfaces are essential to the stimulation safety and recording quality of various bioelectronic therapies. The recently proposed hierarchical platinum-iridium (Pt-Ir) electrodes produced by femtosecond lasers have exhibited superior ...
Linze Li, Changqing Jiang, Wanru Duan, Zhiyan Wang, Feng Zhang, Changgeng He, Tiangang Long, Luming Li   +7 more
doaj   +1 more source

Identifying neurobiological heterogeneity in clinical high-risk psychosis: a data-driven biotyping approach using resting-state functional connectivity

Schizophrenia
To explore the neurobiological heterogeneity within the Clinical High-Risk (CHR) for psychosis population, this study aimed to identify and characterize distinct neurobiological biotypes within CHR using features from resting-state functional networks. A
Xiaochen Tang, Yanyan Wei, Jiaoyan Pang, Lihua Xu, Huiru Cui, Xu Liu, Yegang Hu, Mingliang Ju, Yingying Tang, Bin Long, Wei Liu, Min Su, Tianhong Zhang, Jijun Wang   +13 more
doaj   +1 more source

Novel compound heterozygous variants in the PCCB gene causing adult-onset propionic acidemia presenting with neuropsychiatric symptoms: a case report and literature review

BMC Medical Genomics, 2022
Background Propionic acidemia (PA) is a rare autosomal recessive disorder of metabolism caused by mutations in the PCCA or PCCB gene, leading to propionyl CoA carboxylase (PCC) enzyme deficiencies.
Yingxuan Li, Miaomiao Wang, Zhaoyang Huang, Jing Ye, Yuping Wang   +4 more
doaj   +1 more source

Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]

, 2008
Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C.
core   +3 more sources

Oxytocin’s social and stress-regulatory effects in children with autism and intellectual disability: a protocol for a randomized placebo-controlled trial

BMC Psychiatry
Background Oxytocin is increasingly considered as a new pharmacological option for mitigating social difficulties and regulating stress in autism spectrum disorder. However, in prior trials, autistic individuals with co-occurring intellectual disability (
G. Ricchiuti, A. Taillieu, E. Tuerlinckx, J. Prinsen, E. Debbaut, J. Steyaert, B. Boets, Kaat Alaerts   +7 more
doaj   +1 more source

Neuromodulation

, 2017
This chapter addresses the indications for and complications related to surgical, pharmacologic, and adjunctive neuromodulation therapy. Many forms of neuromodulation therapy find their inspiration from the landmark work by Melzack and Wall in 1965 that ...
Marc A. Huntoon, Bryan Covert
core   +1 more source